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NCT07335497 · ClinicalTrials.gov registry record · Phase 1

CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

A Phase 1 study of Locally Advanced / Metastatic Solid Tumors, sponsored by Crescent Biopharma.

Recruiting
Registry status
Phase 1
Development phase
290
Enrollment target
5
Study locations

NCT07335497 is a Phase 1 study of Locally Advanced / Metastatic Solid Tumors that is actively recruiting participants, run by Crescent Biopharma. The registered enrollment target is 290 participants. The trial reports 5 study locations across 4 states.

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The verdict

NCT07335497, a Phase 1 study of Locally Advanced / Metastatic Solid Tumors, is actively recruiting participants, sponsored by Crescent Biopharma.

RECRUITING
Registry status
Phase 1
Development phase
290 participants
Enrollment target
5
Study locations

Study Summary

The purpose of this study is to determine the safety and tolerability of monotherapy CR-001 and identify the maximum tolerated dose (MTD), and/or optimal biologic dose and Recommended Phase 2 Dose(s) (RP2D) in participants with locally advanced or metastatic solid tumors.

Interventions

  • DRUG CR-001

Study Locations (5)

Florida

  • Clinical Study Site - Orlando
  • Clinical Study Site - Sarasota

Colorado

  • Clinical Study Site - Denver

Tennessee

  • Clinical Study Site - Nashville

Texas

  • Clinical Study Site - Dallas

Trial Details

FieldValue
Enrollment Target 290 participants
Start Date 2026-02-17
Est. Completion 2029-02
Phase Phase 1

Sponsor

Crescent Biopharma

1 total trials

What the Registry Record Tells You About NCT07335497

The ClinicalTrials.gov registry entry for NCT07335497 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 290 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Crescent Biopharma, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Locally Advanced / Metastatic Solid Tumors appearing as the primary indexed condition, and to 1 intervention - of which CR-001 is the first listed.

NCT07335497 reports 5 study locations spanning 4 distinct geographic areas - top geographies include Florida, Colorado, Tennessee.

Frequently Asked Questions

What is clinical trial NCT07335497 about?

NCT07335497 is a clinical study titled "CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors". The purpose of this study is to determine the safety and tolerability of monotherapy CR-001 and identify the maximum tolerated dose (MTD), and/or optimal biologic dose and Recommended Phase 2 Dose(s) (RP2D) in participants with locally advanced or metastatic solid tumors.

What is the current status of trial NCT07335497?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 290 participants. The study started on 2026-02-17. Estimated completion is 2029-02.

What conditions does trial NCT07335497 study?

This clinical trial studies the following conditions: Locally Advanced / Metastatic Solid Tumors.

What interventions are being tested in trial NCT07335497?

The interventions under investigation include: CR-001 (DRUG).

Who is sponsoring clinical trial NCT07335497?

This trial is sponsored by Crescent Biopharma, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07335497 being conducted?

This trial has 5 study locations across Colorado, Florida, Tennessee, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.