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ClinicalTrials.gov enrollment closed early-phase tilt small index

Metastatic Rectal Adenocarcinoma: early-phase trial registry

A small indexed set (7 trials) with no open enrollment listed right now.

Corpus placement: #2,497 of 28,707 conditions by registered trial count.

7 US clinical trials · none currently recruiting · #2,497 of 28,707 conditions by registered trial count

Metastatic Rectal Adenocarcinoma: 7 US clinical trials tracked, none currently recruiting.

Metastatic Rectal Adenocarcinoma is the subject of 7 registered US clinical trials on ClinicalTrials.gov, none currently recruiting. 0 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 4 of these trials.

Enrollment posture brief

Registry condition metastatic-rectal-adenocarcinoma

OPEN 0 | RECR 0% | LATE 0 | EARLY 6 | RANK #2497 | SPON 4

Nearest open-share peer: Accelerated Phase Chronic Myelogenous Leukemia (0% recruiting · 12 trials)

ACL Tear71.4%ACL57.1%Acute Myelogenous Leukemia42.9%Acne Scars28.6%Metastatic Rectal Adenoc (th…0%
Open-enrollment share among volume-matched conditions near Metastatic Rectal Adenocarcinoma

Metastatic Rectal Adenocarcinoma has no open enrollment in this registry pull (7 archived studies). Peers show how other volume-matched labels compare on open share. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Metastatic Rectal Adenocarcinoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Metastatic Rectal Adenocarcinoma is recruiting below its size-band peers.

    0 of 7 indexed trials (0%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Metastatic Rectal Adenocarcinoma research.

    M.D. Anderson Cancer Center accounts for 4 of 7 trials (57.1%). 4 distinct sponsors appear on at least one study for this condition label.

  3. Most Metastatic Rectal Adenocarcinoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 46 among the 7 trials that report a genuine target (sentinel values excluded). 6 of those (85.7%) plan for fewer than 100 participants.

  4. Metastatic Rectal Adenocarcinoma research is mostly interventional.

    6 interventional and 1 observational studies make up this index (85.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14Phase 22

Indexed trials (enrollment closed)

7 total, page 1 of 1

ACTIVE NOT RECRUITING 341 participants

Circulating Tumor Cells in Patients With Locally Advanced Rectal Cancer

M.D. Anderson Cancer Center

NCT02874885

ACTIVE NOT RECRUITING Phase 2 84 participants

Testing the Addition of Nivolumab to Standard Treatment for Patients With Metastatic or Unresectable Colorectal Cancer That Have a BRAF Mutation

National Cancer Institute (NCI)

NCT05308446

ACTIVE NOT RECRUITING Phase 1 51 participants

SX-682 and Nivolumab for the Treatment of RAS-Mutated, MSS Unresectable or Metastatic Colorectal Cancer, the STOPTRAFFIC-1 Trial

M.D. Anderson Cancer Center

NCT04599140

ACTIVE NOT RECRUITING Phase 1 46 participants

LY3214996 and Cetuximab Alone or in Combination With Abemaciclib for the Treatment of Unresectable or Metastatic Colorectal Cancer

M.D. Anderson Cancer Center

NCT04616183

ACTIVE NOT RECRUITING Phase 1 38 participants

Encorafenib, Cetuximab, and Nivolumab in Treating Patients With Microsatellite Stable, BRAFV600E Mutated Unresectable or Metastatic Colorectal Cancer

M.D. Anderson Cancer Center

NCT04017650

ACTIVE NOT RECRUITING Phase 1 20 participants

FOLFOX and Bevacizumab in Combination With Botensilimab and Balstilimab (3B-FOLFOX) for the Treatment of Microsatellite Stable (MSS) Metastatic Colorectal Cancer

City of Hope Medical Center

NCT05627635

ACTIVE NOT RECRUITING Phase 2 12 participants

Panitumumab, Regorafenib, or TAS-102, in Treating Patients With Metastatic and/or Unresectable RAS Wild-Type Colorectal Cancer

Academic and Community Cancer Research United

NCT03992456

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 2

Named interventions

Most-linked intervention names on Metastatic Rectal Adenocarcinoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Nivolumab Biological
3 trials
Cetuximab Biological
3 trials
Encorafenib Drug
2 trials
Biospecimen Collection Procedure
2 trials
ERK1/2 Inhibitor LY3214996 Drug
1 trials
Trifluridine and Tipiracil Hydrochloride Drug
1 trials
Balstilimab Biological
1 trials
CXCR1/2 Inhibitor SX-682 Drug
1 trials

US sites by state

Facility locations filed on Metastatic Rectal Adenocarcinoma trials. A trial with sites in several states counts in each.

Texas 5 trials
California 3 trials
Arizona 2 trials
Wisconsin 1 trials
Pennsylvania 1 trials
New Jersey 1 trials
North Carolina 1 trials
Minnesota 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Metastatic Rectal Adenocarcinoma page

7 registered trials, 0 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • No Metastatic Rectal Adenocarcinoma trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
  • M.D. Anderson Cancer Center sponsors the most Metastatic Rectal Adenocarcinoma trials on record, review their full trial history before evaluating a specific study. See M.D. Anderson Cancer Center's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Metastatic Rectal Adenocarcinoma condition card totals 7 registered trials; most-linked intervention Nivolumab; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.