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Glioblastoma (GBM): early-phase trial registry
7 of 8 indexed Glioblastoma (GBM) trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #2,176 of 28,707 conditions by registered trial count.
8 US clinical trials · 7 currently recruiting · #2,176 of 28,707 conditions by registered trial count
Glioblastoma (GBM): 8 US clinical trials tracked, 7 recruiting.
Glioblastoma (GBM) is the subject of 8 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is James Markert, MD, running 1 of these trials.
Enrollment posture brief
Registry condition glioblastoma-gbm
OPEN 7 | RECR 88% | LATE 0 | EARLY 7 | RANK #2176 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Aortic Diseases (88% recruiting · 8 trials)
Glioblastoma (GBM) lists 7 open slots (88% of 8 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Glioblastoma (GBM) on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Glioblastoma (GBM) is recruiting above its size-band peers.
7 of 8 indexed trials (87.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Glioblastoma (GBM) trials is spread across many organizations.
James Markert, MD accounts for 1 of 8 trials (12.5%). 8 distinct sponsors appear on at least one study for this condition label.
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Most Glioblastoma (GBM) trials plan to enrol fewer than 100 people.
Median target enrolment is 60 among the 8 trials that report a genuine target (sentinel values excluded). 5 of those (62.5%) plan for fewer than 100 participants.
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Glioblastoma (GBM) research is mostly interventional.
8 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
8 total, page 1 of 1
DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM)
Diakonos Oncology Corporation
NCT06805305
Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII
Black Diamond Therapeutics
NCT07326566
FearLess in NeuroOncology
Virginia Commonwealth University
NCT06989086
G-CSF After Chemo-radiation in Patients With Glioblastoma
Massachusetts General Hospital
NCT06649851
Enhanced Local Intensified Radiation Therapy in Elderly Glioblastoma: A Phase 2 Hybrid Randomized Trial
Brigham and Women's Hospital
NCT06835803
A Phase 0/1 Clinical Trial With an Expansion Phase of GSK5764227, a B7-H3-Targeted Antibody-Drug Conjugate (ADC), in Patients With Recurrent Grade 4 Glioma and Patients With Brain Metastases
Nader Sanai
NCT07268053
Study of Low-Intensity Focused Ultrasound in Combination With Immunotherapy in Newly Diagnosed Unmethylated Glioblastoma
University of Virginia
NCT07343986
A Phase IB 2 Dose Trial of IRS-1 HSV C134 (IND 17296) Administered Intratumorally in Patients With Recurrent Malignant Glioma
James Markert, MD
NCT06614855
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 4 |
Top Sponsors
Named interventions
Most-linked intervention names on Glioblastoma (GBM) records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Glioblastoma (GBM) trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Glioblastoma (GBM) page
8 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 7 Glioblastoma (GBM) trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- James Markert, MD sponsors the most Glioblastoma (GBM) trials on record, review their full trial history before evaluating a specific study. See James Markert, MD's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Glioblastoma (GBM) condition card totals 8 registered trials; most-linked intervention C134; top US site state Virginia. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.