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NCT07388667 · ClinicalTrials.gov registry record · Phase 1
A Clinical Study of MK-4082 in Healthy Overweight Participants (MK-4082-002)
A Phase 1 study of Healthy, sponsored by Merck Sharp & Dohme.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 120
- Enrollment target
- 2
- Study locations
NCT07388667: Recruiting Phase 1 study of Healthy, sponsored by Merck Sharp & Dohme.
NCT07388667 is a Phase 1 study of Healthy that is actively recruiting participants, run by Merck Sharp & Dohme. The registered enrollment target is 120 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (81% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07388667, a Phase 1 study of Healthy, is actively recruiting participants, sponsored by Merck Sharp & Dohme.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 120 participants
- Enrollment target
- 2
- Study locations
Study Summary
Researchers are looking for new weight loss medicines for people with higher body weight. The study medicine, MK-4082, is different from similar weight loss medicines because people take it as a pill instead of an injection. Before giving a study medicine to people with a health condition, researchers first do studies to find a safe dose level (amount) of the study medicine that can be used in future studies. The goals of this study are to learn about: * The safety of MK-4082 and if people tolerate it * What happens to different MK-4082 dose levels in a person's body over time
Primary Outcome
An AE is any untoward medical occurrence in a clinical study participant, temporally associated with the use of study intervention, whether or not considered related to the study intervention. The number of participants who experience an AE will be reported.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG MK-4082
Study Locations (2)
Florida
- QPS-MRA, LLC ( Site 0003) - South Miami
Missouri
- Bio-Kinetic Clinical Applications, LLD dba QPS-MO ( Site 0004) - Springfield
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2026-03-04 |
| Est. Completion | 2026-08-19 |
| Phase | Phase 1 |
What NCT07388667 shows while recruiting
NCT07388667 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (81% lower).
The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT07388667 reports a single indexed study location in Florida, Missouri.
Frequently Asked Questions
What is clinical trial NCT07388667 about?
NCT07388667 is a clinical study titled "A Clinical Study of MK-4082 in Healthy Overweight Participants (MK-4082-002)". Researchers are looking for new weight loss medicines for people with higher body weight. The study medicine, MK-4082, is different from similar weight loss medicines because people take it as a pill instead of an injection. Before giving a study medicine to people with a health condition, researche...
What is the current status of trial NCT07388667?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 120 participants. The study started on 2026-03-04. Estimated completion is 2026-08-19.
What conditions does trial NCT07388667 study?
This clinical trial studies the following conditions: Healthy.
What interventions are being tested in trial NCT07388667?
The interventions under investigation include: Placebo (DRUG), MK-4082 (DRUG).
Who is sponsoring clinical trial NCT07388667?
This trial is sponsored by Merck Sharp & Dohme, which has 558 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07388667 being conducted?
This trial has 2 study locations across Florida, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07388667's enrollment target sits among peer trials
120 182nd of 1090 higher than 896 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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