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ClinicalTrials.gov 3 recruiting now official registry

Rosacea clinical trials

Every US clinical trial registered for Rosacea — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

24 US clinical trials · 3 currently recruiting

The research picture

Rosacea has 24 registered US clinical trials, 3 of them open to new participants right now — about 13% of the total.

3
recruiting participants now
13%
of trials open to enrollment
7
in Phase 3–4 (later-stage)
5
top sponsor: Galderma R&D

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING NA 150 participants

The Use of Image-Based Computer Gradings in the Analysis of Acne, Rosacea, Melasma, and Seborrheic Dermatitis

Integrative Skin Science and Research

NCT05942248

RECRUITING Phase 2 48 participants

Evaluating Use of Topical Imipramine and Amitriptyline in Reducing Ultraviolet B Light-Induced Redness in Patients With Rosacea

Wright State University

NCT06312813

RECRUITING NA 24 participants

Effects of Oral Supplement Containing L-Histidine and Antioxidants on the Skin Barrier Function and Systemic Inflammation in Rosacea

Integrative Skin Science and Research

NCT06072066

ACTIVE NOT RECRUITING Early Phase 1 150 participants

Analysis of the Microbiome in Rosacea

Johns Hopkins University

NCT04108897

COMPLETED Phase 4 1,421 participants

ORCA - Oracea® for Rosacea: A Community-based Assessment

Galderma R&D

NCT00892281

COMPLETED Phase 3 667 participants

Bioequivalence Study of Two Treatments in the Treatment of Inflammatory Lesions of Rosacea on the Face

Padagis

NCT02800148

COMPLETED Phase 1 602 participants

A Therapeutic Equivalence Study of Two Metronidazole 1%Topical Gel Treatments for Patients With Rosacea

Sun Pharmaceutical Industries

NCT01513863

COMPLETED Phase 3 449 participants

Study of CD07805/47 Topical Gel in Subjects With Facial Erythema Associated With Rosacea

Galderma R&D

NCT01318733

COMPLETED Phase 2 357 participants

AGN-199201 for the Treatment of Erythema With Rosacea

Allergan

NCT01735201

COMPLETED Phase 3 307 participants

Study to Evaluate the Long-term Safety of a Once-Daily Omiganan Topical Gel

Maruho Co.

NCT02576847

COMPLETED 306 participants

Genetic Basis of Rosacea

Stanford University

NCT02787616

COMPLETED Phase 2 269 participants

Efficacy and Safety Study of CD07805/47 Topical Gel in Subjects With Facial Erythema Associated With Rosacea

Galderma R&D

NCT01174030

COMPLETED Phase 3 260 participants

Phase 3 Efficacy and Safety Study of CD07805/47 Topical Gel in Subjects With Facial Erythema Associated With Rosacea

Galderma R&D

NCT01355458

COMPLETED NA 117 participants

A Study to Evaluate the Safety, Tolerability, and Effects of Anatabloc® Crème in Rosacea

Rock Creek Pharmaceuticals

NCT01740934

COMPLETED Phase 2 92 participants

A Study of DER 45-EV Gel to Treat Rosacea

Sol-Gel Technologies

NCT00940992

COMPLETED Phase 3 70 participants

Efficacy and Safety Study Comparing CD07805/47 Gel 0.5% to Azelaic Acid Gel 15% in Subjects With Erythema of Rosacea

Galderma R&D

NCT01659853

COMPLETED Phase 1 64 participants

Safety and Tolerability of AGN-199201 in Patients With Erythema Associated With Rosacea

Allergan

NCT01579084

COMPLETED Phase 1 60 participants

Impact of DFD-29 on Microbial Flora of Healthy, Adult Human Subjects When Administered Over 16 Weeks

Journey Medical Corporation

NCT05597462

COMPLETED Phase 4 60 participants

Efficacy of Oral Minocycline (Solodyn) and Oral Minocycline (Solodyn) Plus Azelaic Acid (Finacea) for Acne Rosacea

Dermatology Specialists Research

NCT05014906

COMPLETED NA 35 participants

4 Week In-Use Study Evaluating How Well-Tolerated a Skin Care Product Is on Adults With Facial Redness

Bayer

NCT03841032

COMPLETED Phase 2 30 participants

Rosacea and Ivermectin

Wake Forest University Health Sciences

NCT04275999

COMPLETED Phase 1 25 participants

Evaluation of the Inhibitory Effects of Topical Ivermectin on Markers of Rosacea Specific Inflammation.

University of California, San Diego

NCT02806414

COMPLETED Phase 1 20 participants

Topical Agent for Treatment of Red Skin

Mayo Clinic

NCT00279890

COMPLETED Phase 1 8 participants

Timolol for the Treatment of Acne and Rosacea

Johns Hopkins University

NCT02774590

Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 5
Phase 3 5
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Rosacea Trial Landscape

ClinicalTrials.gov lists 24 US studies indexed under Rosacea, and 3 of those are currently open to recruitment — roughly 13% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Rosacea shows 7 late-stage studies (Phase 3 and Phase 4 combined) alongside 12 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Rosacea is led by Galderma R&D with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 24 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Rosacea?

PlainTrial tracks 24 US clinical trials for Rosacea, of which 3 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Rosacea?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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