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ClinicalTrials.gov 10 recruiting now official registry

Post Traumatic Stress Disorder (PTSD) clinical trials

10 of 14 indexed Post Traumatic Stress Disorder (PTSD) trials are currently recruiting.

14 US clinical trials · 10 currently recruiting

Post Traumatic Stress Disorder (PTSD) is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 10 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 4 of these trials.

The research picture

Post Traumatic Stress Disorder (PTSD) has 14 registered US clinical trials, 10 of them open to new participants right now, about 71% of the total.

10
recruiting participants now
71%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
4
top sponsor: VA Office of Research and Development
Phase 12Phase 23Phase 41

Active & Recent Trials

14 total, page 1 of 1

RECRUITING NA 300 participants

Type I Hybrid Effectiveness-Implementation Trial of Primary Care Brief Mindfulness Training for Veterans

VA Office of Research and Development

NCT06162741

RECRUITING Phase 2 240 participants

Examining Intranasal Oxytocin Augmentation of Brief Couples Therapy for Veterans With PTSD

VA Office of Research and Development

NCT06194851

RECRUITING NA 200 participants

Shared Decision Making in PTSD Treatment

The University of Texas Health Science Center at San Antonio

NCT06953687

RECRUITING NA 146 participants

Neuromodulation + Prolonged Exposure Therapy: Evaluation of a Technology-Enhanced, Integrated Treatment for Pain and PTSD

The University of Texas Health Science Center, Houston

NCT07116109

RECRUITING NA 125 participants

Evaluating Treatments for Suicidal Veterans With PTSD

VA Office of Research and Development

NCT05974631

RECRUITING NA 125 participants

NightWare and Cardiovascular Health in Veterans With PTSD

VA Office of Research and Development

NCT06419959

RECRUITING Phase 4 90 participants

Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients

Texas Tech University Health Sciences Center

NCT06903819

RECRUITING Phase 2 76 participants

Suvorexant for Treatment of AUD and PTSD

Pharmacotherapies for Alcohol and Substance Use Disorders Alliance

NCT06679062

RECRUITING NA 40 participants

Targeted Accelerated TMS for Post-Traumatic Stress Disorder

Brigham and Women's Hospital

NCT07245641

RECRUITING Phase 1 10 participants

Effect of Sublingual Formulation of Dexmedetomidine Hydrochloride (HCl) (BXCL501) - Outpatient Study

Pharmacotherapies for Alcohol and Substance Use Disorders Alliance

NCT06335407

COMPLETED NA 66 participants

Occupational Therapy Driving Intervention for Returning Combat Veterans.

University of Florida

NCT02764983

COMPLETED NA 58 participants

Effectiveness of a Driving Intervention on Safe Community Mobility for Returning Combat Veterans

University of Florida

NCT02765672

COMPLETED Phase 2 24 participants

Zonisamide in Addition to E-CPT-C for Veterans With PTSD and Comorbid Alcohol Dependence

Yale University

NCT01847469

COMPLETED Phase 1 5 participants

A Clinical Trial for Post Traumatic Stress Disorder

Antonia New

NCT00554177

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 3
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Post Traumatic Stress Disorder (PTSD) Trial Landscape

14 indexed Post Traumatic Stress Disorder (PTSD) studies · 10 recruiting (71%).

Phase mix: 1 late (III/IV) vs 5 early (I/II).

Top sponsor: VA Office of Research and Development (4 trials), 8 others listed. 14 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Post Traumatic Stress Disorder (PTSD)?

PlainTrial tracks 14 US clinical trials for Post Traumatic Stress Disorder (PTSD), of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Post Traumatic Stress Disorder (PTSD)?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.