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ClinicalTrials.gov 5 recruiting now official registry

COVID clinical trials

5 of 15 indexed COVID trials are currently recruiting.

15 US clinical trials · 5 currently recruiting

COVID is the subject of 15 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is University of Minnesota, running 3 of these trials.

The research picture

COVID has 15 registered US clinical trials, 5 of them open to new participants right now, about 33% of the total.

5
recruiting participants now
33%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
3
top sponsor: University of Minnesota
Phase 11Phase 21Phase 32

Active & Recent Trials

15 total, page 1 of 1

RECRUITING 1,500 participants

Prospective Clinical Evaluation of the BioFire Emerging Coronavirus Panel for the Detection of COVID-19 and Other Coronaviruses

BioFire Defense

NCT07221097

RECRUITING NA 1,000 participants

Clinical Validation of the Aptitude Medical Systems Metrix COVID-19 Test

Aptitude Medical Systems

NCT06744660

RECRUITING Phase 3 820 participants

Outpatient Treatment With Anti-Coronavirus Immunoglobulin

University of Minnesota

NCT04910269

RECRUITING 800 participants

Long-term Impact of Infection With Novel Coronavirus (COVID-19)

University of California, San Francisco

NCT04362150

RECRUITING 250 participants

A Study to Explore the Role of Gut Flora in COVID-19 Infection

ProgenaBiome

NCT04359836

ACTIVE NOT RECRUITING 7,965 participants

Assessing the Safety of Pregnancy In the CoRonavirus (COVID-19) pandEmic

University of California, San Francisco

NCT04388605

ACTIVE NOT RECRUITING 201 participants

COVID-19 Biorepository

University of Kansas Medical Center

NCT04568148

COMPLETED 22,213 participants

ACEI or ARB and COVID-19 Severity and Mortality in US Veterans

University of Utah

NCT04467931

COMPLETED Phase 3 593 participants

Inpatient Treatment of COVID-19 With Anti-Coronavirus Immunoglobulin (ITAC)

University of Minnesota

NCT04546581

COMPLETED 461 participants

Evaluation of Antibody Tests for COVID-19

Washington University School of Medicine

NCT04360954

COMPLETED 250 participants

Early Short Course Corticosteroids in COVID-19

Henry Ford Health System

NCT04374071

COMPLETED NA 143 participants

HSS Covid-19 Antibody Serology Among Surgeons & Anesthesiologists

Hospital for Special Surgery, New York

NCT04389294

COMPLETED 129 participants

Assessment of Exam Findings in Coronavirus Disease 2019 (COVID-19) With Point-of-Care Ultrasonography (POCUS)

University of Minnesota

NCT04339998

COMPLETED Phase 1 72 participants

A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19

Apellis Pharmaceuticals

NCT04402060

COMPLETED Phase 2 48 participants

Convalescent Plasma in the Treatment of COVID 19

Trinity Health Of New England

NCT04343261

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 1
Phase 3 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the COVID Trial Landscape

15 indexed COVID studies · 5 recruiting (33%).

Phase mix: 2 late (III/IV) vs 2 early (I/II).

Top sponsor: University of Minnesota (3 trials), 9 others listed. 15 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for COVID?

PlainTrial tracks 15 US clinical trials for COVID, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for COVID?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.