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ClinicalTrials.gov enrollment closed later-stage tilt small index

Pneumococcal Infections: later-stage trial registry

A small indexed set (11 trials) with no open enrollment listed right now.

Corpus placement: #1,577 of 28,707 conditions by registered trial count.

11 US clinical trials · none currently recruiting · #1,577 of 28,707 conditions by registered trial count

Pneumococcal Infections: 11 US clinical trials tracked, none currently recruiting.

Pneumococcal Infections is the subject of 11 registered US clinical trials on ClinicalTrials.gov, none currently recruiting. 7 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Merck Sharp & Dohme, running 6 of these trials.

Enrollment posture brief

Registry condition pneumococcal-infections

OPEN 0 | RECR 0% | LATE 7 | EARLY 2 | RANK #1577 | SPON 6

Nearest open-share peer: Accelerated Phase Chronic Myelogenous Leukemia (0% recruiting · 12 trials)

Acute Pancreatitis81.8%Acute Stroke45.5%Acquired Brain Injury36.4%Acute Lung Injury9.1%Pneumococcal Infections (thi…0%
Open-enrollment share among volume-matched conditions near Pneumococcal Infections

Pneumococcal Infections has no open enrollment in this registry pull (11 archived studies). Peers show how other volume-matched labels compare on open share. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Pneumococcal Infections on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Pneumococcal Infections is recruiting below its size-band peers.

    0 of 11 indexed trials (0%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Pneumococcal Infections research.

    Merck Sharp & Dohme accounts for 6 of 11 trials (54.5%). 5 distinct sponsors appear on at least one study for this condition label.

  3. Typical Pneumococcal Infections enrolment sits around 938 participants.

    Median target enrolment is 938 among the 11 trials that report a genuine target (sentinel values excluded). 1 of those (9.1%) plan for fewer than 100 participants.

  4. Pneumococcal Infections research is mostly interventional.

    10 interventional and 1 observational studies make up this index (90.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 21Phase 37

Indexed trials (enrollment closed)

11 total, page 1 of 1

ACTIVE NOT RECRUITING Phase 3 1,268 participants

Study of the Safety and Immunogenicity of Catch-up Vaccination With a 21-valent Pneumococcal Conjugate Vaccine (PCV21) in Healthy Infants, Toddlers, Children, and Adolescents

Sanofi Pasteur, a Sanofi Company

NCT06838000

COMPLETED Phase 3 1,515 participants

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 Followed by PNEUMOVAX™23 in Adults at Increased Risk for Pneumococcal Disease (V114-017/PNEU-DAY)

Merck Sharp & Dohme

NCT03547167

COMPLETED Phase 3 1,205 participants

Safety and Immunogenicity of V114 in Healthy Adults (V114-019/PNEU-AGE)

Merck Sharp & Dohme

NCT03950622

COMPLETED Phase 3 1,200 participants

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 When Administered Concomitantly With Influenza Vaccine in Healthy Adults 50 Years of Age or Older (V114-021/PNEU-FLU)

Merck Sharp & Dohme

NCT03615482

COMPLETED Phase 2 1,051 participants

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of Two Lots of V114 in Healthy Infants (V114-008)

Merck Sharp & Dohme

NCT02987972

COMPLETED Phase 3 938 participants

Study Evaluating The Safety, Tolerability And Immunogenicity Of A 13-Valent Pneumococcal Conjugate Vaccine (13vPnC)

Wyeth is now a wholly owned subsidiary of Pfizer

NCT00546572

COMPLETED Phase 3 900 participants

A Study to Evaluate the Interchangeability of V114 and Prevnar 13™ in Healthy Infants (V114-027/PNEU-DIRECTION)

Merck Sharp & Dohme

NCT03620162

COMPLETED 326 participants

Effects of MAC Preventive Therapy on Disease-Causing Bacteria in HIV-Infected Patients: A Substudy of CPCRA 048

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00000933

COMPLETED NA 300 participants

Pneumococcal Vaccine and Routine Pediatric Immunizations in HIV-Infected Children Receiving Anti-HIV Drugs

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00013871

COMPLETED Phase 3 277 participants

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 in Allogeneic Hematopoietic Stem Cell Transplant Recipients (V114-022/PNEU-STEM)

Merck Sharp & Dohme

NCT03565900

COMPLETED Phase 1 66 participants

A Phase 1, Randomized, Controlled, Observer-blinded Trial to Evaluate the Safety and Immunogenicity of a Multivalent Pneumococcal Conjugate Vaccine in Healthy Adults Aged 18 to 49 Years

Pfizer

NCT02955160

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 1
Phase 3 7

Named interventions

Most-linked intervention names on Pneumococcal Infections records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

V114 Biological
5 trials
Prevnar 13™ Biological
4 trials
PNEUMOVAX™23 Biological
2 trials
Recombivax HB™ Biological
1 trials
Pentacel™ Biological
1 trials
RotaTeq™ Biological
1 trials
Tdap Biological
1 trials
Multivalent Biological
1 trials

US sites by state

Facility locations filed on Pneumococcal Infections trials. A trial with sites in several states counts in each.

California 9 trials
Florida 8 trials
Colorado 6 trials
New York 5 trials
Illinois 5 trials
Georgia 5 trials
Alabama 5 trials
Texas 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Pneumococcal Infections page

11 registered trials, 0 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • No Pneumococcal Infections trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
  • Merck Sharp & Dohme sponsors the most Pneumococcal Infections trials on record, review their full trial history before evaluating a specific study. See Merck Sharp & Dohme's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Pneumococcal Infections condition card totals 11 registered trials; most-linked intervention V114; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.