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2026 data Public-data reference. official source

Ovarian High Grade Serous Adenocarcinoma

Open-data reference.

11 US clinical trials · 2 currently recruiting

Active & Recent Trials

RECRUITING Phase 3 880 participants

Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

NRG Oncology

NCT06580314

RECRUITING Phase 2 28 participants

Repurposing Atovaquone for the Treatment of Platinum-Resistant Ovarian Cancer

Emory University

NCT05998135

ACTIVE NOT RECRUITING Phase 2 444 participants

Pegylated Liposomal Doxorubicin Hydrochloride With Atezolizumab and/or Bevacizumab in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

National Cancer Institute (NCI)

NCT02839707

ACTIVE NOT RECRUITING Phase 1 155 participants

Cediranib Maleate and Olaparib in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Peritoneal Cancer or Recurrent Triple-Negative Breast Cancer

National Cancer Institute (NCI)

NCT01116648

ACTIVE NOT RECRUITING Phase 2 96 participants

Bevacizumab and Anetumab Ravtansine or Paclitaxel in Treating Patients With Refractory Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

National Cancer Institute (NCI)

NCT03587311

ACTIVE NOT RECRUITING Phase 2 70 participants

Testing the Combination of the Study Drugs Cediranib and Olaparib in Recurrent Ovarian Cancer

National Cancer Institute (NCI)

NCT02345265

ACTIVE NOT RECRUITING Phase 2 61 participants

Testing the Addition of an Immunotherapy Drug, Tremelimumab, to the PARP Inhibition Drug, Olaparib, for Recurrent Ovarian, Fallopian Tube or Peritoneal Cancer

National Cancer Institute (NCI)

NCT04034927

ACTIVE NOT RECRUITING Early Phase 1 38 participants

Adavosertib Before Surgery in Treating Patients With Advanced High Grade Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

M.D. Anderson Cancer Center

NCT02659241

ACTIVE NOT RECRUITING Phase 1 35 participants

Carboplatin, Gemcitabine Hydrochloride, and Berzosertib in Treating Patients With Recurrent and Metastatic Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

National Cancer Institute (NCI)

NCT02627443

ACTIVE NOT RECRUITING Phase 1 25 participants

Testing the Addition of Ipatasertib to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) for Stage III or IV Epithelial Ovarian Cancer

National Cancer Institute (NCI)

NCT05276973

ACTIVE NOT RECRUITING Phase 1 14 participants

Testing the Addition of an Anti-cancer Drug, Elimusertib (BAY 1895344) ATR Inhibitor, to the Chemotherapy Treatment (Gemcitabine) for Advanced Pancreatic and Ovarian Cancer, and Advanced Solid Tumors

National Cancer Institute (NCI)

NCT04616534

Phase Distribution

PhaseTrial count
Early Phase 1 5
Phase 2 5
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Ovarian High Grade Serous Adenocarcinoma Trial Landscape

ClinicalTrials.gov lists 11 US studies indexed under Ovarian High Grade Serous Adenocarcinoma, and 2 of those are currently open to recruitment — roughly 18% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Ovarian High Grade Serous Adenocarcinoma shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 10 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Ovarian High Grade Serous Adenocarcinoma is led by National Cancer Institute (NCI) with 8 indexed trials, alongside 3 other organizations in the top contributor list. The list on this page surfaces up to 11 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Ovarian High Grade Serous Adenocarcinoma?

PlainTrial tracks 11 US clinical trials for Ovarian High Grade Serous Adenocarcinoma, of which 2 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Ovarian High Grade Serous Adenocarcinoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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