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NCT04439396 · ClinicalTrials.gov registry record · Phase 1
Toradol (Ketorolac) in Breast Surgery to Reduce Pain & Opioid Use
A Phase 1 study of Breast Reconstruction and Breast Reduction, sponsored by Carilion Clinic.
- Completed
- Registry status
- Phase 1
- Development phase
- 183
- Enrollment target
- 1
- Study location
NCT04439396: Completed Phase 1 study of Breast Reconstruction and Breast Reduction, sponsored by Carilion Clinic.
NCT04439396 is a Phase 1 study of Breast Reconstruction and Breast Reduction that has completed, run by Carilion Clinic. The registered enrollment target is 183 participants, below the 384-participant average among 18 other Breast Reconstruction trials with a reported enrollment target (52% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04439396, a Phase 1 study of Breast Reconstruction and Breast Reduction, has completed, sponsored by Carilion Clinic.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 183 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to investigate whether perioperative single-dose administration of ketorolac (Toradol) can reduce post-operative pain after breast surgery, thereby decreasing post-operative opioid use.
Primary Outcome
This will be assessed by using a Likert scale(0=no pain to 10=extreme pain) for pain in the post-operative period before they are discharged. If patients are kept overnight then another pain assessment will be done. Additionally, patients will keep a 2-week diary of average pain in the morning and evening each day until their 2 week follow up visit.
Conditions Studied
Interventions
- OTHER Saline
- DRUG Ketorolac Tromethamine
Study Locations (1)
Virginia
- James T. Thompson - Roanoke
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 183 participants |
| Start Date | 2020-06-22 |
| Est. Completion | 2023-01-30 |
| Phase | Phase 1 |
What the finished NCT04439396 record still lists
NCT04439396 is an interventional study that assigns participants to a tested intervention. The registered 183 participants enrollment target is mid-sized for trials with a published cap, below the 384-participant average among 18 other Breast Reconstruction trials with a reported enrollment target (52% lower).
The record links to 2 conditions, with Breast Reconstruction appearing as the primary indexed condition, and to 2 interventions - of which Saline is the first listed.
NCT04439396 reports a single indexed study location in Virginia.
Frequently Asked Questions
What is clinical trial NCT04439396 about?
NCT04439396 is a clinical study titled "Toradol (Ketorolac) in Breast Surgery to Reduce Pain & Opioid Use". The purpose of this study is to investigate whether perioperative single-dose administration of ketorolac (Toradol) can reduce post-operative pain after breast surgery, thereby decreasing post-operative opioid use.
What is the current status of trial NCT04439396?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 183 participants. The study started on 2020-06-22. Estimated completion is 2023-01-30.
What conditions does trial NCT04439396 study?
This clinical trial studies the following conditions: Breast Reconstruction, Breast Reduction.
What interventions are being tested in trial NCT04439396?
The interventions under investigation include: Saline (OTHER), Ketorolac Tromethamine (DRUG).
Who is sponsoring clinical trial NCT04439396?
This trial is sponsored by Carilion Clinic, which has 45 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04439396 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Breast Reconstruction
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04439396's enrollment target sits among peer trials
183 11th of 18 higher than 8 of 18 other Breast Reconstruction trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Reconstruction trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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