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NCT07430839 · ClinicalTrials.gov registry record
Exercise and Carotid Artery Function in Metabolic Syndrome
A clinical trial of Metabolic Syndrome, sponsored by University of Wisconsin, Madison.
- Recruiting
- Registry status
- 48
- Enrollment target
- 1
- Study location
NCT07430839: Recruiting study of Metabolic Syndrome, sponsored by University of Wisconsin, Madison.
NCT07430839 is a study of Metabolic Syndrome that is actively recruiting participants, run by University of Wisconsin, Madison. The registered enrollment target is 48 participants, below the 1,204-participant average among 102 other Metabolic Syndrome trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07430839, a study of Metabolic Syndrome, is actively recruiting participants, sponsored by University of Wisconsin, Madison.
- RECRUITING
- Registry status
- 48 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to determine 1) if young adults with metabolic syndrome display endothelial dysfunction of the internal carotid artery in a sex-specific fashion and 2) if this endothelial dysfunction can be acutely improved with a single bout of exercise. This will be achieved by testing internal carotid artery function before and after a 30-minute bout of moderate intensity exercise. 48 young adults with and without metabolic syndrome will be enrolled and will be on study for approximately 5.5 hours over 4 study visits.
Primary Outcome
Internal carotid artery cerebral shear-mediated dilation (cSMD) is measured by doppler ultrasound and reported in percentage increase in diameter. A resting baseline period for 5 minutes breathing room air followed by 30 seconds of breathing CO2-mixed air at +9 mmHg PETCO2 used to evoke an increase in blood flow to the ICA.
Conditions Studied
Interventions
- BEHAVIORAL exercise
- DIAGNOSTIC_TEST Diagnostics
- OTHER Inhaled CO2-mixed air
Study Locations (1)
Wisconsin
- University of Wisconsin - Madison
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2025-12-01 |
| Est. Completion | 2027-06-30 |
What NCT07430839 shows while recruiting
NCT07430839 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 1,204-participant average among 102 other Metabolic Syndrome trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Metabolic Syndrome appearing as the primary indexed condition, and to 3 interventions - of which exercise is the first listed.
NCT07430839 reports a single indexed study location in Wisconsin.
Frequently Asked Questions
What is clinical trial NCT07430839 about?
NCT07430839 is a clinical study titled "Exercise and Carotid Artery Function in Metabolic Syndrome". The purpose of this study is to determine 1) if young adults with metabolic syndrome display endothelial dysfunction of the internal carotid artery in a sex-specific fashion and 2) if this endothelial dysfunction can be acutely improved with a single bout of exercise. This will be achieved by testin...
What is the current status of trial NCT07430839?
This trial is currently recruiting. The enrollment target is 48 participants. The study started on 2025-12-01. Estimated completion is 2027-06-30.
What conditions does trial NCT07430839 study?
This clinical trial studies the following conditions: Metabolic Syndrome.
What interventions are being tested in trial NCT07430839?
The interventions under investigation include: exercise (BEHAVIORAL), Diagnostics (DIAGNOSTIC_TEST), Inhaled CO2-mixed air (OTHER).
Who is sponsoring clinical trial NCT07430839?
This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07430839 being conducted?
This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Metabolic Syndrome
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07430839's enrollment target sits among peer trials
48 59th of 102 higher than 43 of 102 other Metabolic Syndrome trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Metabolic Syndrome trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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