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ClinicalTrials.gov 2 recruiting now full pipeline small index

Non-squamous Non-small Cell Lung Cancer: full-pipeline trial registry

2 of 10 indexed Non-squamous Non-small Cell Lung Cancer trials are currently recruiting.

Corpus placement: #1,724 of 28,707 conditions by registered trial count.

10 US clinical trials · 2 currently recruiting · #1,724 of 28,707 conditions by registered trial count

Non-squamous Non-small Cell Lung Cancer: 10 US clinical trials tracked, 2 recruiting.

Non-squamous Non-small Cell Lung Cancer is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Hoffmann-La Roche, running 2 of these trials.

Enrollment posture brief

Registry condition non-squamous-non-small-cell-lung-cancer

OPEN 2 | RECR 20% | LATE 5 | EARLY 4 | RANK #1724 | SPON 2

Nearest open-share peer: Acral Lentiginous Melanoma (20% recruiting · 5 trials)

Acute Leukemia of Ambiguous 80%Achondroplasia40%Accelerated Phase Chronic My20%Accidental Fall20%Non-squamous Non-small C (th…20%
Open-enrollment share among volume-matched conditions near Non-squamous Non-small Cell Lung Cancer

Non-squamous Non-small Cell Lung Cancer lists 2 open slots (20% of 10 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Non-squamous Non-small Cell Lung Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Non-squamous Non-small Cell Lung Cancer is recruiting below its size-band peers.

    2 of 10 indexed trials (20%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Non-squamous Non-small Cell Lung Cancer research.

    Hoffmann-La Roche accounts for 2 of 10 trials (20%). 9 distinct sponsors appear on at least one study for this condition label.

  3. Typical Non-squamous Non-small Cell Lung Cancer enrolment sits around 420 participants.

    Median target enrolment is 420 among the 10 trials that report a genuine target (sentinel values excluded). 3 of those (30%) plan for fewer than 100 participants.

  4. Non-squamous Non-small Cell Lung Cancer research is mostly interventional.

    9 interventional and 1 observational studies make up this index (90% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 23Phase 35

Open and recent trials

10 total, page 1 of 1

RECRUITING Phase 3 878 participants

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Metastatic Non-squamous NSCLC

AstraZeneca

NCT06627647

RECRUITING Phase 2 854 participants

A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination With Osimertinib as First-Line Treatment in Adult Participants With Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

AbbVie

NCT07005102

ACTIVE NOT RECRUITING Phase 3 586 participants

HERTHENA-Lung02: A Study of Patritumab Deruxtecan Versus Platinum-based Chemotherapy in Metastatic or Locally Advanced EGFRm NSCLC After Failure of EGFR TKI Therapy

Daiichi Sankyo

NCT05338970

ACTIVE NOT RECRUITING Phase 3 420 participants

Phase III Study of AK112 for NSCLC Patients

Summit Therapeutics

NCT06396065

ACTIVE NOT RECRUITING Phase 2 169 participants

Study Evaluating Effectiveness and Safety of Zimberelimab and Domvanalimab in Lung Cancer

Arcus Biosciences

NCT04736173

ACTIVE NOT RECRUITING Phase 2 29 participants

Tiragolumab With Atezolizumab Plus Bevacizumab in Previously-Treated Advanced Non-squamous NSCLC

Georgetown University

NCT04958811

COMPLETED Phase 3 485 participants

A Study of Bevacizumab in Combination With Standard of Care Treatment in Participants With Advanced Non-squamous Non-small Cell Lung Cancer (NSCLC)

Hoffmann-La Roche

NCT01351415

COMPLETED 110 participants

Real-World Effectiveness of Afatinib (Gilotrif) Following Immunotherapy in the Treatment of Metastatic, Squamous Cell Carcinoma of the Lung: A Multi-Site Retrospective Chart Review Study in the U.S.

Boehringer Ingelheim

NCT04750824

COMPLETED Phase 1 41 participants

A Study to Evaluate the Safety and Pharmacology of DNIB0600A in Participants With Platinum-Sensitive Ovarian Cancer or Non-Squamous Non-small Cell Lung Cancer

Genentech

NCT01995188

COMPLETED Phase 3 10 participants

A Study of Onartuzumab in Combination With Erlotinib in Patients With MET-Positive Stage IIIB or IV Non-Small Cell Lung Cancer Carrying an Activating Epidermal Growth Factor Receptor (EGFR) Mutation

Hoffmann-La Roche

NCT01887886

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 3
Phase 3 5

Top Sponsors

Daiichi Sankyo 1 trials
AbbVie 1 trials
AstraZeneca 1 trials
Genentech 1 trials

Named interventions

Most-linked intervention names on Non-squamous Non-small Cell Lung Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Carboplatin Drug
4 trials
Pemetrexed Drug
3 trials
Bevacizumab Drug
3 trials
Cisplatin Drug
2 trials
DNIB0600A Drug
1 trials
onartuzumab Drug
1 trials
other systemic therapy Drug
1 trials
erlotinib Drug
1 trials

US sites by state

Facility locations filed on Non-squamous Non-small Cell Lung Cancer trials. A trial with sites in several states counts in each.

Florida 6 trials
California 6 trials
Texas 3 trials
Tennessee 3 trials
Georgia 3 trials
Colorado 3 trials
Virginia 2 trials
Ohio 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Non-squamous Non-small Cell Lung Cancer page

10 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 2 Non-squamous Non-small Cell Lung Cancer trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Hoffmann-La Roche sponsors the most Non-squamous Non-small Cell Lung Cancer trials on record, review their full trial history before evaluating a specific study. See Hoffmann-La Roche's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Non-squamous Non-small Cell Lung Cancer condition card totals 10 registered trials; most-linked intervention Carboplatin; top US site state Florida. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.