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NCT07241117 · ClinicalTrials.gov registry record · Phase 4
CHEST: A Collaboration With Community HEalth Centers to Implement SmarT for Asthma
A Phase 4 study of Moderate to Severe Asthma, sponsored by Washington University School of Medicine.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 2,000
- Enrollment target
- 7
- Study locations
NCT07241117: Recruiting Phase 4 study of Moderate to Severe Asthma, sponsored by Washington University School of Medicine.
NCT07241117 is a Phase 4 study of Moderate to Severe Asthma that is actively recruiting participants, run by Washington University School of Medicine. The registered enrollment target is 2,000 participants, above the 128-participant average among 3 other Moderate to Severe Asthma trials with a reported enrollment target (1463% higher). The trial reports 7 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07241117, a Phase 4 study of Moderate to Severe Asthma, is actively recruiting participants, sponsored by Washington University School of Medicine.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 2,000 participants
- Enrollment target
- 7
- Study locations
Study Summary
Purpose: This study aims to improve asthma care by helping clinicians at community health centers prescribe a guideline-recommended treatment called SMART (Single Maintenance and Reliever Therapy). The investigators will provide training and resources to clinicians, give feedback on prescribing patterns, and offer educational tools for patients and providers. The investigators will roll out these resources in stages across clinics. The study will measure how well the program helps clinicians prescribe SMART therapy and whether it reduces asthma exacerbations in patients.
Primary Outcome
A clinic-level assessment of the SMART implementation bundle with the endpoint of between-group difference in the proportion of SMART-recommended asthma encounters, wherein SMART was the prescribed inhaler regimen. Patient encounters wherein any diagnosis of asthma was coded in patients ≥12 years old will be queried. Asthma encounters will then be in a binary fashion, as either "SMART- non-recommended" or "SMART- recommended" based on asthma exacerbation history and currently prescribed maintena
Conditions Studied
Interventions
- BEHAVIORAL Implementation bundle
Study Locations (7)
Missouri
- Affinia healthcare, 2220 Lemp Ave - St Louis
- Affinia healthcare, 1717 Biddle Street - St Louis
- Affinia healthcare, 4414 North Florissant Avenue - St Louis
- Family Care Heath Center, 4352 Manchester Ave - St Louis
- Washington University in St. Louis School of Medicine - St Louis
- Family Care Heath Center, 401 Holly Hills Ave - St Louis
- Affinia healthcare, 3396 Pershall Road, - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,000 participants |
| Start Date | 2026-01-06 |
| Est. Completion | 2028-11-15 |
| Phase | Phase 4 |
What NCT07241117 shows while recruiting
NCT07241117 is an interventional study that assigns participants to a tested intervention. Its 2,000 participants enrollment target places it among the larger protocols in the corpus, above the 128-participant average among 3 other Moderate to Severe Asthma trials with a reported enrollment target (1463% higher).
The record links to 1 condition, with Moderate to Severe Asthma appearing as the primary indexed condition, and to 1 intervention - of which Implementation bundle is the first listed.
NCT07241117 lists 7 locations in 1 state (Missouri).
Frequently Asked Questions
What is clinical trial NCT07241117 about?
NCT07241117 is a clinical study titled "CHEST: A Collaboration With Community HEalth Centers to Implement SmarT for Asthma". Purpose: This study aims to improve asthma care by helping clinicians at community health centers prescribe a guideline-recommended treatment called SMART (Single Maintenance and Reliever Therapy). The investigators will provide training and resources to clinicians, give feedback on prescribing pat...
What is the current status of trial NCT07241117?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 2,000 participants. The study started on 2026-01-06. Estimated completion is 2028-11-15.
What conditions does trial NCT07241117 study?
This clinical trial studies the following conditions: Moderate to Severe Asthma.
What interventions are being tested in trial NCT07241117?
The interventions under investigation include: Implementation bundle (BEHAVIORAL).
Who is sponsoring clinical trial NCT07241117?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07241117 being conducted?
This trial has 7 study locations across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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