Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Secondary Progressive Multiple Sclerosis (SPMS): full-pipeline trial registry
2 of 2 indexed Secondary Progressive Multiple Sclerosis (SPMS) trials are currently recruiting.
Corpus placement: #7,188 of 28,707 conditions by registered trial count.
2 US clinical trials · 2 currently recruiting · #7,188 of 28,707 conditions by registered trial count
Secondary Progressive Multiple Sclerosis (SPMS): 2 US clinical trials tracked, 2 recruiting.
Secondary Progressive Multiple Sclerosis (SPMS) is the subject of 2 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Tr1X, running 1 of these trials.
Enrollment posture brief
Registry condition secondary-progressive-multiple-sclerosis-spms
OPEN 2 | RECR 100% | LATE 1 | EARLY 1 | RANK #7188 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Aortic Arch Aneurysm (100% recruiting · 5 trials)
Secondary Progressive Multiple Sclerosis (SPMS) lists 2 open slots (100% of 2 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Secondary Progressive Multiple Sclerosis (SPMS) on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Secondary Progressive Multiple Sclerosis (SPMS) is recruiting above its size-band peers.
2 of 2 indexed trials (100%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
Open and recent trials
2 total, page 1 of 1
A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis
Novartis Pharmaceuticals
NCT07225504
Treatment of Participants With Primary or Secondary Progressive Multiple Sclerosis
Tr1X
NCT07477639
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 3 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Secondary Progressive Multiple Sclerosis (SPMS) records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Secondary Progressive Multiple Sclerosis (SPMS) trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Secondary Progressive Multiple Sclerosis (SPMS) page
2 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 2 Secondary Progressive Multiple Sclerosis (SPMS) trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Tr1X sponsors the most Secondary Progressive Multiple Sclerosis (SPMS) trials on record, review their full trial history before evaluating a specific study. See Tr1X's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Secondary Progressive Multiple Sclerosis (SPMS) condition card totals 2 registered trials; most-linked intervention TRX319; top US site state Kansas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.