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NCT04305834 · ClinicalTrials.gov registry record · Phase 2

Abemaciclib and Endocrine Therapy in Older Patients With Breast Cancer.

A Phase 2 study of Anatomic Stage IV Breast Cancer AJCC v8 and Metastatic Breast Carcinoma, sponsored by City of Hope Medical Center.

Recruiting
Registry status
Phase 2
Development phase
43
Enrollment target
3
Study locations

NCT04305834 is a Phase 2 study of Anatomic Stage IV Breast Cancer AJCC v8 and Metastatic Breast Carcinoma that is actively recruiting participants, run by City of Hope Medical Center. The registered enrollment target is 43 participants, below the 166-participant average among 59 other Anatomic Stage IV Breast Cancer AJCC v8 trials with a reported enrollment target (74% lower). The trial reports 3 study locations across 3 states.

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The verdict

NCT04305834, a Phase 2 study of Anatomic Stage IV Breast Cancer AJCC v8 and Metastatic Breast Carcinoma, is actively recruiting participants, sponsored by City of Hope Medical Center.

RECRUITING
Registry status
Phase 2
Development phase
43 participants
Enrollment target
3
Study locations

Study Summary

This phase IIa trial studies the side effects of abemaciclib monotherapy in treating patients age 70 years and older with hormone receptor positive, HER2 negative breast cancer that has spread to other places in the body.

Interventions

  • OTHER Questionnaire Administration
  • DRUG Abemaciclib

Study Locations (3)

California

  • City of Hope Medical Center - Duarte

Massachusetts

  • Dana Farber Cancer Institute - Boston

New York

  • Roswell Park Comprehensive Cancer Center - Buffalo

Trial Details

FieldValue
Enrollment Target 43 participants
Start Date 2020-03-25
Est. Completion 2026-08-21
Phase Phase 2

Sponsor

City of Hope Medical Center

582 total trials

What the Registry Record Tells You About NCT04305834

The ClinicalTrials.gov registry entry for NCT04305834 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 43 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 166-participant average among 59 other Anatomic Stage IV Breast Cancer AJCC v8 trials with a reported enrollment target (74% lower). The listed sponsor is City of Hope Medical Center, which has 582 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Anatomic Stage IV Breast Cancer AJCC v8 appearing as the primary indexed condition, and to 2 interventions - of which Questionnaire Administration is the first listed.

NCT04305834 reports 3 study locations spanning 3 distinct geographic areas - top geographies include California, Massachusetts, New York.

Frequently Asked Questions

What is clinical trial NCT04305834 about?

NCT04305834 is a clinical study titled "Abemaciclib and Endocrine Therapy in Older Patients With Breast Cancer.". This phase IIa trial studies the side effects of abemaciclib monotherapy in treating patients age 70 years and older with hormone receptor positive, HER2 negative breast cancer that has spread to other places in the body.

What is the current status of trial NCT04305834?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 43 participants. The study started on 2020-03-25. Estimated completion is 2026-08-21.

What conditions does trial NCT04305834 study?

This clinical trial studies the following conditions: Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma, Hormone Receptor-Positive Breast Carcinoma, Prognostic Stage IV Breast Cancer AJCC v8.

What interventions are being tested in trial NCT04305834?

The interventions under investigation include: Questionnaire Administration (OTHER), Abemaciclib (DRUG).

Who is sponsoring clinical trial NCT04305834?

This trial is sponsored by City of Hope Medical Center, which has 582 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04305834 being conducted?

This trial has 3 study locations across California, Massachusetts, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.