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ClinicalTrials.gov 4 recruiting now early-phase tilt small index

Endometrial Clear Cell Adenocarcinoma: early-phase trial registry

4 of 11 indexed Endometrial Clear Cell Adenocarcinoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,577 of 28,707 conditions by registered trial count.

11 US clinical trials · 4 currently recruiting · #1,577 of 28,707 conditions by registered trial count

Endometrial Clear Cell Adenocarcinoma: 11 US clinical trials tracked, 4 recruiting.

Endometrial Clear Cell Adenocarcinoma is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 7 of these trials.

Enrollment posture brief

Registry condition endometrial-clear-cell-adenocarcinoma

OPEN 4 | RECR 36% | LATE 3 | EARLY 6 | RANK #1577 | SPON 7

Nearest open-share peer: Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive (36% recruiting · 11 trials)

Acute Pancreatitis81.8%Acute Stroke45.5%Acquired Brain Injury36.4%Endometrial Clear Cell A (th…36%Acute Lung Injury9.1%
Open-enrollment share among volume-matched conditions near Endometrial Clear Cell Adenocarcinoma

Endometrial Clear Cell Adenocarcinoma lists 4 open slots (36% of 11 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Endometrial Clear Cell Adenocarcinoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Endometrial Clear Cell Adenocarcinoma is recruiting below its size-band peers.

    4 of 11 indexed trials (36.4%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Endometrial Clear Cell Adenocarcinoma research.

    National Cancer Institute (NCI) accounts for 7 of 11 trials (63.6%). 4 distinct sponsors appear on at least one study for this condition label.

  3. Typical Endometrial Clear Cell Adenocarcinoma enrolment sits around 101 participants.

    Median target enrolment is 101 among the 11 trials that report a genuine target (sentinel values excluded). 5 of those (45.5%) plan for fewer than 100 participants.

  4. Endometrial Clear Cell Adenocarcinoma research is mostly interventional.

    10 interventional and 1 observational studies make up this index (90.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 24Phase 33

Open and recent trials

11 total, page 1 of 1

RECRUITING 1,000 participants

Determine the Utility of Liquid Biopsies and Tumor Molecular Profiling in Predicting Recurrence in Endometrial Cancers

M.D. Anderson Cancer Center

NCT05049538

RECRUITING Phase 3 360 participants

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

National Cancer Institute (NCI)

NCT05256225

RECRUITING Phase 3 188 participants

Short Course Vaginal Cuff Brachytherapy in Treating Participants With Stage I-II Endometrial Cancer

University of Utah

NCT03422198

RECRUITING Phase 2 81 participants

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

National Cancer Institute (NCI)

NCT05112601

ACTIVE NOT RECRUITING Phase 3 813 participants

Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) in Stage III-IV or Recurrent Endometrial Cancer

National Cancer Institute (NCI)

NCT03914612

ACTIVE NOT RECRUITING Phase 2 349 participants

Paclitaxel, Carboplatin, and Bevacizumab or Paclitaxel, Carboplatin, and Temsirolimus or Ixabepilone, Carboplatin, and Bevacizumab in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial Cancer

National Cancer Institute (NCI)

NCT00977574

ACTIVE NOT RECRUITING NA 101 participants

PET/CT and Lymph Node Mapping in Finding Lymph Node Metastasis in Patients With High-Risk Endometrial Cancer

M.D. Anderson Cancer Center

NCT01737619

ACTIVE NOT RECRUITING Phase 1 50 participants

TORC1/2 Inhibitor MLN0128 and Bevacizumab in Treating Patients With Recurrent Glioblastoma or Advanced Solid Tumors

National Cancer Institute (NCI)

NCT02142803

COMPLETED Phase 2 37 participants

Akt Inhibitor MK2206 in Treating Patients With Recurrent or Advanced Endometrial Cancer

National Cancer Institute (NCI)

NCT01307631

COMPLETED Phase 2 37 participants

Nintedanib in Treating Patients With Recurrent or Persistent Endometrial Cancer

Gynecologic Oncology Group

NCT01225887

COMPLETED Phase 1 26 participants

Trametinib With or Without GSK2141795 in Treating Patients With Recurrent or Persistent Endometrial Cancer

National Cancer Institute (NCI)

NCT01935973

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 4
Phase 3 3

Named interventions

Most-linked intervention names on Endometrial Clear Cell Adenocarcinoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Laboratory Biomarker Analysis Other
5 trials
Computed Tomography Procedure
4 trials
Biospecimen Collection Procedure
3 trials
Carboplatin Drug
3 trials
Bevacizumab Biological
2 trials
Paclitaxel Drug
2 trials
Uprosertib Drug
1 trials
Lymph Node Mapping Procedure
1 trials

US sites by state

Facility locations filed on Endometrial Clear Cell Adenocarcinoma trials. A trial with sites in several states counts in each.

Texas 5 trials
California 5 trials
Illinois 4 trials
Georgia 3 trials
Connecticut 3 trials
Arizona 3 trials
Alabama 3 trials
Ohio 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Endometrial Clear Cell Adenocarcinoma page

11 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Endometrial Clear Cell Adenocarcinoma condition card totals 11 registered trials; most-linked intervention Laboratory Biomarker Analysis; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.