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ClinicalTrials.gov 4 recruiting now early-phase tilt small index

Prognostic Stage IV Breast Cancer AJCC v8: early-phase trial registry

4 of 10 indexed Prognostic Stage IV Breast Cancer AJCC v8 trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,724 of 28,707 conditions by registered trial count.

10 US clinical trials · 4 currently recruiting · #1,724 of 28,707 conditions by registered trial count

Prognostic Stage IV Breast Cancer AJCC v8: 10 US clinical trials tracked, 4 recruiting.

Prognostic Stage IV Breast Cancer AJCC v8 is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is Roswell Park Cancer Institute, running 2 of these trials.

Enrollment posture brief

Registry condition prognostic-stage-iv-breast-cancer-ajcc-v8

OPEN 4 | RECR 40% | LATE 0 | EARLY 7 | RANK #1724 | SPON 2

Nearest open-share peer: Acute Myeloid Leukemia (AML) (40% recruiting · 30 trials)

Acute Leukemia of Ambiguous 80%Achondroplasia40%Prognostic Stage IV Brea (th…40%Accelerated Phase Chronic My20%Accidental Fall20%
Open-enrollment share among volume-matched conditions near Prognostic Stage IV Breast Cancer AJCC v8

Prognostic Stage IV Breast Cancer AJCC v8 lists 4 open slots (40% of 10 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Prognostic Stage IV Breast Cancer AJCC v8 on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Prognostic Stage IV Breast Cancer AJCC v8 is recruiting below its size-band peers.

    4 of 10 indexed trials (40%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Prognostic Stage IV Breast Cancer AJCC v8 research.

    Roswell Park Cancer Institute accounts for 2 of 10 trials (20%). 7 distinct sponsors appear on at least one study for this condition label.

  3. Most Prognostic Stage IV Breast Cancer AJCC v8 trials plan to enrol fewer than 100 people.

    Median target enrolment is 44 among the 10 trials that report a genuine target (sentinel values excluded). 6 of those (60%) plan for fewer than 100 participants.

  4. Prognostic Stage IV Breast Cancer AJCC v8 research is mostly interventional.

    9 interventional and 1 observational studies make up this index (90% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 25

Open and recent trials

10 total, page 1 of 1

RECRUITING NA 739 participants

S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

SWOG Cancer Research Network

NCT03723928

RECRUITING 700 participants

Biomarkers and Clinical Features of Metastatic Breast Cancer in Patients Treated With CDK4/6 Inhibitors

Roswell Park Cancer Institute

NCT04526587

RECRUITING Phase 2 43 participants

Abemaciclib and Endocrine Therapy in Older Patients With Breast Cancer.

City of Hope Medical Center

NCT04305834

RECRUITING Phase 2 23 participants

Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab for the Treatment of Brain Metastasis From Triple Negative Breast Cancer or HER2+ Breast Cancer

Roswell Park Cancer Institute

NCT04348747

ACTIVE NOT RECRUITING NA 243 participants

A Video Intervention to Improve Patient Understanding of Tumor Genomic Testing in Patients With Metastatic Cancer

Ohio State University Comprehensive Cancer Center

NCT05215769

ACTIVE NOT RECRUITING Phase 2 138 participants

Using FDG-PET/CT to Assess Response of Bone-Dominant Metastatic Breast Cancer, FEATURE Study

ECOG-ACRIN Cancer Research Group

NCT04316117

ACTIVE NOT RECRUITING Phase 2 44 participants

Testing Sacituzumab Govitecan Therapy in Patients With HER2-Negative Breast Cancer and Brain Metastases

SWOG Cancer Research Network

NCT04647916

ACTIVE NOT RECRUITING Phase 2 25 participants

INCMGA00012 and Pelareorep for the Treatment of Metastatic Triple Negative Breast Cancer, IRENE Study

Mridula George, MD

NCT04445844

ACTIVE NOT RECRUITING Phase 1 14 participants

In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors

University of Southern California

NCT04616248

ACTIVE NOT RECRUITING Phase 1 9 participants

CF33-hNIS-antiPDL1 for the Treatment of Metastatic Triple Negative Breast Cancer

City of Hope Medical Center

NCT05081492

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 5

Named interventions

Most-linked intervention names on Prognostic Stage IV Breast Cancer AJCC v8 records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Questionnaire Administration Other
3 trials
Quality-of-Life Assessment Other
2 trials
Recombinant Flt3 Ligand Biological
1 trials
Oncolytic Virus CF33-expressing hNIS/Anti-PD-L1 Antibody Biological
1 trials
Pelareorep Biological
1 trials
Retifanlimab Biological
1 trials
Anti-CD40 Agonist Monoclonal Antibody CDX-1140 Biological
1 trials
Anti-HER2/HER3 Dendritic Cell Vaccine Biological
1 trials

US sites by state

Facility locations filed on Prognostic Stage IV Breast Cancer AJCC v8 trials. A trial with sites in several states counts in each.

California 6 trials
New York 3 trials
Arizona 3 trials
Ohio 2 trials
Florida 2 trials
Arkansas 2 trials
Alaska 2 trials
Virginia 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Prognostic Stage IV Breast Cancer AJCC v8 page

10 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 4 Prognostic Stage IV Breast Cancer AJCC v8 trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Roswell Park Cancer Institute sponsors the most Prognostic Stage IV Breast Cancer AJCC v8 trials on record, review their full trial history before evaluating a specific study. See Roswell Park Cancer Institute's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Prognostic Stage IV Breast Cancer AJCC v8 condition card totals 10 registered trials; most-linked intervention Questionnaire Administration; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.