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NCT02782663 · ClinicalTrials.gov registry record · Phase 2

A Study to Evaluate the Long-Term Efficacy, Safety, and Tolerability of Repeated Administration of Upadacitinib (ABT-494) in Participants With Crohn's Disease

A Phase 2 study of Crohn's Disease (CD), sponsored by AbbVie.

Completed
Registry status
Phase 2
Development phase
107
Enrollment target
20
Study locations

NCT02782663 is a Phase 2 study of Crohn's Disease (CD) that has completed, run by AbbVie. The registered enrollment target is 107 participants, below the 180-participant average among 5 other Crohn's Disease (CD) trials with a reported enrollment target (41% lower). The trial reports 20 study locations across 13 states.

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The verdict

NCT02782663, a Phase 2 study of Crohn's Disease (CD), has completed, sponsored by AbbVie.

COMPLETED
Registry status
Phase 2
Development phase
107 participants
Enrollment target
20
Study locations

Study Summary

This is a open-label extension (OLE) study designed to evaluate the long-term efficacy, safety, and tolerability of Upadacitinib (ABT-494).

Conditions Studied

Interventions

  • DRUG ABT-494

Study Locations (20)

Florida

  • Duplicate_University of Florida - Archer /ID# 150033 - Gainesville
  • The Ctr for Gastro Disorders /ID# 150012 - Hollywood
  • Nature Coast Clinical Research - Inverness /ID# 149975 - Inverness

California

  • UC San Diego Health System /ID# 150041 - La Jolla
  • Univ California, San Francisco /ID# 149987 - San Francisco

Georgia

  • Gastroenterology Associates of Central Georgia, LLC /ID# 149870 - Macon
  • GI Specialists of GA, PC /ID# 150015 - Marietta

Maryland

  • Investigative Clinical Research /ID# 149886 - Annapolis
  • Charm City Research Group /ID# 150040 - Towson

Missouri

  • Kansas City Research Institute /ID# 149888 - Kansas City
  • Washington University-School of Medicine /ID# 149899 - St Louis

New York

  • NYU Langone Long Island Clinical Research Associates /ID# 149976 - Lake Success
  • Weill Cornell Medicine/NYP /ID# 149895 - New York

Kansas

  • Cotton O'Neil Clinical Research Center, Digestive Health /ID# 149900 - Topeka

Kentucky

  • Duplicate_University of Louisville /ID# 149884 - Louisville

Trial Details

FieldValue
Enrollment Target 107 participants
Start Date 2016-05-18
Est. Completion 2025-07-18
Phase Phase 2

Sponsor

AbbVie

526 total trials

What the Registry Record Tells You About NCT02782663

The ClinicalTrials.gov registry entry for NCT02782663 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 107 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 180-participant average among 5 other Crohn's Disease (CD) trials with a reported enrollment target (41% lower). The listed sponsor is AbbVie, which has 526 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Crohn's Disease (CD) appearing as the primary indexed condition, and to 1 intervention - of which ABT-494 is the first listed.

NCT02782663 reports 20 study locations spanning 13 distinct geographic areas - top geographies include Florida, California, Georgia.

Frequently Asked Questions

What is clinical trial NCT02782663 about?

NCT02782663 is a clinical study titled "A Study to Evaluate the Long-Term Efficacy, Safety, and Tolerability of Repeated Administration of Upadacitinib (ABT-494) in Participants With Crohn's Disease". This is a open-label extension (OLE) study designed to evaluate the long-term efficacy, safety, and tolerability of Upadacitinib (ABT-494).

What is the current status of trial NCT02782663?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 107 participants. The study started on 2016-05-18. Estimated completion is 2025-07-18.

What conditions does trial NCT02782663 study?

This clinical trial studies the following conditions: Crohn's Disease (CD).

What interventions are being tested in trial NCT02782663?

The interventions under investigation include: ABT-494 (DRUG).

Who is sponsoring clinical trial NCT02782663?

This trial is sponsored by AbbVie, which has 526 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02782663 being conducted?

This trial has 20 study locations across California, Florida, Georgia, Kansas, Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.