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NCT07296991 · ClinicalTrials.gov registry record · NA
VR Stimulation of Exercise Response in Sedentary Humans
A NA study of Metabolic Syndrome and Prolonged Inactivity, sponsored by Wayne State University.
- Recruiting
- Registry status
- NA
- Development phase
- 48
- Enrollment target
- 1
- Study location
NCT07296991 is a NA study of Metabolic Syndrome and Prolonged Inactivity that is actively recruiting participants, run by Wayne State University. The registered enrollment target is 48 participants, below the 1,204-participant average among 102 other Metabolic Syndrome trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.
The verdict
NCT07296991, a NA study of Metabolic Syndrome and Prolonged Inactivity, is actively recruiting participants, sponsored by Wayne State University.
- RECRUITING
- Registry status
- NA
- Development phase
- 48 participants
- Enrollment target
- 1
- Study location
Study Summary
Prolonged sedentary conditions contribute to declining health across human populations and cause significant secondary health consequences for many patients whose illnesses or injuries prevent them from exercising. The investigators have demonstrated that in a small animal fruit fly model, genetic stimulation of neurons that promote adrenergic signaling is sufficient to mimic the benefits of exercise training even in sedentary animals. The investigator's pilot work in humans has confirmed that humans respond to Virtual Reality (VR) stimuli that mimic exercise by increasing heart rate and altering heart rate variability in a way consistent with increased adrenergic activity. In this study, the investigators will directly test for the first time whether repeated, controlled exposure to VR stimuli that induce adrenergic activity in sedentary humans can produce adaptive changes to protein expression and endurance performance like those produced by actual exercise in pre-diabetic participants with/without hypertension.
Conditions Studied
Interventions
- BEHAVIORAL 20 minutes cycling exercise
- BEHAVIORAL Virtual Reality
Study Locations (1)
Michigan
- Wayne State University - Detroit
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2025-09-30 |
| Est. Completion | 2028-08 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07296991
The ClinicalTrials.gov registry entry for NCT07296991 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 48 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,204-participant average among 102 other Metabolic Syndrome trials with a reported enrollment target (96% lower). The listed sponsor is Wayne State University, which has 163 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Metabolic Syndrome appearing as the primary indexed condition, and to 2 interventions - of which 20 minutes cycling exercise is the first listed.
NCT07296991 reports 1 study location spanning 1 distinct geographic area - top geographies include Michigan.
Frequently Asked Questions
What is clinical trial NCT07296991 about?
NCT07296991 is a clinical study titled "VR Stimulation of Exercise Response in Sedentary Humans". Prolonged sedentary conditions contribute to declining health across human populations and cause significant secondary health consequences for many patients whose illnesses or injuries prevent them from exercising. The investigators have demonstrated that in a small animal fruit fly model, genetic s...
What is the current status of trial NCT07296991?
This trial is currently recruiting. It is a NA study. The enrollment target is 48 participants. The study started on 2025-09-30. Estimated completion is 2028-08.
What conditions does trial NCT07296991 study?
This clinical trial studies the following conditions: Metabolic Syndrome, Prolonged Inactivity.
What interventions are being tested in trial NCT07296991?
The interventions under investigation include: 20 minutes cycling exercise (BEHAVIORAL), Virtual Reality (BEHAVIORAL).
Who is sponsoring clinical trial NCT07296991?
This trial is sponsored by Wayne State University, which has 163 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07296991 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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