Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Knee Arthroplasty: early-phase trial registry
2 of 6 indexed Knee Arthroplasty trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #2,866 of 28,707 conditions by registered trial count.
6 US clinical trials · 2 currently recruiting · #2,866 of 28,707 conditions by registered trial count
Knee Arthroplasty: 6 US clinical trials tracked, 2 recruiting.
Knee Arthroplasty is the subject of 6 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Yale University, running 2 of these trials.
Enrollment posture brief
Registry condition knee-arthroplasty
OPEN 2 | RECR 33% | LATE 0 | EARLY 2 | RANK #2866 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Adherence, Treatment (33% recruiting · 6 trials)
Knee Arthroplasty lists 2 open slots (33% of 6 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Knee Arthroplasty on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Knee Arthroplasty is recruiting below its size-band peers.
2 of 6 indexed trials (33.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Knee Arthroplasty research.
Yale University accounts for 2 of 6 trials (33.3%). 5 distinct sponsors appear on at least one study for this condition label.
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Typical Knee Arthroplasty enrolment sits around 176 participants.
Median target enrolment is 176 among the 6 trials that report a genuine target (sentinel values excluded). 2 of those (33.3%) plan for fewer than 100 participants.
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Knee Arthroplasty research is mostly interventional.
5 interventional and 1 observational studies make up this index (83.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
6 total, page 1 of 1
Yale Steroid Enhanced Versus Exparel Nerveblock TKA RCT Study
Yale University
NCT05279092
Yale Steroid Enhanced Versus Exparel Nerveblock TKA Part 2
Yale University
NCT05736549
Hospital for Special Surgery Knee Arthroplasty Cohort
Hospital for Special Surgery, New York
NCT00454467
Patient Understanding and Satisfaction in Informed Consent for Total Knee Arthroplasty
jasvinder singh
NCT01582984
Three Different Approaches for Ultrasound Guided Femoral Nerve Block for Patients Undergoing Total Knee Arthroplasty
Chicago Anesthesia Pain Specialists
NCT01763814
Technology Interventions to Improve Outcomes After Knee Replacement
University of South Carolina
NCT04482400
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Knee Arthroplasty records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Knee Arthroplasty trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Knee Arthroplasty page
6 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 2 Knee Arthroplasty trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Yale University sponsors the most Knee Arthroplasty trials on record, review their full trial history before evaluating a specific study. See Yale University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Knee Arthroplasty condition card totals 6 registered trials; most-linked intervention Bupivacaine -Dexamethasone Sodium Phosphate-Methylprednisolone Acetate; top US site state Connecticut. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.