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ClinicalTrials.gov 4 recruiting now early-phase tilt

Peripheral Vascular Disease: early-phase trial registry

4 of 27 indexed Peripheral Vascular Disease trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #598 of 28,707 conditions by registered trial count.

27 US clinical trials · 4 currently recruiting · #598 of 28,707 conditions by registered trial count

Peripheral Vascular Disease: 27 US clinical trials tracked, 4 recruiting.

Peripheral Vascular Disease is the subject of 27 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is Northwestern University, running 4 of these trials.

Enrollment posture brief

Registry condition peripheral-vascular-disease

OPEN 4 | RECR 15% | LATE 2 | EARLY 8 | RANK #598 | SPON 4

Nearest open-share peer: Cerebrovascular Accident (15% recruiting · 27 trials)

Alopecia Areata55.6%Acute Ischemic Stroke44.4%Adenocarcinoma25.9%Acne22.2%Peripheral Vascular Dise (th…15%
Open-enrollment share among volume-matched conditions near Peripheral Vascular Disease

Peripheral Vascular Disease lists 4 open slots (15% of 27 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Peripheral Vascular Disease on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Peripheral Vascular Disease is recruiting below its size-band peers.

    4 of 27 indexed trials (14.8%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Peripheral Vascular Disease trials is spread across many organizations.

    Northwestern University accounts for 4 of 27 trials (14.8%). 22 distinct sponsors appear on at least one study for this condition label.

  3. Typical Peripheral Vascular Disease enrolment sits around 148 participants.

    Median target enrolment is 148 among the 26 trials that report a genuine target (sentinel values excluded). 11 of those (42.3%) plan for fewer than 100 participants.

  4. Peripheral Vascular Disease research is mostly interventional.

    25 interventional and 2 observational studies make up this index (92.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 15Phase 23Phase 32

Open and recent trials

27 total, page 1 of 1

RECRUITING Phase 3 386 participants

Improving Mobility After Revascularization in Peripheral Artery Disease

Northwestern University

NCT06686121

RECRUITING NA 32 participants

Far Red Light to Improve Functioning in PAD

Northwestern University

NCT06165016

RECRUITING NA 32 participants

ENhancing Exercise with LIGHT to Improve Functioning in PAD

Northwestern University

NCT06399900

RECRUITING NA 24 participants

Leg Exercise Assistive Paddling (LEAP) Therapy for Peripheral Artery Disease

University of Nebraska

NCT06389149

ACTIVE NOT RECRUITING Phase 1 40 participants

BGC101 (EnEPC) Autologous Cell Therapy From Patient's Own Blood for Treatment of Critical Limb Ischemia (CLI)

BioGenCell

NCT02805023

COMPLETED NA 2,512 participants

Project to Improve Communication About Serious Illness--Hospital Study: Pragmatic Trial (Trial 1)

University of Washington

NCT04281784

COMPLETED NA 1,014 participants

Femoral Arterial Access With Ultrasound Trial

University of California, Irvine

NCT00667381

COMPLETED 500 participants

Registry of AngioJet Use in the Peripheral Vascular System

Boston Scientific Corporation

NCT01086215

COMPLETED Phase 2 289 participants

Safety and Efficacy Study of Ad2/Hypoxia Inducible Factor (HIF)-1α/VP16 Gene Transfer in Patients With Intermittent Claudication

Genzyme, a Sanofi Company

NCT00117650

COMPLETED Phase 3 280 participants

Efficacy/Safety of Ecraprost in Lipid Emulsion for Treatment of Critical Leg Ischemia Due to Peripheral Arterial Disease

Tanabe Pharma Corporation

NCT00059657

COMPLETED NA 276 participants

A Multi-center Clinical Trial of the Misago™ Self-Expanding Stent System for Superficial Femoral Artery

Terumo Medical Corporation

NCT01118117

COMPLETED NA 257 participants

Evaluation of Safety and Efficacy of the FlexStent® Femoropopliteal Self-Expanding Stent System

Cordis US

NCT01355406

COMPLETED Phase 2 243 participants

PF-00489791 For The Treatment Of Raynaud's

Pfizer

NCT01090492

COMPLETED NA 170 participants

BARD® The VENOVO™ Venous Stent Study for Treatment of Iliofemoral Occlusive Disease

C. R. Bard

NCT02655887

COMPLETED 165 participants

RISE: A Clinical Evaluation of the StarClose™ Vascular Closure System

Abbott Medical Devices

NCT00736086

COMPLETED NA 155 participants

BARD® Study of LIFESTREAM™ Balloon Expandable Covered Stent Treating Iliac Arterial Occlusive Disease

C. R. Bard

NCT02228564

COMPLETED Phase 2 148 participants

Trial of VLTS-934 in Subjects With Intermittent Claudication Secondary to Peripheral Arterial Disease

Valentis

NCT00113009

COMPLETED NA 141 participants

Absolute Pro® MOMENTUM™

Abbott Medical Devices

NCT01444378

COMPLETED NA 112 participants

The OPC for Optimal Delivery of Paclitaxel for the Prevention of Endovascular Restenosis - Above and Below the Knee

Horizons International Peripheral Group

NCT02464501

COMPLETED NA 90 participants

Study Comparing Two Methods of Expanding Stents Placed in Legs of Diabetics With Peripheral Vascular Disease

North Texas Veterans Healthcare System

NCT00827853

COMPLETED Phase 1 81 participants

A Clinical and Histological Analysis of Mesenchymal Stem Cells in Amputation

Indiana University

NCT02685098

COMPLETED NA 30 participants

Guided Meditation to Decrease Perioperative Anxiety and Increase Patient Intraoperative Compliance in Vascular Surgery

Massachusetts General Hospital

NCT05837481

COMPLETED NA 29 participants

JetStream (JS) Atherectomy in Femoropopliteal In-Stent Restenotic Lesions

Midwest Cardiovascular Research Foundation

NCT01722877

COMPLETED NA 24 participants

Ischemic Preconditioning Claudication Study

Medical College of Wisconsin

NCT03511157

COMPLETED Phase 1 20 participants

ALD-301 for Critical Limb Ischemia, Randomized Trial

Aldagen

NCT00392509

COMPLETED Phase 1 10 participants

Stem Cell Injection for Peripheral Vascular Disease

Northwestern University

NCT00278603

COMPLETED Phase 1

Evaluation of the Effect of the Flowaid Device in Increasing Local Circulation in the Leg

Rosenblum, Jonathan I., DPM

NCT00538226

Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 3
Phase 3 2

Named interventions

Most-linked intervention names on Peripheral Vascular Disease records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Sham light therapy Device
2 trials
Far red light therapy Device
2 trials
cryoplasty balloon Procedure
1 trials
Conventional angioplasty balloon Procedure
1 trials
Real-time Ultrasound Guidance (Site-Rite 5 or 6 machine) Device
1 trials
PF-00489791 Drug
1 trials
ALDH-br bone marrow cells vs. mononuclear bone marrow cells Procedure
1 trials
VLTS-934 Drug
1 trials

US sites by state

Facility locations filed on Peripheral Vascular Disease trials. A trial with sites in several states counts in each.

California 13 trials
Illinois 11 trials
New York 8 trials
Michigan 8 trials
Georgia 8 trials
Florida 8 trials
Texas 7 trials
Iowa 7 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Peripheral Vascular Disease page

27 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 4 Peripheral Vascular Disease trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Northwestern University sponsors the most Peripheral Vascular Disease trials on record, review their full trial history before evaluating a specific study. See Northwestern University's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Peripheral Vascular Disease condition card totals 27 registered trials; most-linked intervention Sham light therapy; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.