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ClinicalTrials.gov 8 recruiting now official registry

Peripheral Neuropathy clinical trials

Every US clinical trial registered for Peripheral Neuropathy — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

28 US clinical trials · 8 currently recruiting

The research picture

Peripheral Neuropathy has 28 registered US clinical trials, 8 of them open to new participants right now — about 29% of the total.

8
recruiting participants now
29%
of trials open to enrollment
4
in Phase 3–4 (later-stage)
3
top sponsor: M.D. Anderson Cancer Center

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING NA 180 participants

DoD AtMS for Posttraumatic Peripheral Neuropathic Pain

Veterans Medical Research Foundation

NCT07301177

RECRUITING 150 participants

Investigational Use of Neuromuscular Ultrasound

National Institute of Neurological Disorders and Stroke (NINDS)

NCT05237973

RECRUITING NA 60 participants

Reliability of Force Measurement Within the Carbon Fiber Orthosis Proximal Cuff

University of Iowa

NCT06127264

RECRUITING 40 participants

A Causative Role for Amylin in Diabetic Peripheral Neuropathy

Zabeen Mahuwala, MD

NCT03481283

RECRUITING NA 38 participants

Innovative Treatment of Chemotherapy-Induced Painful Peripheral Neuropathy in Adolescents and Young Adults With Cancer: A Two Arm Pilot Study

M.D. Anderson Cancer Center

NCT05357469

RECRUITING NA 30 participants

Intermittent Dosing of Dorsal Root Ganglion Stimulation as an Alternate Paradigm to Continuous Low-Frequency Therapy

Rush University Medical Center

NCT04909138

RECRUITING 20 participants

A Prospective Natural History and Outcome Measure Discovery Study of Charcot-Marie-Tooth Disease, Type 4J

Elpida Therapeutics SPC

NCT06151600

RECRUITING NA 10 participants

Replexa+ Shortwave Diathermy Device for Patients Diagnosed With Peripheral Artery Disease and Peripheral Neuropathy

Indiana University

NCT07336381

ACTIVE NOT RECRUITING NA 185 participants

Clinical Study of a Micro-Implantable Pulse Generator for the Treatment of Peripheral Neuropathic Pain (COMFORT 2)

Nalu Medical

NCT05870124

ACTIVE NOT RECRUITING NA 90 participants

Massage Therapy in Reducing Chemotherapy-Induced Peripheral Neuropathy in Patients With Gastrointestinal or Breast Malignancies

M.D. Anderson Cancer Center

NCT02221700

ACTIVE NOT RECRUITING 80 participants

Effects of Neurofeedback on Neural Function, Neuromodulation, and Chemotherapy-Induced Neuropathic Pain

M.D. Anderson Cancer Center

NCT01278225

ACTIVE NOT RECRUITING NA 61 participants

Axon Therapy for Post-Traumatic Peripheral Neuropathic Pain Compared to Conventional Medical Management

NeuraLace Medical

NCT04795635

ACTIVE NOT RECRUITING NA 20 participants

Clinical Trial to Assess the Safety of a Novel Scaffold Biomaterial

Mayo Clinic

NCT03584022

COMPLETED Phase 3 250 participants

Glutamic Acid in Reducing Nerve Damage Caused by Vincristine in Young Patients With Cancer

University of South Florida

NCT00369564

COMPLETED Phase 3 231 participants

Duloxetine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer

Alliance for Clinical Trials in Oncology

NCT00489411

COMPLETED Phase 3 220 participants

Open Label Safety And Efficacy Study Of Pregabalin In Subjects With Nerve Pain Asociated With Human Immunodeficiency Virus (HIV) Neuropathy

Pfizer's Upjohn has merged with Mylan to form Viatris

NCT00264875

COMPLETED 110 participants

Serum Vitamin D Levels and Peripheral Neuropathy Among Multiple Myeloma Patients

Oncotherapeutics

NCT01697839

COMPLETED 62 participants

StimRouter Registry Clinical Protocol

Bioness

NCT03913689

COMPLETED Phase 4 62 participants

A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions

Endo Pharmaceuticals

NCT00904202

COMPLETED NA 46 participants

Lower Extremity Splinting to Manage Pain and Sleep Disturbances Associated With HIV/AIDS Related Peripheral Neuropathy

Texas Woman's University

NCT01419314

COMPLETED Phase 2 46 participants

Pregabalin in Preventing Acute Pain Syndrome in Patients Receiving Paclitaxel

Academic and Community Cancer Research United

NCT01637077

COMPLETED NA 44 participants

Distal Peripheral Neuropathy in Type 2 Diabetes

New York University

NCT05104047

COMPLETED NA 43 participants

Effect of Weight-Bearing Exercise on People With Diabetes and Neuropathic Feet

Washington University School of Medicine

NCT00763087

COMPLETED NA 39 participants

Electrical Stimulation Pain Therapy in Treating Chronic Pain and Numbness Caused By Chemotherapy in Patients With Cancer

Virginia Commonwealth University

NCT01196442

COMPLETED NA 28 participants

Acupuncture to Reduce Chemotherapy-induced Peripheral Neuropathy Severity During Neoadjuvant or Adjuvant Weekly Paclitaxel Chemotherapy in Breast Cancer Patients

Memorial Sloan Kettering Cancer Center

NCT02364726

COMPLETED NA 10 participants

Exercise and Oxaliplatin-induced Peripheral Neuropathy

Dartmouth-Hitchcock Medical Center

NCT05916118

COMPLETED Phase 2 8 participants

Pilot Study to Determine Effects of Salsalate in Type 1 Diabetes and Painful Peripheral Neuropathy

University of Michigan

NCT01480297

COMPLETED NA 3 participants

Peak Plantar Pressures While Wearing a Carbon Fiber Off Loading Orthoses

Washington University School of Medicine

NCT03618628

Phase Distribution

PhaseTrial count
Phase 2 2
Phase 3 3
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Peripheral Neuropathy Trial Landscape

ClinicalTrials.gov lists 28 US studies indexed under Peripheral Neuropathy, and 8 of those are currently open to recruitment — roughly 29% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Peripheral Neuropathy shows 4 late-stage studies (Phase 3 and Phase 4 combined) alongside 2 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Peripheral Neuropathy is led by M.D. Anderson Cancer Center with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 28 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Peripheral Neuropathy?

PlainTrial tracks 28 US clinical trials for Peripheral Neuropathy, of which 8 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Peripheral Neuropathy?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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