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ClinicalTrials.gov 9 recruiting now later-stage tilt small index

Breast Reconstruction: later-stage trial registry

9 of 19 indexed Breast Reconstruction trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #902 of 28,707 conditions by registered trial count.

19 US clinical trials · 9 currently recruiting · #902 of 28,707 conditions by registered trial count

Breast Reconstruction: 19 US clinical trials tracked, 9 recruiting.

Breast Reconstruction is the subject of 19 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Mentor Worldwide, running 2 of these trials.

Enrollment posture brief

Registry condition breast-reconstruction

OPEN 9 | RECR 47% | LATE 5 | EARLY 2 | RANK #902 | SPON 2

Nearest open-share peer: Breast Cancer Stage I (47% recruiting · 19 trials)

Amyotrophic Lateral Sclerosi52.6%Breast Reconstruction (this)47%Anesthesia, Local42.1%Alcohol Consumption36.8%Attention Deficit Hyperactiv26.3%
Open-enrollment share among volume-matched conditions near Breast Reconstruction

Breast Reconstruction lists 9 open slots (47% of 19 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Breast Reconstruction on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Breast Reconstruction recruits in line with its size-band peers.

    9 of 19 indexed trials (47.4%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Breast Reconstruction trials is spread across many organizations.

    Mentor Worldwide accounts for 2 of 19 trials (10.5%). 18 distinct sponsors appear on at least one study for this condition label.

  3. Typical Breast Reconstruction enrolment sits around 184 participants.

    Median target enrolment is 184 among the 19 trials that report a genuine target (sentinel values excluded). 7 of those (36.8%) plan for fewer than 100 participants.

  4. Breast Reconstruction research is mostly interventional.

    19 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 21Phase 33Phase 42

Open and recent trials

19 total, page 1 of 1

RECRUITING Phase 3 783 participants

Evaluation of the Safety and Effectiveness of ARTIA Reconstructive Tissue Matrix Breast Reconstruction (ADORA) in Adult Participants

AbbVie

NCT06575192

RECRUITING NA 702 participants

Melodi Matrix™ in Breast Reconstruction

Melodi Health

NCT06027996

RECRUITING NA 500 participants

A Study on Pain After Breast Reconstruction

Memorial Sloan Kettering Cancer Center

NCT06627582

RECRUITING NA 467 participants

Acellular Dermal Matrix Investigation in Breast Reconstruction

RTI Surgical

NCT06456554

RECRUITING NA 300 participants

Breast Mesh Used in Two-staged Breast Reconstruction

Tianjin Medical University Cancer Institute and Hospital

NCT04967976

RECRUITING NA 212 participants

Impact of Pectoral Versus Paravertebral Blocks on Pain and Physical Well-Being in Implant-Based Breast Reconstruction

Amy Colwell

NCT07209436

RECRUITING NA 135 participants

A Comparative Analysis of REVOLVE, LipoGrafter, and Viality in Autologous Fat Grafting During Breast Surgery

Weill Medical College of Cornell University

NCT04891510

RECRUITING NA 68 participants

SAVE Trial: SAfe Opioid Use Video Education

University of Utah

NCT07044583

RECRUITING NA 62 participants

Pulsed Lavage in Implant-Based Breast Reconstruction

University of Alabama at Birmingham

NCT05585710

ACTIVE NOT RECRUITING NA 382 participants

Pre- Versus Sub-pectoral Implant-based Breast Reconstruction After Skin-sparing Mastectomy or Nipple-sparing Mastectomy OPBC-02PREPEC

University Hospital, Basel, Switzerland

NCT04293146

ACTIVE NOT RECRUITING NA 30 participants

Abdominal Scar Improvement in Microsurgical Breast Reconstruction

Stanford University

NCT05377723

COMPLETED Phase 3 1,891 participants

CPG Styles Study: A Study of the Safety of the Contour Profile Gel Breast Implants (CPG Styles Study)

Mentor Worldwide

NCT01959880

COMPLETED Phase 3 955 participants

Mentor Siltex® Contour Profile Gel Mammary Prosthesis Clinical Trial

Mentor Worldwide

NCT00812097

COMPLETED Phase 2 184 participants

A Study of Granexin® Gel for the Reduction of Scar Formation in Surgical Wounds Following Bilateral Anchor Incision Breast Surgery

Xequel Bio

NCT04331080

COMPLETED Phase 1 183 participants

Toradol (Ketorolac) in Breast Surgery to Reduce Pain & Opioid Use

Carilion Clinic

NCT04439396

COMPLETED NA 75 participants

Nipple Sparing Mastectomy - Cosmetic Outcomes

Wake Forest University Health Sciences

NCT01002014

COMPLETED Phase 4 60 participants

Comparing Local Anesthetics for TAP Block During Abdominally-based Free Flap for Breast Reconstruction

Vanderbilt University Medical Center

NCT03700970

COMPLETED NA 52 participants

Pilot Study Assessing Breast Temperature in Breast Cancer Patients

Duke University

NCT03376035

COMPLETED Phase 4 48 participants

A Comparison of Dermal Autograft to AlloDerm in Breast Reconstruction

University of Kentucky

NCT01561287

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 1
Phase 3 3
Phase 4 2

Named interventions

Most-linked intervention names on Breast Reconstruction records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Mentor Siltex® Contour Profile Gel Mammary Prosthesis Device
1 trials
AlloDerm Procedure
1 trials
Dermal Autograft Procedure
1 trials
Temperature measurement of breast Other
1 trials
Nipple Sparing Mastectomy Procedure
1 trials
Regular bupivacaine Drug
1 trials
The Contour Profile Gel (CPG) breast implants Device
1 trials
Granexin® gel 200 μM Drug
1 trials

US sites by state

Facility locations filed on Breast Reconstruction trials. A trial with sites in several states counts in each.

California 7 trials
New York 6 trials
Texas 4 trials
North Carolina 4 trials
Utah 3 trials
Ohio 3 trials
Virginia 2 trials
Tennessee 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Breast Reconstruction page

19 registered trials, 9 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 9 Breast Reconstruction trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Mentor Worldwide sponsors the most Breast Reconstruction trials on record, review their full trial history before evaluating a specific study. See Mentor Worldwide's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Breast Reconstruction condition card totals 19 registered trials; most-linked intervention Mentor Siltex® Contour Profile Gel Mammary Prosthesis; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.