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ClinicalTrials.gov 3 recruiting now early-phase tilt

Rosacea: early-phase trial registry

3 of 24 indexed Rosacea trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #686 of 28,707 conditions by registered trial count.

24 US clinical trials · 3 currently recruiting · #686 of 28,707 conditions by registered trial count

Rosacea: 24 US clinical trials tracked, 3 recruiting.

Rosacea is the subject of 24 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 7 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is Galderma R&D, running 5 of these trials.

Enrollment posture brief

Registry condition rosacea

OPEN 3 | RECR 13% | LATE 7 | EARLY 12 | RANK #686 | SPON 5

Nearest open-share peer: Acute Respiratory Infection (13% recruiting · 8 trials)

Aplastic Anemia37.5%Behavior37.5%Rosacea (this)13%Allergic Rhinitis8.3%Adult Acute Myeloid Leukemia0%
Open-enrollment share among volume-matched conditions near Rosacea

Rosacea lists 3 open slots (13% of 24 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Rosacea on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Rosacea is recruiting below its size-band peers.

    3 of 24 indexed trials (12.5%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Rosacea research.

    Galderma R&D accounts for 5 of 24 trials (20.8%). 17 distinct sponsors appear on at least one study for this condition label.

  3. Typical Rosacea enrolment sits around 117 participants.

    Median target enrolment is 117 among the 24 trials that report a genuine target (sentinel values excluded). 12 of those (50%) plan for fewer than 100 participants.

  4. Rosacea research is mostly interventional.

    23 interventional and 1 observational studies make up this index (95.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 17Phase 25Phase 35Phase 42

Open and recent trials

24 total, page 1 of 1

RECRUITING NA 150 participants

The Use of Image-Based Computer Gradings in the Analysis of Acne, Rosacea, Melasma, and Seborrheic Dermatitis

Integrative Skin Science and Research

NCT05942248

RECRUITING Phase 2 48 participants

Evaluating Use of Topical Imipramine and Amitriptyline in Reducing Ultraviolet B Light-Induced Redness in Patients With Rosacea

Wright State University

NCT06312813

RECRUITING NA 24 participants

Effects of Oral Supplement Containing L-Histidine and Antioxidants on the Skin Barrier Function and Systemic Inflammation in Rosacea

Integrative Skin Science and Research

NCT06072066

ACTIVE NOT RECRUITING Early Phase 1 150 participants

Analysis of the Microbiome in Rosacea

Johns Hopkins University

NCT04108897

COMPLETED Phase 4 1,421 participants

ORCA - Oracea® for Rosacea: A Community-based Assessment

Galderma R&D

NCT00892281

COMPLETED Phase 3 667 participants

Bioequivalence Study of Two Treatments in the Treatment of Inflammatory Lesions of Rosacea on the Face

Padagis

NCT02800148

COMPLETED Phase 1 602 participants

A Therapeutic Equivalence Study of Two Metronidazole 1%Topical Gel Treatments for Patients With Rosacea

Sun Pharmaceutical Industries

NCT01513863

COMPLETED Phase 3 449 participants

Study of CD07805/47 Topical Gel in Subjects With Facial Erythema Associated With Rosacea

Galderma R&D

NCT01318733

COMPLETED Phase 2 357 participants

AGN-199201 for the Treatment of Erythema With Rosacea

Allergan

NCT01735201

COMPLETED Phase 3 307 participants

Study to Evaluate the Long-term Safety of a Once-Daily Omiganan Topical Gel

Maruho Co.

NCT02576847

COMPLETED 306 participants

Genetic Basis of Rosacea

Stanford University

NCT02787616

COMPLETED Phase 2 269 participants

Efficacy and Safety Study of CD07805/47 Topical Gel in Subjects With Facial Erythema Associated With Rosacea

Galderma R&D

NCT01174030

COMPLETED Phase 3 260 participants

Phase 3 Efficacy and Safety Study of CD07805/47 Topical Gel in Subjects With Facial Erythema Associated With Rosacea

Galderma R&D

NCT01355458

COMPLETED NA 117 participants

A Study to Evaluate the Safety, Tolerability, and Effects of Anatabloc® Crème in Rosacea

Rock Creek Pharmaceuticals

NCT01740934

COMPLETED Phase 2 92 participants

A Study of DER 45-EV Gel to Treat Rosacea

Sol-Gel Technologies

NCT00940992

COMPLETED Phase 3 70 participants

Efficacy and Safety Study Comparing CD07805/47 Gel 0.5% to Azelaic Acid Gel 15% in Subjects With Erythema of Rosacea

Galderma R&D

NCT01659853

COMPLETED Phase 1 64 participants

Safety and Tolerability of AGN-199201 in Patients With Erythema Associated With Rosacea

Allergan

NCT01579084

COMPLETED Phase 1 60 participants

Impact of DFD-29 on Microbial Flora of Healthy, Adult Human Subjects When Administered Over 16 Weeks

Journey Medical Corporation

NCT05597462

COMPLETED Phase 4 60 participants

Efficacy of Oral Minocycline (Solodyn) and Oral Minocycline (Solodyn) Plus Azelaic Acid (Finacea) for Acne Rosacea

Dermatology Specialists Research

NCT05014906

COMPLETED NA 35 participants

4 Week In-Use Study Evaluating How Well-Tolerated a Skin Care Product Is on Adults With Facial Redness

Bayer

NCT03841032

COMPLETED Phase 2 30 participants

Rosacea and Ivermectin

Wake Forest University Health Sciences

NCT04275999

COMPLETED Phase 1 25 participants

Evaluation of the Inhibitory Effects of Topical Ivermectin on Markers of Rosacea Specific Inflammation.

University of California, San Diego

NCT02806414

COMPLETED Phase 1 20 participants

Topical Agent for Treatment of Red Skin

Mayo Clinic

NCT00279890

COMPLETED Phase 1 8 participants

Timolol for the Treatment of Acne and Rosacea

Johns Hopkins University

NCT02774590

Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 5
Phase 3 5
Phase 4 2

Named interventions

Most-linked intervention names on Rosacea records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

AGN-199201 Vehicle Drug
2 trials
Vehicle Drug
2 trials
Placebo Drug
2 trials
doxycycline (Oracea®) 40 mg modified release as add-on therapy Drug
1 trials
doxycycline (Oracea®) 40 mg modified release as monotherapy Drug
1 trials
DER 45 EV Drug
1 trials
CD07805/47 gel 0.5% Drug
1 trials
Metronidazole Topical Gel 1% (Metrogel) Drug
1 trials

US sites by state

Facility locations filed on Rosacea trials. A trial with sites in several states counts in each.

Texas 9 trials
California 9 trials
Tennessee 6 trials
North Carolina 6 trials
New York 5 trials
Virginia 4 trials
Pennsylvania 4 trials
Kentucky 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Rosacea page

24 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Rosacea condition card totals 24 registered trials; most-linked intervention AGN-199201 Vehicle; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.