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NCT07296991 · ClinicalTrials.gov registry record · NA
VR Stimulation of Exercise Response in Sedentary Humans
A NA study of Metabolic Syndrome and Prolonged Inactivity, sponsored by Wayne State University.
- Recruiting
- Registry status
- NA
- Development phase
- 48
- Enrollment target
- 1
- Study location
NCT07296991: Recruiting NA study of Metabolic Syndrome and Prolonged Inactivity, sponsored by Wayne State University.
NCT07296991 is a NA study of Metabolic Syndrome and Prolonged Inactivity that is actively recruiting participants, run by Wayne State University. The registered enrollment target is 48 participants, below the 1,204-participant average among 102 other Metabolic Syndrome trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07296991, a NA study of Metabolic Syndrome and Prolonged Inactivity, is actively recruiting participants, sponsored by Wayne State University.
- RECRUITING
- Registry status
- NA
- Development phase
- 48 participants
- Enrollment target
- 1
- Study location
Study Summary
Prolonged sedentary conditions contribute to declining health across human populations and cause significant secondary health consequences for many patients whose illnesses or injuries prevent them from exercising. The investigators have demonstrated that in a small animal fruit fly model, genetic stimulation of neurons that promote adrenergic signaling is sufficient to mimic the benefits of exercise training even in sedentary animals. The investigator's pilot work in humans has confirmed that humans respond to Virtual Reality (VR) stimuli that mimic exercise by increasing heart rate and altering heart rate variability in a way consistent with increased adrenergic activity. In this study, the investigators will directly test for the first time whether repeated, controlled exposure to VR stimuli that induce adrenergic activity in sedentary humans can produce adaptive changes to protein expression and endurance performance like those produced by actual exercise in pre-diabetic participants with/without hypertension.
Primary Outcome
Pre-diabetic patients (Blood glucose 100-125 mg/dL, AbA1C 5.7-6.4%) may see improvement in values post-intervention
Conditions Studied
Interventions
- BEHAVIORAL 20 minutes cycling exercise
- BEHAVIORAL Virtual Reality
Study Locations (1)
Michigan
- Wayne State University - Detroit
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2025-09-30 |
| Est. Completion | 2028-08 |
| Phase | NA |
What NCT07296991 shows while recruiting
NCT07296991 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 1,204-participant average among 102 other Metabolic Syndrome trials with a reported enrollment target (96% lower).
The record links to 2 conditions, with Metabolic Syndrome appearing as the primary indexed condition, and to 2 interventions - of which 20 minutes cycling exercise is the first listed.
NCT07296991 reports a single indexed study location in Michigan.
Frequently Asked Questions
What is clinical trial NCT07296991 about?
NCT07296991 is a clinical study titled "VR Stimulation of Exercise Response in Sedentary Humans". Prolonged sedentary conditions contribute to declining health across human populations and cause significant secondary health consequences for many patients whose illnesses or injuries prevent them from exercising. The investigators have demonstrated that in a small animal fruit fly model, genetic s...
What is the current status of trial NCT07296991?
This trial is currently recruiting. It is a NA study. The enrollment target is 48 participants. The study started on 2025-09-30. Estimated completion is 2028-08.
What conditions does trial NCT07296991 study?
This clinical trial studies the following conditions: Metabolic Syndrome, Prolonged Inactivity.
What interventions are being tested in trial NCT07296991?
The interventions under investigation include: 20 minutes cycling exercise (BEHAVIORAL), Virtual Reality (BEHAVIORAL).
Who is sponsoring clinical trial NCT07296991?
This trial is sponsored by Wayne State University, which has 163 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07296991 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Metabolic Syndrome
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07296991's enrollment target sits among peer trials
48 59th of 102 higher than 43 of 102 other Metabolic Syndrome trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Metabolic Syndrome trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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