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NCT07546617 · ClinicalTrials.gov registry record
In Vivo Imaging of the Olfactory Epithelium Using Confocal Laser Endomicroscopy
A clinical trial, sponsored by Dartmouth-Hitchcock Medical Center.
- Not yet
- Registry status
- 36
- Enrollment target
NCT07546617: Clinical Trial study, sponsored by Dartmouth-Hitchcock Medical Center.
NCT07546617 is a clinical trial that has not yet begun recruiting, run by Dartmouth-Hitchcock Medical Center. The registered enrollment target is 36 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07546617 has not yet begun recruiting, sponsored by Dartmouth-Hitchcock Medical Center.
- NOT YET RECRUITING
- Registry status
- 36 participants
- Enrollment target
Study Summary
This research is being done to better characterize the part of the nose that helps us smell. Currently, the only ways to study smell loss mostly rely on how people report it, rather than being able to see the underlying structures directly. In this study, we will use a special microscope (Confocal Laser Endomicroscopy (CLE)), originally developed for brain tissue, to look at the part of the nose that helps to detects smell. We hope to identify the tiny structures in that area and see how they might be different in people who have smell loss compared to those who do not.
Primary Outcome
(1) High feasibility (≥85% interpretable images); (2) identifiable CLE signatures associated with OD severity; (3) significant correlations between CLE features, TDI scores, and symptom burden.
Interventions
- OTHER Conventional histologic evaluation
- DEVICE CONVIVO system
- DRUG Fluorescein injection, USP 10%
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2026-07-01 |
| Est. Completion | 2027-07-31 |
What is known before NCT07546617 opens enrollment
NCT07546617 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 36 participants, a relatively small participant target.
The record links to 0 conditions, and to 3 interventions - of which Conventional histologic evaluation is the first listed.
NCT07546617 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07546617 about?
NCT07546617 is a clinical study titled "In Vivo Imaging of the Olfactory Epithelium Using Confocal Laser Endomicroscopy". This research is being done to better characterize the part of the nose that helps us smell. Currently, the only ways to study smell loss mostly rely on how people report it, rather than being able to see the underlying structures directly. In this study, we will use a special microscope (Confocal L...
What is the current status of trial NCT07546617?
This trial is currently not yet recruiting. The enrollment target is 36 participants. The study started on 2026-07-01. Estimated completion is 2027-07-31.
What interventions are being tested in trial NCT07546617?
The interventions under investigation include: Conventional histologic evaluation (OTHER), CONVIVO system (DEVICE), Fluorescein injection, USP 10% (DRUG).
Who is sponsoring clinical trial NCT07546617?
This trial is sponsored by Dartmouth-Hitchcock Medical Center, which has 427 total clinical trials registered on ClinicalTrials.gov.
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