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NCT06565650 · ClinicalTrials.gov registry record · Phase 4
A Study to Evaluate Corneal Endothelial Cell Density (ECD) in Subjects With Dry Eye Disease (DED) Administering Miebo® (Perfluorohexyloctane Ophthalmic Solution) for 12 Months.
A Phase 4 study of Dry Eye, sponsored by Bausch & Lomb Incorporated.
- Active
- Registry status
- Phase 4
- Development phase
- 216
- Enrollment target
- 12
- Study locations
NCT06565650: Active Phase 4 study of Dry Eye, sponsored by Bausch & Lomb Incorporated.
NCT06565650 is a Phase 4 study of Dry Eye that is active but no longer recruiting, run by Bausch & Lomb Incorporated. The registered enrollment target is 216 participants, above the 90-participant average among 41 other Dry Eye trials with a reported enrollment target (140% higher). The trial reports 12 study locations across 7 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06565650, a Phase 4 study of Dry Eye, is active but no longer recruiting, sponsored by Bausch & Lomb Incorporated.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 4
- Development phase
- 216 participants
- Enrollment target
- 12
- Study locations
Study Summary
A Randomized, Multicenter, Double-Masked, Saline-Controlled Trial to Evaluate Corneal Endothelial Cell Density in Subjects With Dry Eye Disease Administering Miebo® (Perfluorohexyloctane Ophthalmic Solution) for 12 Months
Primary Outcome
Mean change from baseline in ECD in the study eye at the Month 3 and Month 12 Visits
Conditions Studied
Interventions
- DRUG Saline
- DRUG Miebo
Study Locations (12)
California
- Site 101 - Glendale
- Site 112 - Murrieta
- Site 102 - Newport Beach
- Site 109 - Rancho Cordova
- Site 106 - Torrance
Missouri
- Site 110 - Kansas City
- Site 104 - St Louis
Florida
- Site 113 - Delray Beach
Georgia
- Site 107 - Morrow
Indiana
- Site 105 - Carmel
North Carolina
- Site 108 - Asheville
Tennessee
- Site 103 - Memphis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 216 participants |
| Start Date | 2024-07-31 |
| Est. Completion | 2025-11 |
| Phase | Phase 4 |
What the registry record for NCT06565650 still lists
NCT06565650 is an interventional study that assigns participants to a tested intervention. The registered 216 participants enrollment target is mid-sized for trials with a published cap, above the 90-participant average among 41 other Dry Eye trials with a reported enrollment target (140% higher).
The record links to 1 condition, with Dry Eye appearing as the primary indexed condition, and to 2 interventions - of which Saline is the first listed.
NCT06565650 lists 12 locations in 7 states (California, Missouri, Florida).
Frequently Asked Questions
What is clinical trial NCT06565650 about?
NCT06565650 is a clinical study titled "A Study to Evaluate Corneal Endothelial Cell Density (ECD) in Subjects With Dry Eye Disease (DED) Administering Miebo® (Perfluorohexyloctane Ophthalmic Solution) for 12 Months.". A Randomized, Multicenter, Double-Masked, Saline-Controlled Trial to Evaluate Corneal Endothelial Cell Density in Subjects With Dry Eye Disease Administering Miebo® (Perfluorohexyloctane Ophthalmic Solution) for 12 Months
What is the current status of trial NCT06565650?
This trial is currently active not recruiting. It is a Phase 4 study. The enrollment target is 216 participants. The study started on 2024-07-31. Estimated completion is 2025-11.
What conditions does trial NCT06565650 study?
This clinical trial studies the following conditions: Dry Eye.
What interventions are being tested in trial NCT06565650?
The interventions under investigation include: Saline (DRUG), Miebo (DRUG).
Who is sponsoring clinical trial NCT06565650?
This trial is sponsored by Bausch & Lomb Incorporated, which has 174 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06565650 being conducted?
This trial has 12 study locations across California, Florida, Georgia, Indiana, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Dry Eye
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06565650's enrollment target sits among peer trials
216 4th of 41 higher than 38 of 41 other Dry Eye trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Dry Eye trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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