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ClinicalTrials.gov 6 recruiting now early-phase tilt small index

B-ALL: early-phase trial registry

6 of 8 indexed B-ALL trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #2,176 of 28,707 conditions by registered trial count.

8 US clinical trials · 6 currently recruiting · #2,176 of 28,707 conditions by registered trial count

B-ALL: 8 US clinical trials tracked, 6 recruiting.

B-ALL is the subject of 8 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 3 of these trials.

Enrollment posture brief

Registry condition b-all

OPEN 6 | RECR 75% | LATE 0 | EARLY 5 | RANK #2176 | SPON 3

Nearest open-share peer: Adolescent Idiopathic Scoliosis (75% recruiting · 8 trials)

Activity, Motor75%B-ALL (this)75%Achalasia50%Abdominal Cancer25%Acne Scars - Mixed Atrophic 25%
Open-enrollment share among volume-matched conditions near B-ALL

B-ALL lists 6 open slots (75% of 8 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for B-ALL on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. B-ALL is recruiting above its size-band peers.

    6 of 8 indexed trials (75%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates B-ALL research.

    National Cancer Institute (NCI) accounts for 3 of 8 trials (37.5%). 5 distinct sponsors appear on at least one study for this condition label.

  3. Typical B-ALL enrolment sits around 100 participants.

    Median target enrolment is 100 among the 8 trials that report a genuine target (sentinel values excluded). 4 of those (50%) plan for fewer than 100 participants.

  4. B-ALL research is mostly interventional.

    7 interventional and 1 observational studies make up this index (87.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 15

Open and recent trials

8 total, page 1 of 1

RECRUITING Phase 1 126 participants

CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies

National Cancer Institute (NCI)

NCT05442515

RECRUITING Phase 1 108 participants

CD123-Directed T-Cell Therapy for Acute Myelogenous Leukemia (CATCHAML)

St. Jude Children's Research Hospital

NCT04318678

RECRUITING 100 participants

Prospective Evaluation Of Delayed Effects Of Pediatric Car T Cell Therapy

St. Jude Children's Research Hospital

NCT06579469

RECRUITING NA 60 participants

A Study to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-cell Recovery to Guide Management Following Chimeric Antigen Receptor T-cell (CART) Induced Remission in Children and Young Adults With B Lineage Acute Lymphoblastic Leu...

National Cancer Institute (NCI)

NCT05621291

RECRUITING NA 20 participants

Study of Nutrition and Exercise in Adults Hospitalized for Treatment of Acute Lymphoblastic Leukemia (ALL)

University of Chicago

NCT06785324

RECRUITING Early Phase 1 12 participants

Iomab-ACT: A Pilot Study of 131-I Apamistamab Followed by CD19-Targeted CAR T-Cell Therapy for Patients With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia or Diffuse Large B-Cell Lymphoma

Memorial Sloan Kettering Cancer Center

NCT04512716

COMPLETED Phase 1 134 participants

Anti-CD22 Chimeric Receptor T Cells in Pediatric and Young Adults With Recurrent or Refractory CD22-expressing B Cell Malignancies

National Cancer Institute (NCI)

NCT02315612

COMPLETED Phase 1 52 participants

Autologous CD22 CAR T Cells in Adults w/ Recurrent or Refractory B Cell Malignancies

Stanford University

NCT04088890

Phase Distribution

PhaseTrial count
Phase 1 5

Named interventions

Most-linked intervention names on B-ALL records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Fludarabine Drug
2 trials
Cyclophosphamide Drug
2 trials
CD22 CAR Drug
1 trials
CD22-CAR Biological
1 trials
NGS testing Diagnostic test
1 trials
CD19/CD22-CAR-transduced T cells Biological
1 trials
CAR T-cell Biological
1 trials
131-I Apamistamab Drug
1 trials

US sites by state

Facility locations filed on B-ALL trials. A trial with sites in several states counts in each.

Maryland 3 trials
Tennessee 2 trials
California 2 trials
Wisconsin 1 trials
Washington 1 trials
Utah 1 trials
New York 1 trials
New Jersey 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this B-ALL page

8 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This B-ALL condition card totals 8 registered trials; most-linked intervention Fludarabine; top US site state Maryland. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.