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NCT07266948 · ClinicalTrials.gov registry record · Phase 4
Impact of TRYPTYR on a Patient's Quality of Life and Ability to Perform Work
A Phase 4 study of Dry Eye and Eye Diseases, sponsored by Southern College of Optometry.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 40
- Enrollment target
- 3
- Study locations
NCT07266948: Recruiting Phase 4 study of Dry Eye and Eye Diseases, sponsored by Southern College of Optometry.
NCT07266948 is a Phase 4 study of Dry Eye and Eye Diseases that is actively recruiting participants, run by Southern College of Optometry. The registered enrollment target is 40 participants, below the 95-participant average among 41 other Dry Eye trials with a reported enrollment target (58% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07266948, a Phase 4 study of Dry Eye and Eye Diseases, is actively recruiting participants, sponsored by Southern College of Optometry.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 40 participants
- Enrollment target
- 3
- Study locations
Study Summary
This 1-month, 3-visit study will be conducted at the Southern College of Optometry (Memphis, TN), Kannarr Eye Care, LLC (Pittsburg, KS) and Complete Eye Care of Medina (Minneapolis, MN). Adults ≥18 years of age who have been diagnosed with DED for at least 6 months and who are currently symptomatic (Eye Dryness VAS Score ≥40) will be recruited. Subjects will have an abnormal Schirmer test of \<10 mm/5 min. Subjects will also be required to score ≤70 on the IDEEL Quality of Life (QoL) Work domain to ensure that their DED symptoms are significantly impacting their ability to do work.9 Subjects will be required to have corrected distance visual acuity of 20/32 (0.2 logMAR) or better.
Primary Outcome
the ideel quality of life questionnaire will be used to determine if there was an improvement in participant quality of life while using tryptyr
Conditions Studied
Interventions
- DRUG Acoltremon
Study Locations (3)
Kansas
- Kannar Eye Care - Pittsburg
Minnesota
- Complete Eye Care of Medina - Medina
Tennessee
- The Southern College of Optometry - Memphis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2025-11-01 |
| Est. Completion | 2026-03-01 |
| Phase | Phase 4 |
What NCT07266948 shows while recruiting
NCT07266948 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 95-participant average among 41 other Dry Eye trials with a reported enrollment target (58% lower).
The record links to 3 conditions, with Dry Eye appearing as the primary indexed condition, and to 1 intervention - of which Acoltremon is the first listed.
NCT07266948 reports a single indexed study location in Kansas, Minnesota, Tennessee.
Frequently Asked Questions
What is clinical trial NCT07266948 about?
NCT07266948 is a clinical study titled "Impact of TRYPTYR on a Patient's Quality of Life and Ability to Perform Work". This 1-month, 3-visit study will be conducted at the Southern College of Optometry (Memphis, TN), Kannarr Eye Care, LLC (Pittsburg, KS) and Complete Eye Care of Medina (Minneapolis, MN). Adults ≥18 years of age who have been diagnosed with DED for at least 6 months and who are currently symptomatic ...
What is the current status of trial NCT07266948?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 40 participants. The study started on 2025-11-01. Estimated completion is 2026-03-01.
What conditions does trial NCT07266948 study?
This clinical trial studies the following conditions: Dry Eye, Eye Diseases, Eyes Dry Chronic.
What interventions are being tested in trial NCT07266948?
The interventions under investigation include: Acoltremon (DRUG).
Who is sponsoring clinical trial NCT07266948?
This trial is sponsored by Southern College of Optometry, which has 11 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07266948 being conducted?
This trial has 3 study locations across Kansas, Minnesota, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT07266948's enrollment target sits among peer trials
40 24th of 41 higher than 16 of 41 other Dry Eye trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Dry Eye trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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