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NCT02394587 · ClinicalTrials.gov registry record · NA

MBSR for Pain Catastrophizing in SCD

A NA study of Anemia, Sickle Cell, sponsored by Duke University.

Completed
Registry status
NA
Development phase
60
Enrollment target
1
Study location

NCT02394587 is a NA study of Anemia, Sickle Cell that has completed, run by Duke University. The registered enrollment target is 60 participants, below the 115-participant average among 17 other Anemia, Sickle Cell trials with a reported enrollment target (48% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT02394587, a NA study of Anemia, Sickle Cell, has completed, sponsored by Duke University.

COMPLETED
Registry status
NA
Development phase
60 participants
Enrollment target
1
Study location

Study Summary

Significance: The purpose of this exploratory study is to test the feasibility, accessibility, and effects of a mindfulness-based stress reduction program (MBSR) on reducing pain catastrophizing in persons with sickle cell disease (SCD) and chronic pain. One of the most difficult symptoms for SCD patients to manage is chronic pain. Approximately one-third of SCD patients experience chronic pain, which is associated with pain catastrophizing. Pain catastrophizing is a negative mental state toward pain stimuli and pain experience, and is associated with increased pain severity, pain interference, and lower social functioning, physical functioning, and mental health. There have been no psychobehavioral intervention studies that have attempted to alter the experience of pain catastrophizing in persons with SCD. MBSR is a complementary group-based therapy that emphasizes nonjudgmental awareness of thoughts, feelings, and bodily sensations. With no pharmacological or non-pharmacological treatment for catastrophizing in persons with SCD, MBSR offers a potential solution to this highly significant problem for both SCD patients and providers. This project will be the first randomized controlled trial (RCT) of MBSR to reduce pain catastrophizing, and improve quality of life for SCD patients with chronic pain. Methods: This study will enroll 60 adult patients with SCD and chronic pain from the Duke Adult Sickle Cell Clinic. Patients will be randomized to a MBSR or wait-listed control group. The MBSR group will complete a 6- week, group-based telephonic MBSR program that is administered by a certified MBSR clinician once a week for 90 minutes. MBSR feasibility, acceptability, and effects on pain catastrophizing will be assessed by questionnaires at baseline, week 1, 3, and 6 in both groups. At the end of week 6, 10 randomly selected MBSR participants will complete semi-scripted telephone interviews to help assess intervention acceptability, and the wait-listed control conditio

Conditions Studied

Interventions

  • BEHAVIORAL Mindfulness-based Stress Reduction

Study Locations (1)

North Carolina

  • Duke University School of Nursing - Durham

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2015-04
Est. Completion 2016-01
Phase NA

Sponsor

Duke University

1,725 total trials

What the Registry Record Tells You About NCT02394587

The ClinicalTrials.gov registry entry for NCT02394587 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 115-participant average among 17 other Anemia, Sickle Cell trials with a reported enrollment target (48% lower). The listed sponsor is Duke University, which has 1,725 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Anemia, Sickle Cell appearing as the primary indexed condition, and to 1 intervention - of which Mindfulness-based Stress Reduction is the first listed.

NCT02394587 reports 1 study location spanning 1 distinct geographic area - top geographies include North Carolina.

Frequently Asked Questions

What is clinical trial NCT02394587 about?

NCT02394587 is a clinical study titled "MBSR for Pain Catastrophizing in SCD". Significance: The purpose of this exploratory study is to test the feasibility, accessibility, and effects of a mindfulness-based stress reduction program (MBSR) on reducing pain catastrophizing in persons with sickle cell disease (SCD) and chronic pain. One of the most difficult symptoms for SCD pa...

What is the current status of trial NCT02394587?

This trial is currently completed. It is a NA study. The enrollment target is 60 participants. The study started on 2015-04. Estimated completion is 2016-01.

What conditions does trial NCT02394587 study?

This clinical trial studies the following conditions: Anemia, Sickle Cell.

What interventions are being tested in trial NCT02394587?

The interventions under investigation include: Mindfulness-based Stress Reduction (BEHAVIORAL).

Who is sponsoring clinical trial NCT02394587?

This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02394587 being conducted?

This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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