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ClinicalTrials.gov 1 recruiting now early-phase tilt small index

Recurrent Ependymoma: early-phase trial registry

1 of 8 indexed Recurrent Ependymoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #2,176 of 28,707 conditions by registered trial count.

8 US clinical trials · 1 currently recruiting · #2,176 of 28,707 conditions by registered trial count

Recurrent Ependymoma: 8 US clinical trials tracked, 1 recruiting.

Recurrent Ependymoma is the subject of 8 registered US clinical trials on ClinicalTrials.gov, 1 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 6 of these trials.

Enrollment posture brief

Registry condition recurrent-ependymoma

OPEN 1 | RECR 13% | LATE 0 | EARLY 8 | RANK #2176 | SPON 6

Nearest open-share peer: Acute Respiratory Infection (13% recruiting · 8 trials)

Activity, Motor75%Achalasia50%Abdominal Cancer25%Acne Scars - Mixed Atrophic 25%Recurrent Ependymoma (this)13%
Open-enrollment share among volume-matched conditions near Recurrent Ependymoma

Recurrent Ependymoma lists 1 open slots (13% of 8 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Recurrent Ependymoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Recurrent Ependymoma is recruiting below its size-band peers.

    1 of 8 indexed trials (12.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Recurrent Ependymoma research.

    National Cancer Institute (NCI) accounts for 6 of 8 trials (75%). 3 distinct sponsors appear on at least one study for this condition label.

  3. Most Recurrent Ependymoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 13 among the 8 trials that report a genuine target (sentinel values excluded). 6 of those (75%) plan for fewer than 100 participants.

  4. Recurrent Ependymoma research is mostly interventional.

    8 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 27

Open and recent trials

8 total, page 1 of 1

RECRUITING Phase 1 208 participants

ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors

Sabine Mueller, MD, PhD

NCT04732065

ACTIVE NOT RECRUITING Phase 2 1,376 participants

Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

National Cancer Institute (NCI)

NCT03155620

ACTIVE NOT RECRUITING Phase 2 62 participants

131I-Omburtamab, in Recurrent Medulloblastoma and Ependymoma

Pediatric Brain Tumor Consortium

NCT04743661

ACTIVE NOT RECRUITING Phase 2 13 participants

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

National Cancer Institute (NCI)

NCT03213652

ACTIVE NOT RECRUITING Phase 2 9 participants

Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)

National Cancer Institute (NCI)

NCT03213704

ACTIVE NOT RECRUITING Phase 2 5 participants

Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial

National Cancer Institute (NCI)

NCT04284774

ACTIVE NOT RECRUITING Phase 2 3 participants

Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)

National Cancer Institute (NCI)

NCT04195555

ACTIVE NOT RECRUITING Phase 2 1 participants

Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial

National Cancer Institute (NCI)

NCT04320888

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 7

Named interventions

Most-linked intervention names on Recurrent Ependymoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Computed Tomography Procedure
4 trials
Bone Marrow Aspiration and Biopsy Procedure
3 trials
Bone Scan Procedure
3 trials
Biospecimen Collection Procedure
3 trials
Liothyronine Drug
1 trials
Omburtamab I-131 Drug
1 trials
Radionuclide Imaging Procedure
1 trials
Ensartinib Drug
1 trials

US sites by state

Facility locations filed on Recurrent Ependymoma trials. A trial with sites in several states counts in each.

California 8 trials
Arizona 6 trials
Arkansas 6 trials
Alabama 6 trials
Alaska 6 trials
Delaware 2 trials
Connecticut 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Recurrent Ependymoma page

8 registered trials, 1 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Recurrent Ependymoma condition card totals 8 registered trials; most-linked intervention Computed Tomography; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.