Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Krabbe Disease: early-phase trial registry
2 of 5 indexed Krabbe Disease trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #3,391 of 28,707 conditions by registered trial count.
5 US clinical trials · 2 currently recruiting · #3,391 of 28,707 conditions by registered trial count
Krabbe Disease: 5 US clinical trials tracked, 2 recruiting.
Krabbe Disease is the subject of 5 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Forge Biologics, running 2 of these trials.
Enrollment posture brief
Registry condition krabbe-disease
OPEN 2 | RECR 40% | LATE 0 | EARLY 2 | RANK #3391 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Achondroplasia (40% recruiting · 10 trials)
Krabbe Disease lists 2 open slots (40% of 5 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Krabbe Disease on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Krabbe Disease is recruiting below its size-band peers.
2 of 5 indexed trials (40%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Krabbe Disease research.
Forge Biologics accounts for 2 of 5 trials (40%). 3 distinct sponsors appear on at least one study for this condition label.
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Most Krabbe Disease trials plan to enrol fewer than 100 people.
Median target enrolment is 60 among the 5 trials that report a genuine target (sentinel values excluded). 3 of those (60%) plan for fewer than 100 participants.
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Krabbe Disease research leans observational.
2 interventional and 3 observational studies make up this index (40% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
5 total, page 1 of 1
Longitudinal Study of Neurodegenerative Disorders
University of Pittsburgh
NCT03333200
Krabbe Disease Global Patient Registry
State University of New York at Buffalo
NCT02993796
Diffusion Tensor Imaging (DTI) in Infants With Krabbe Disease
University of Pittsburgh
NCT00787865
Gene Transfer Clinical Trial for Infantile and Late Infantile Krabbe Disease Treated Previously With HSCT
Forge Biologics
NCT05739643
Gene Transfer Clinical Trial for Krabbe Disease
Forge Biologics
NCT04693598
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Krabbe Disease records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Krabbe Disease trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Krabbe Disease page
5 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 2 Krabbe Disease trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Forge Biologics sponsors the most Krabbe Disease trials on record, review their full trial history before evaluating a specific study. See Forge Biologics's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Krabbe Disease condition card totals 5 registered trials; most-linked intervention FBX-101; top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.