Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Congenital Abnormalities: later-stage trial registry
2 of 6 indexed Congenital Abnormalities trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #2,866 of 28,707 conditions by registered trial count.
6 US clinical trials · 2 currently recruiting · #2,866 of 28,707 conditions by registered trial count
Congenital Abnormalities: 6 US clinical trials tracked, 2 recruiting.
Congenital Abnormalities is the subject of 6 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is Kastle Therapeutics, running 1 of these trials.
Enrollment posture brief
Registry condition congenital-abnormalities
OPEN 2 | RECR 33% | LATE 1 | EARLY 0 | RANK #2866 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Adherence, Treatment (33% recruiting · 6 trials)
Congenital Abnormalities lists 2 open slots (33% of 6 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Congenital Abnormalities on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Congenital Abnormalities is recruiting below its size-band peers.
2 of 6 indexed trials (33.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Congenital Abnormalities research.
Kastle Therapeutics accounts for 1 of 6 trials (16.7%). 6 distinct sponsors appear on at least one study for this condition label.
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Typical Congenital Abnormalities enrolment sits around 250 participants.
Median target enrolment is 250 among the 6 trials that report a genuine target (sentinel values excluded). 1 of those (16.7%) plan for fewer than 100 participants.
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Congenital Abnormalities research is mostly interventional.
5 interventional and 1 observational studies make up this index (83.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
6 total, page 1 of 1
Pregnancies Complicated by Fetal Anomalies
University of Tennessee
NCT02505464
Prospective Registry for Long-term Outcomes Following FETO in Severe Left and Right CDH
Johns Hopkins University
NCT07166172
Safety and Efficacy Study of reSept ASD Occluder for Treating Secundum ASD
atHeart Medical
NCT04591392
Medtronic Hugo™ Robotic Assisted Surgery (RAS) System in Urologic Surgery (Expand URO)
Medtronic - MITG
NCT05696444
NCGENES: North Carolina Clinical Genomic Evaluation by NextGen Exome Sequencing
University of North Carolina, Chapel Hill
NCT01969370
An Open-label Extension Study to Assess the Long-term Safety and Efficacy of ISIS 301012 (Mipomersen) in Patients With Familial Hypercholesterolemia or Severe-Hypercholesterolemia
Kastle Therapeutics
NCT00694109
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 3 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Congenital Abnormalities records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Congenital Abnormalities trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Congenital Abnormalities page
6 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 2 Congenital Abnormalities trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Kastle Therapeutics sponsors the most Congenital Abnormalities trials on record, review their full trial history before evaluating a specific study. See Kastle Therapeutics's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Congenital Abnormalities condition card totals 6 registered trials; most-linked intervention Mipomersen Sodium; top US site state Ohio. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.