Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
PFO - Patent Foramen Ovale clinical trials
3 of 3 indexed PFO - Patent Foramen Ovale trials are currently recruiting.
Corpus placement: #5,209 of 28,707 conditions by registered trial count.
3 US clinical trials · 3 currently recruiting · #5,209 of 28,707 conditions by registered trial count
PFO - Patent Foramen Ovale: 3 US clinical trials tracked, 3 recruiting.
PFO - Patent Foramen Ovale is the subject of 3 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. The most active sponsor is Recross Cardio, running 1 of these trials.
Enrollment posture brief
Registry condition pfo-patent-foramen-ovale
OPEN 3 | RECR 100% | LATE 0 | EARLY 0 | RANK #5209 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Aortic Arch Aneurysm (100% recruiting · 5 trials)
PFO - Patent Foramen Ovale lists 3 open slots (100% of 3 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for PFO - Patent Foramen Ovale on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
-
PFO - Patent Foramen Ovale is recruiting above its size-band peers.
3 of 3 indexed trials (100%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
Open and recent trials
3 total, page 1 of 1
Abbott Structural Heart Device Registry
Abbott Medical Devices
NCT06590467
GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study
W.L.Gore & Associates
NCT03821129
Early Feasibility Study (EFS) Evaluating Percutaneous Repair of the Atrial Septum With a Novel PFO Occluder: The PROTEA-PFO Study
Recross Cardio
NCT07172464
Phase Distribution
Phase data not available
Top Sponsors
Named interventions
Most-linked intervention names on PFO - Patent Foramen Ovale records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on PFO - Patent Foramen Ovale trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this PFO - Patent Foramen Ovale page
3 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 3 PFO - Patent Foramen Ovale trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Recross Cardio sponsors the most PFO - Patent Foramen Ovale trials on record, review their full trial history before evaluating a specific study. See Recross Cardio's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This PFO - Patent Foramen Ovale condition card totals 3 registered trials; most-linked intervention Recross P3 Occluder (P3O) System; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.