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2026 data Public-data reference. official source

Peripheral Vascular Disease

Open-data reference.

26 US clinical trials · 4 currently recruiting

Active & Recent Trials

RECRUITING Phase 3 386 participants

Improving Mobility After Revascularization in Peripheral Artery Disease

Northwestern University

NCT06686121

RECRUITING NA 32 participants

Far Red Light to Improve Functioning in PAD

Northwestern University

NCT06165016

RECRUITING NA 32 participants

ENhancing Exercise with LIGHT to Improve Functioning in PAD

Northwestern University

NCT06399900

RECRUITING NA 24 participants

Leg Exercise Assistive Paddling (LEAP) Therapy for Peripheral Artery Disease

University of Nebraska

NCT06389149

ACTIVE NOT RECRUITING Phase 1 40 participants

BGC101 (EnEPC) Autologous Cell Therapy From Patient's Own Blood for Treatment of Critical Limb Ischemia (CLI)

BioGenCell

NCT02805023

COMPLETED NA 2,512 participants

Project to Improve Communication About Serious Illness--Hospital Study: Pragmatic Trial (Trial 1)

University of Washington

NCT04281784

COMPLETED NA 1,014 participants

Femoral Arterial Access With Ultrasound Trial

University of California, Irvine

NCT00667381

COMPLETED 500 participants

Registry of AngioJet Use in the Peripheral Vascular System

Boston Scientific Corporation

NCT01086215

COMPLETED Phase 2 289 participants

Safety and Efficacy Study of Ad2/Hypoxia Inducible Factor (HIF)-1α/VP16 Gene Transfer in Patients With Intermittent Claudication

Genzyme, a Sanofi Company

NCT00117650

COMPLETED Phase 3 280 participants

Efficacy/Safety of Ecraprost in Lipid Emulsion for Treatment of Critical Leg Ischemia Due to Peripheral Arterial Disease

Tanabe Pharma Corporation

NCT00059657

COMPLETED NA 276 participants

A Multi-center Clinical Trial of the Misago™ Self-Expanding Stent System for Superficial Femoral Artery

Terumo Medical Corporation

NCT01118117

COMPLETED NA 257 participants

Evaluation of Safety and Efficacy of the FlexStent® Femoropopliteal Self-Expanding Stent System

Cordis US

NCT01355406

COMPLETED Phase 2 243 participants

PF-00489791 For The Treatment Of Raynaud's

Pfizer

NCT01090492

COMPLETED NA 170 participants

BARD® The VENOVO™ Venous Stent Study for Treatment of Iliofemoral Occlusive Disease

C. R. Bard

NCT02655887

COMPLETED 165 participants

RISE: A Clinical Evaluation of the StarClose™ Vascular Closure System

Abbott Medical Devices

NCT00736086

COMPLETED NA 155 participants

BARD® Study of LIFESTREAM™ Balloon Expandable Covered Stent Treating Iliac Arterial Occlusive Disease

C. R. Bard

NCT02228564

COMPLETED Phase 2 148 participants

Trial of VLTS-934 in Subjects With Intermittent Claudication Secondary to Peripheral Arterial Disease

Valentis

NCT00113009

COMPLETED NA 141 participants

Absolute Pro® MOMENTUM™

Abbott Medical Devices

NCT01444378

COMPLETED NA 112 participants

The OPC for Optimal Delivery of Paclitaxel for the Prevention of Endovascular Restenosis - Above and Below the Knee

Horizons International Peripheral Group

NCT02464501

COMPLETED Phase 1 81 participants

A Clinical and Histological Analysis of Mesenchymal Stem Cells in Amputation

Indiana University

NCT02685098

COMPLETED NA 30 participants

Guided Meditation to Decrease Perioperative Anxiety and Increase Patient Intraoperative Compliance in Vascular Surgery

Massachusetts General Hospital

NCT05837481

COMPLETED NA 29 participants

JetStream (JS) Atherectomy in Femoropopliteal In-Stent Restenotic Lesions

Midwest Cardiovascular Research Foundation

NCT01722877

COMPLETED NA 24 participants

Ischemic Preconditioning Claudication Study

Medical College of Wisconsin

NCT03511157

COMPLETED Phase 1 20 participants

ALD-301 for Critical Limb Ischemia, Randomized Trial

Aldagen

NCT00392509

COMPLETED Phase 1 10 participants

Stem Cell Injection for Peripheral Vascular Disease

Northwestern University

NCT00278603

COMPLETED Phase 1

Evaluation of the Effect of the Flowaid Device in Increasing Local Circulation in the Leg

Rosenblum, Jonathan I., DPM

NCT00538226

Phase Distribution

PhaseTrial count
Early Phase 1 5
Phase 2 3
Phase 3 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Peripheral Vascular Disease Trial Landscape

ClinicalTrials.gov lists 26 US studies indexed under Peripheral Vascular Disease, and 4 of those are currently open to recruitment — roughly 15% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Peripheral Vascular Disease shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 8 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Peripheral Vascular Disease is led by Northwestern University with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 26 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Peripheral Vascular Disease?

PlainTrial tracks 26 US clinical trials for Peripheral Vascular Disease, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Peripheral Vascular Disease?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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