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NCT06414460 · ClinicalTrials.gov registry record · Phase 1
Study of ISM3412 in Participants With Locally Advanced/Metastatic Solid Tumors
A Phase 1 study of Locally Advanced/Metastatic Solid Tumors, sponsored by InSilico Medicine Hong Kong Limited.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 80
- Enrollment target
- 9
- Study locations
NCT06414460 is a Phase 1 study of Locally Advanced/Metastatic Solid Tumors that is actively recruiting participants, run by InSilico Medicine Hong Kong Limited. The registered enrollment target is 80 participants. The trial reports 9 study locations across 9 states.
The verdict
NCT06414460, a Phase 1 study of Locally Advanced/Metastatic Solid Tumors, is actively recruiting participants, sponsored by InSilico Medicine Hong Kong Limited.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 80 participants
- Enrollment target
- 9
- Study locations
Study Summary
The study has consists of two parts, a dose escalation part (Part 1) and a dose selection optimization part (Part 2). The primary objectives of this study are to evaluate the safety and tolerability of ISM3412 in participants with locally advanced/metastatic solid tumors, and to determine the RP2D of ISM3412.
Conditions Studied
Interventions
- DRUG ISM3412
Study Locations (9)
Colorado
- Sarah Cannon Research Institute at HealthONE - Denver
Connecticut
- Smilow Cancer Hospital at Yale New Haven Breast Center - New Haven
Indiana
- Community Cancer Center North - Indianapolis
Tennessee
- SCRI Oncology Partners - Nashville
Texas
- The University of Texas MD Anderson Cancer Center - Houston
Beijing Municipality
- Cancer Hospital Chinese Academy of Medical Sciences - Beijing
Guangdong
- Sun Yat-sen university cancer center - Guangzhou
Jiangsu
- Jiangsu Provincial People's Hospital - Nanjing
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2025-04-25 |
| Est. Completion | 2029-03-31 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06414460
The ClinicalTrials.gov registry entry for NCT06414460 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is InSilico Medicine Hong Kong Limited, which has 3 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Locally Advanced/Metastatic Solid Tumors appearing as the primary indexed condition, and to 1 intervention - of which ISM3412 is the first listed.
NCT06414460 reports 9 study locations spanning 9 distinct geographic areas - top geographies include Colorado, Connecticut, Indiana.
Frequently Asked Questions
What is clinical trial NCT06414460 about?
NCT06414460 is a clinical study titled "Study of ISM3412 in Participants With Locally Advanced/Metastatic Solid Tumors". The study has consists of two parts, a dose escalation part (Part 1) and a dose selection optimization part (Part 2). The primary objectives of this study are to evaluate the safety and tolerability of ISM3412 in participants with locally advanced/metastatic solid tumors, and to determine the RP2D o...
What is the current status of trial NCT06414460?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 80 participants. The study started on 2025-04-25. Estimated completion is 2029-03-31.
What conditions does trial NCT06414460 study?
This clinical trial studies the following conditions: Locally Advanced/Metastatic Solid Tumors.
What interventions are being tested in trial NCT06414460?
The interventions under investigation include: ISM3412 (DRUG).
Who is sponsoring clinical trial NCT06414460?
This trial is sponsored by InSilico Medicine Hong Kong Limited, which has 3 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06414460 being conducted?
This trial has 9 study locations across Colorado, Connecticut, Indiana, Tennessee, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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