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ClinicalTrials.gov enrollment closed early-phase tilt small index

Locally Advanced Malignant Neoplasm: early-phase trial registry

A small indexed set (12 trials) with no open enrollment listed right now.

Corpus placement: #1,429 of 28,707 conditions by registered trial count.

12 US clinical trials · none currently recruiting · #1,429 of 28,707 conditions by registered trial count

Locally Advanced Malignant Neoplasm: 12 US clinical trials tracked, none currently recruiting.

Locally Advanced Malignant Neoplasm is the subject of 12 registered US clinical trials on ClinicalTrials.gov, none currently recruiting. 1 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 7 of these trials.

Enrollment posture brief

Registry condition locally-advanced-malignant-neoplasm

OPEN 0 | RECR 0% | LATE 1 | EARLY 6 | RANK #1429 | SPON 7

Nearest open-share peer: Adenocarcinoma of the Gastroesophageal Junction (0% recruiting · 8 trials)

Acute Myeloid Leukemia in Re41.7%Adenocarcinoma of the Rectum41.7%Adherence, Patient16.7%Accelerated Phase Chronic My0%Locally Advanced Maligna (th…0%
Open-enrollment share among volume-matched conditions near Locally Advanced Malignant Neoplasm

Locally Advanced Malignant Neoplasm has no open enrollment in this registry pull (12 archived studies). Peers show how other volume-matched labels compare on open share. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Locally Advanced Malignant Neoplasm on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Locally Advanced Malignant Neoplasm is recruiting below its size-band peers.

    0 of 12 indexed trials (0%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Locally Advanced Malignant Neoplasm research.

    M.D. Anderson Cancer Center accounts for 7 of 12 trials (58.3%). 6 distinct sponsors appear on at least one study for this condition label.

  3. Typical Locally Advanced Malignant Neoplasm enrolment sits around 70 participants.

    Median target enrolment is 70 among the 12 trials that report a genuine target (sentinel values excluded). 7 of those (58.3%) plan for fewer than 100 participants.

  4. Locally Advanced Malignant Neoplasm research is mostly interventional.

    10 interventional and 2 observational studies make up this index (83.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 23Phase 31

Indexed trials (enrollment closed)

12 total, page 1 of 1

ACTIVE NOT RECRUITING NA 406 participants

Preference of Room Setting and Waiting Time in Patients With Advanced, Locally Advanced, or Metastatic Cancer and Their Caregivers Who Are Seen in the Outpatient Supportive/Palliative Care Center

M.D. Anderson Cancer Center

NCT03671226

ACTIVE NOT RECRUITING 141 participants

Financial Distress in Advanced Cancer Patients

M.D. Anderson Cancer Center

NCT04053517

ACTIVE NOT RECRUITING Phase 2 110 participants

Haloperidol and Lorazepam in Controlling Symptoms of Persistent Agitated Delirium in Patients With Advanced Cancer Undergoing Palliative Care

M.D. Anderson Cancer Center

NCT03743649

ACTIVE NOT RECRUITING Phase 2 70 participants

Haloperidol With or Without Chlorpromazine in Treating Delirium in Patients With Advanced, Metastatic, or Recurrent Cancer

M.D. Anderson Cancer Center

NCT03021486

ACTIVE NOT RECRUITING NA 40 participants

Microbiome and Rectal Cancer

University of South Florida

NCT04223102

COMPLETED 351 participants

Caregiver Burden, Quality of Life, and Symptom Distress at Different Palliative Cancer Care Settings

M.D. Anderson Cancer Center

NCT04186884

COMPLETED NA 125 participants

Videos and Questionnaires in Assessing Patient Perception of Physician's Compassion, Communication Skills, and Professionalism During Clinic Visits

M.D. Anderson Cancer Center

NCT03856060

COMPLETED Phase 1 45 participants

A Phase 1 Study to Investigate Axatilimab Alone or in Combination With Durvalumab in Patients With Solid Tumors

Syndax Pharmaceuticals

NCT03238027

COMPLETED Phase 1 30 participants

A Study of ALT-836 in Combination With Gemcitabine for Locally Advanced or Metastatic Solid Tumors

Altor BioScience

NCT01325558

COMPLETED Phase 3 28 participants

Extraperitoneal Para-aortic Lymph Node Dissection (EPLND) for Cervix

M.D. Anderson Cancer Center

NCT01365156

COMPLETED Phase 1 10 participants

Chemoimmunotherapy and Radiation in Pancreatic Cancer

Providence Health & Services

NCT01903083

COMPLETED Phase 2 10 participants

Study of Propranolol in Newly Diagnosed Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy

Columbia University

NCT01847001

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 3
Phase 3 1

Named interventions

Most-linked intervention names on Locally Advanced Malignant Neoplasm records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Questionnaire Administration Other
6 trials
Quality-of-Life Assessment Other
4 trials
Haloperidol Drug
2 trials
DOT imaging Other
1 trials
ALT-836 in combination with gemcitabine Biological
1 trials
Pancreaticoduodenectomy Procedure
1 trials
Extraperitoneal laparoscopic lymphadenectomy (EPLND) Procedure
1 trials
Tissue collection Procedure
1 trials

US sites by state

Facility locations filed on Locally Advanced Malignant Neoplasm trials. A trial with sites in several states counts in each.

Texas 8 trials
Oregon 2 trials
New York 2 trials
Virginia 1 trials
North Carolina 1 trials
Maryland 1 trials
Iowa 1 trials
Georgia 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Locally Advanced Malignant Neoplasm page

12 registered trials, 0 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • No Locally Advanced Malignant Neoplasm trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
  • M.D. Anderson Cancer Center sponsors the most Locally Advanced Malignant Neoplasm trials on record, review their full trial history before evaluating a specific study. See M.D. Anderson Cancer Center's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Locally Advanced Malignant Neoplasm condition card totals 12 registered trials; most-linked intervention Questionnaire Administration; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.