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NCT04108897 · ClinicalTrials.gov registry record · Early Phase 1
Analysis of the Microbiome in Rosacea
A Early Phase 1 study of Rosacea, sponsored by Johns Hopkins University.
- Active
- Registry status
- Early Phase 1
- Development phase
- 150
- Enrollment target
- 1
- Study location
NCT04108897 is a Early Phase 1 study of Rosacea that is active but no longer recruiting, run by Johns Hopkins University. The registered enrollment target is 150 participants, below the 237-participant average among 23 other Rosacea trials with a reported enrollment target (37% lower). The trial reports 1 study location across 1 state.
The verdict
NCT04108897, a Early Phase 1 study of Rosacea, is active but no longer recruiting, sponsored by Johns Hopkins University.
- ACTIVE NOT RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 150 participants
- Enrollment target
- 1
- Study location
Study Summary
The skin and gut microbiome of rosacea patients differs from individuals without rosacea and that the microbiome suffers from unique derangements in rosacea patients following antibiotic therapy. This study was proposed to examine microbial signatures of the skin and gut microbiome in patients with moderate to severe rosacea and to identify differences between microbe communities in patients with rosacea and volunteers without rosacea using 16S ribosomal ribonucleic acid (rRNA) polymerase chain reaction (PCR) amplification, sequencing and computational phylogenetics and to assess alterations in the gut and skin microbiota of patients with moderate to severe rosacea in response to varying formulations of antimicrobial treatment.
Conditions Studied
Interventions
- DRUG Doxycycline
- DRUG Ivermectin Topical
Study Locations (1)
Maryland
- Cutaneous Translational Research Program, Department of Dermatology - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2019-09-17 |
| Est. Completion | 2027-09 |
| Phase | Early Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04108897
The ClinicalTrials.gov registry entry for NCT04108897 describes a study currently listed as active not recruiting, categorized as Early Phase 1. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 237-participant average among 23 other Rosacea trials with a reported enrollment target (37% lower). The listed sponsor is Johns Hopkins University, which has 1,448 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Rosacea appearing as the primary indexed condition, and to 2 interventions - of which Doxycycline is the first listed.
NCT04108897 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT04108897 about?
NCT04108897 is a clinical study titled "Analysis of the Microbiome in Rosacea". The skin and gut microbiome of rosacea patients differs from individuals without rosacea and that the microbiome suffers from unique derangements in rosacea patients following antibiotic therapy. This study was proposed to examine microbial signatures of the skin and gut microbiome in patients with...
What is the current status of trial NCT04108897?
This trial is currently active not recruiting. It is a Early Phase 1 study. The enrollment target is 150 participants. The study started on 2019-09-17. Estimated completion is 2027-09.
What conditions does trial NCT04108897 study?
This clinical trial studies the following conditions: Rosacea.
What interventions are being tested in trial NCT04108897?
The interventions under investigation include: Doxycycline (DRUG), Ivermectin Topical (DRUG).
Who is sponsoring clinical trial NCT04108897?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04108897 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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