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NCT07579208 · ClinicalTrials.gov registry record · Phase 1

A Phase1 Clinical Trial Evaluating Locoregional Delivery Of Engineered NK Cells Containing IL13Ra And EGFvIII Chimeric Antigen Receptor (CAR), IL-21 Secretion And Deleted TGF-BetaR2 And NR3C1 In Recurrent Glioblastoma

A Phase 1 study, sponsored by M.D. Anderson Cancer Center.

Not yet
Registry status
Phase 1
Development phase
36
Enrollment target

NCT07579208: Clinical Trial Phase 1 study, sponsored by M.D. Anderson Cancer Center.

NCT07579208 is a Phase 1 study that has not yet begun recruiting, run by M.D. Anderson Cancer Center. The registered enrollment target is 36 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07579208, a Phase 1 study, has not yet begun recruiting, sponsored by M.D. Anderson Cancer Center.

NOT YET RECRUITING
Registry status
Phase 1
Development phase
36 participants
Enrollment target

Study Summary

To find the best method of administering NK cells in patients with recurrent glioblastoma.

Primary Outcome

Incidence of Adverse Events, Graded According to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) Version (v) 5.0

Interventions

  • DRUG NK Cells

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 2026-10-24
Est. Completion 2030-07-30
Phase Phase 1
M.D. Anderson Cancer Center

2,692 total trials

What is known before NCT07579208 opens enrollment

NCT07579208 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower).

The record links to 0 conditions, and to 1 intervention - of which NK Cells is the first listed.

NCT07579208 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07579208 about?

NCT07579208 is a clinical study titled "A Phase1 Clinical Trial Evaluating Locoregional Delivery Of Engineered NK Cells Containing IL13Ra And EGFvIII Chimeric Antigen Receptor (CAR), IL-21 Secretion And Deleted TGF-BetaR2 And NR3C1 In Recurrent Glioblastoma". To find the best method of administering NK cells in patients with recurrent glioblastoma.

What is the current status of trial NCT07579208?

This trial is currently not yet recruiting. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2026-10-24. Estimated completion is 2030-07-30.

What interventions are being tested in trial NCT07579208?

The interventions under investigation include: NK Cells (DRUG).

Who is sponsoring clinical trial NCT07579208?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07579208's enrollment target sits among peer trials

36 1210th of 2000 higher than 743 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07579208, the US trial registry maintained by the National Library of Medicine. NCT07579208 (small enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.