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ClinicalTrials.gov 9 recruiting now official registry

Breast Reconstruction clinical trials

9 of 19 indexed Breast Reconstruction trials are currently recruiting.

19 US clinical trials · 9 currently recruiting

Breast Reconstruction is the subject of 19 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Mentor Worldwide, running 2 of these trials.

The research picture

Breast Reconstruction has 19 registered US clinical trials, 9 of them open to new participants right now, about 47% of the total.

9
recruiting participants now
47%
of trials open to enrollment
5
in Phase 3–4 (later-stage)
2
top sponsor: Mentor Worldwide
Phase 11Phase 21Phase 33Phase 42

Active & Recent Trials

19 total, page 1 of 1

RECRUITING Phase 3 783 participants

Evaluation of the Safety and Effectiveness of ARTIA Reconstructive Tissue Matrix Breast Reconstruction (ADORA) in Adult Participants

AbbVie

NCT06575192

RECRUITING NA 702 participants

Melodi Matrix™ in Breast Reconstruction

Melodi Health

NCT06027996

RECRUITING NA 500 participants

A Study on Pain After Breast Reconstruction

Memorial Sloan Kettering Cancer Center

NCT06627582

RECRUITING NA 467 participants

Acellular Dermal Matrix Investigation in Breast Reconstruction

RTI Surgical

NCT06456554

RECRUITING NA 300 participants

Breast Mesh Used in Two-staged Breast Reconstruction

Tianjin Medical University Cancer Institute and Hospital

NCT04967976

RECRUITING NA 212 participants

Impact of Pectoral Versus Paravertebral Blocks on Pain and Physical Well-Being in Implant-Based Breast Reconstruction

Amy Colwell

NCT07209436

RECRUITING NA 135 participants

A Comparative Analysis of REVOLVE, LipoGrafter, and Viality in Autologous Fat Grafting During Breast Surgery

Weill Medical College of Cornell University

NCT04891510

RECRUITING NA 68 participants

SAVE Trial: SAfe Opioid Use Video Education

University of Utah

NCT07044583

RECRUITING NA 62 participants

Pulsed Lavage in Implant-Based Breast Reconstruction

University of Alabama at Birmingham

NCT05585710

ACTIVE NOT RECRUITING NA 382 participants

Pre- Versus Sub-pectoral Implant-based Breast Reconstruction After Skin-sparing Mastectomy or Nipple-sparing Mastectomy OPBC-02PREPEC

University Hospital, Basel, Switzerland

NCT04293146

ACTIVE NOT RECRUITING NA 30 participants

Abdominal Scar Improvement in Microsurgical Breast Reconstruction

Stanford University

NCT05377723

COMPLETED Phase 3 1,891 participants

CPG Styles Study: A Study of the Safety of the Contour Profile Gel Breast Implants (CPG Styles Study)

Mentor Worldwide

NCT01959880

COMPLETED Phase 3 955 participants

Mentor Siltex® Contour Profile Gel Mammary Prosthesis Clinical Trial

Mentor Worldwide

NCT00812097

COMPLETED Phase 2 184 participants

A Study of Granexin® Gel for the Reduction of Scar Formation in Surgical Wounds Following Bilateral Anchor Incision Breast Surgery

Xequel Bio

NCT04331080

COMPLETED Phase 1 183 participants

Toradol (Ketorolac) in Breast Surgery to Reduce Pain & Opioid Use

Carilion Clinic

NCT04439396

COMPLETED NA 75 participants

Nipple Sparing Mastectomy - Cosmetic Outcomes

Wake Forest University Health Sciences

NCT01002014

COMPLETED Phase 4 60 participants

Comparing Local Anesthetics for TAP Block During Abdominally-based Free Flap for Breast Reconstruction

Vanderbilt University Medical Center

NCT03700970

COMPLETED NA 52 participants

Pilot Study Assessing Breast Temperature in Breast Cancer Patients

Duke University

NCT03376035

COMPLETED Phase 4 48 participants

A Comparison of Dermal Autograft to AlloDerm in Breast Reconstruction

University of Kentucky

NCT01561287

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 1
Phase 3 3
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Breast Reconstruction Trial Landscape

19 indexed Breast Reconstruction studies · 9 recruiting (47%).

Phase mix: 5 late (III/IV) vs 2 early (I/II).

Top sponsor: Mentor Worldwide (2 trials), 9 others listed. 19 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Breast Reconstruction?

PlainTrial tracks 19 US clinical trials for Breast Reconstruction, of which 9 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Breast Reconstruction?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.