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ClinicalTrials.gov 6 recruiting now early-phase tilt small index

Malignant Digestive System Neoplasm: early-phase trial registry

6 of 12 indexed Malignant Digestive System Neoplasm trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,429 of 28,707 conditions by registered trial count.

12 US clinical trials · 6 currently recruiting · #1,429 of 28,707 conditions by registered trial count

Malignant Digestive System Neoplasm: 12 US clinical trials tracked, 6 recruiting.

Malignant Digestive System Neoplasm is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 5 of these trials.

Enrollment posture brief

Registry condition malignant-digestive-system-neoplasm

OPEN 6 | RECR 50% | LATE 0 | EARLY 5 | RANK #1429 | SPON 5

Nearest open-share peer: Abdominal Aortic Aneurysms (50% recruiting · 6 trials)

Malignant Digestive Syst (th…50%Acute Myeloid Leukemia in Re41.7%Adenocarcinoma of the Rectum41.7%Adherence, Patient16.7%Accelerated Phase Chronic My0%
Open-enrollment share among volume-matched conditions near Malignant Digestive System Neoplasm

Malignant Digestive System Neoplasm lists 6 open slots (50% of 12 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Malignant Digestive System Neoplasm on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Malignant Digestive System Neoplasm is recruiting above its size-band peers.

    6 of 12 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Malignant Digestive System Neoplasm research.

    M.D. Anderson Cancer Center accounts for 5 of 12 trials (41.7%). 8 distinct sponsors appear on at least one study for this condition label.

  3. Typical Malignant Digestive System Neoplasm enrolment sits around 90 participants.

    Median target enrolment is 90 among the 12 trials that report a genuine target (sentinel values excluded). 7 of those (58.3%) plan for fewer than 100 participants.

  4. Malignant Digestive System Neoplasm splits between interventional and observational designs.

    8 interventional and 4 observational studies make up this index (66.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 23

Open and recent trials

12 total, page 1 of 1

RECRUITING 5,000 participants

Data Collection for the Assessment of Acute and Late Normal Tissue in Patients Treated With Proton Therapy

M.D. Anderson Cancer Center

NCT00991094

RECRUITING 1,500 participants

Molecular Epidemiology of Biliary Tree Cancers

M.D. Anderson Cancer Center

NCT05179486

RECRUITING 500 participants

Surgical Thromboprophylaxis Practices in Oncology Patients Within the NCORP Network, STOP-VTE Study

Wake Forest University Health Sciences

NCT07215624

RECRUITING 150 participants

Evaluation of Portal Vein Stenting in Patients With Portal Vein Stenosis and Gastrointestinal Cancers

M.D. Anderson Cancer Center

NCT04629677

RECRUITING Phase 2 60 participants

2 Versus 6 Hour Oxaliplatin Infusions in Patients With Gastrointestinal Cancers

Emory University

NCT03800693

RECRUITING Phase 2 34 participants

Fucoidan for Preventing Chemotherapy-Related Fatigue in Patients With Gastrointestinal or Gynecological Cancer

Mayo Clinic

NCT06855524

ACTIVE NOT RECRUITING NA 134 participants

Perioperative Telemonitoring to Optimize Cancer Care and Outcomes

City of Hope Medical Center

NCT04986566

ACTIVE NOT RECRUITING NA 90 participants

Massage Therapy in Reducing Chemotherapy-Induced Peripheral Neuropathy in Patients With Gastrointestinal or Breast Malignancies

M.D. Anderson Cancer Center

NCT02221700

ACTIVE NOT RECRUITING Phase 2 60 participants

Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients With Spine Metastases at Risk for Compressing the Spinal Cord

M.D. Anderson Cancer Center

NCT02713269

ACTIVE NOT RECRUITING Phase 1 43 participants

GCC Agonist Signal in the Small Intestine

University of Wisconsin, Madison

NCT05107219

COMPLETED Phase 1 14 participants

Alisertib and Combination Chemotherapy in Treating Patients With Gastrointestinal Tumors

National Cancer Institute (NCI)

NCT02319018

COMPLETED NA 8 participants

Narrative Medicine for Improving Well-Being in Patients With Gastrointestinal Cancers

University of Southern California

NCT06374251

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 3

Named interventions

Most-linked intervention names on Malignant Digestive System Neoplasm records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Questionnaire Administration Other
6 trials
Quality-of-Life Assessment Other
5 trials
Biospecimen Collection Procedure
3 trials
Oxaliplatin Drug
2 trials
Fluorouracil Drug
2 trials
Plecanatide Drug
1 trials
Linaclotide Drug
1 trials
Thermal Ablation Therapy Procedure
1 trials

US sites by state

Facility locations filed on Malignant Digestive System Neoplasm trials. A trial with sites in several states counts in each.

Texas 5 trials
Michigan 2 trials
Maryland 2 trials
Georgia 2 trials
California 2 trials
Arizona 2 trials
Wisconsin 1 trials
Tennessee 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Malignant Digestive System Neoplasm page

12 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 6 Malignant Digestive System Neoplasm trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • M.D. Anderson Cancer Center sponsors the most Malignant Digestive System Neoplasm trials on record, review their full trial history before evaluating a specific study. See M.D. Anderson Cancer Center's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Malignant Digestive System Neoplasm condition card totals 12 registered trials; most-linked intervention Questionnaire Administration; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.