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ClinicalTrials.gov 8 recruiting now later-stage tilt

Peripheral Neuropathy: later-stage trial registry

8 of 28 indexed Peripheral Neuropathy trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #577 of 28,707 conditions by registered trial count.

28 US clinical trials · 8 currently recruiting · #577 of 28,707 conditions by registered trial count

Peripheral Neuropathy: 28 US clinical trials tracked, 8 recruiting.

Peripheral Neuropathy is the subject of 28 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 3 of these trials.

Enrollment posture brief

Registry condition peripheral-neuropathy

OPEN 8 | RECR 29% | LATE 4 | EARLY 2 | RANK #577 | SPON 3

Nearest open-share peer: Acne Scars (29% recruiting · 7 trials)

Peripheral Neuropathy (this)29%Anatomic Stage IB Breast Can25%Carcinoma, Hepatocellular25%Autistic Disorder17.9%Cocaine-Related Disorders0%
Open-enrollment share among volume-matched conditions near Peripheral Neuropathy

Peripheral Neuropathy lists 8 open slots (29% of 28 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Peripheral Neuropathy on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Peripheral Neuropathy is recruiting below its size-band peers.

    8 of 28 indexed trials (28.6%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Peripheral Neuropathy trials is spread across many organizations.

    M.D. Anderson Cancer Center accounts for 3 of 28 trials (10.7%). 25 distinct sponsors appear on at least one study for this condition label.

  3. Most Peripheral Neuropathy trials plan to enrol fewer than 100 people.

    Median target enrolment is 46 among the 28 trials that report a genuine target (sentinel values excluded). 21 of those (75%) plan for fewer than 100 participants.

  4. Peripheral Neuropathy research is mostly interventional.

    22 interventional and 6 observational studies make up this index (78.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 22Phase 33Phase 41

Open and recent trials

28 total, page 1 of 1

RECRUITING NA 180 participants

DoD AtMS for Posttraumatic Peripheral Neuropathic Pain

Veterans Medical Research Foundation

NCT07301177

RECRUITING 150 participants

Investigational Use of Neuromuscular Ultrasound

National Institute of Neurological Disorders and Stroke (NINDS)

NCT05237973

RECRUITING NA 60 participants

Reliability of Force Measurement Within the Carbon Fiber Orthosis Proximal Cuff

University of Iowa

NCT06127264

RECRUITING 40 participants

A Causative Role for Amylin in Diabetic Peripheral Neuropathy

Zabeen Mahuwala, MD

NCT03481283

RECRUITING NA 38 participants

Innovative Treatment of Chemotherapy-Induced Painful Peripheral Neuropathy in Adolescents and Young Adults With Cancer: A Two Arm Pilot Study

M.D. Anderson Cancer Center

NCT05357469

RECRUITING NA 30 participants

Intermittent Dosing of Dorsal Root Ganglion Stimulation as an Alternate Paradigm to Continuous Low-Frequency Therapy

Rush University Medical Center

NCT04909138

RECRUITING 20 participants

A Prospective Natural History and Outcome Measure Discovery Study of Charcot-Marie-Tooth Disease, Type 4J

Elpida Therapeutics SPC

NCT06151600

RECRUITING NA 10 participants

Replexa+ Shortwave Diathermy Device for Patients Diagnosed With Peripheral Artery Disease and Peripheral Neuropathy

Indiana University

NCT07336381

ACTIVE NOT RECRUITING NA 185 participants

Clinical Study of a Micro-Implantable Pulse Generator for the Treatment of Peripheral Neuropathic Pain (COMFORT 2)

Nalu Medical

NCT05870124

ACTIVE NOT RECRUITING NA 90 participants

Massage Therapy in Reducing Chemotherapy-Induced Peripheral Neuropathy in Patients With Gastrointestinal or Breast Malignancies

M.D. Anderson Cancer Center

NCT02221700

ACTIVE NOT RECRUITING 80 participants

Effects of Neurofeedback on Neural Function, Neuromodulation, and Chemotherapy-Induced Neuropathic Pain

M.D. Anderson Cancer Center

NCT01278225

ACTIVE NOT RECRUITING NA 61 participants

Axon Therapy for Post-Traumatic Peripheral Neuropathic Pain Compared to Conventional Medical Management

NeuraLace Medical

NCT04795635

ACTIVE NOT RECRUITING NA 20 participants

Clinical Trial to Assess the Safety of a Novel Scaffold Biomaterial

Mayo Clinic

NCT03584022

COMPLETED Phase 3 250 participants

Glutamic Acid in Reducing Nerve Damage Caused by Vincristine in Young Patients With Cancer

University of South Florida

NCT00369564

COMPLETED Phase 3 231 participants

Duloxetine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer

Alliance for Clinical Trials in Oncology

NCT00489411

COMPLETED Phase 3 220 participants

Open Label Safety And Efficacy Study Of Pregabalin In Subjects With Nerve Pain Asociated With Human Immunodeficiency Virus (HIV) Neuropathy

Pfizer's Upjohn has merged with Mylan to form Viatris

NCT00264875

COMPLETED 110 participants

Serum Vitamin D Levels and Peripheral Neuropathy Among Multiple Myeloma Patients

Oncotherapeutics

NCT01697839

COMPLETED 62 participants

StimRouter Registry Clinical Protocol

Bioness

NCT03913689

COMPLETED Phase 4 62 participants

A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions

Endo Pharmaceuticals

NCT00904202

COMPLETED NA 46 participants

Lower Extremity Splinting to Manage Pain and Sleep Disturbances Associated With HIV/AIDS Related Peripheral Neuropathy

Texas Woman's University

NCT01419314

COMPLETED Phase 2 46 participants

Pregabalin in Preventing Acute Pain Syndrome in Patients Receiving Paclitaxel

Academic and Community Cancer Research United

NCT01637077

COMPLETED NA 44 participants

Distal Peripheral Neuropathy in Type 2 Diabetes

New York University

NCT05104047

COMPLETED NA 43 participants

Effect of Weight-Bearing Exercise on People With Diabetes and Neuropathic Feet

Washington University School of Medicine

NCT00763087

COMPLETED NA 39 participants

Electrical Stimulation Pain Therapy in Treating Chronic Pain and Numbness Caused By Chemotherapy in Patients With Cancer

Virginia Commonwealth University

NCT01196442

COMPLETED NA 28 participants

Acupuncture to Reduce Chemotherapy-induced Peripheral Neuropathy Severity During Neoadjuvant or Adjuvant Weekly Paclitaxel Chemotherapy in Breast Cancer Patients

Memorial Sloan Kettering Cancer Center

NCT02364726

COMPLETED NA 10 participants

Exercise and Oxaliplatin-induced Peripheral Neuropathy

Dartmouth-Hitchcock Medical Center

NCT05916118

COMPLETED Phase 2 8 participants

Pilot Study to Determine Effects of Salsalate in Type 1 Diabetes and Painful Peripheral Neuropathy

University of Michigan

NCT01480297

COMPLETED NA 3 participants

Peak Plantar Pressures While Wearing a Carbon Fiber Off Loading Orthoses

Washington University School of Medicine

NCT03618628

Phase Distribution

PhaseTrial count
Phase 2 2
Phase 3 3
Phase 4 1

Named interventions

Most-linked intervention names on Peripheral Neuropathy records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

pregabalin Drug
2 trials
questionnaire administration Other
2 trials
placebo Other
2 trials
Carbon Fiber Off Loading Orthosis (CFO) Device
1 trials
glutamic acid Drug
1 trials
Placebo Moxibustion Other
1 trials
Moxibustion - Smokeless - (Active) Other
1 trials
Moxibustion - Traditional (Active) Other
1 trials

US sites by state

Facility locations filed on Peripheral Neuropathy trials. A trial with sites in several states counts in each.

California 7 trials
Texas 6 trials
Florida 4 trials
New York 3 trials
New Jersey 3 trials
North Carolina 3 trials
Minnesota 3 trials
Michigan 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Peripheral Neuropathy page

28 registered trials, 8 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Peripheral Neuropathy condition card totals 28 registered trials; most-linked intervention pregabalin; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.