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NCT07221240 · ClinicalTrials.gov registry record · Phase 1
Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Amisodin in Healthy Adult Subjects With Amyotrophic Lateral Sclerosis
A Phase 1 study of Amyotrophic Lateral Sclerosis, sponsored by PRG Science & Technology Co..
- Recruiting
- Registry status
- Phase 1
- Development phase
- 48
- Enrollment target
- 1
- Study location
NCT07221240: Recruiting Phase 1 study of Amyotrophic Lateral Sclerosis, sponsored by PRG Science & Technology Co..
NCT07221240 is a Phase 1 study of Amyotrophic Lateral Sclerosis that is actively recruiting participants, run by PRG Science & Technology Co.. The registered enrollment target is 48 participants, below the 897-participant average among 102 other Amyotrophic Lateral Sclerosis trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07221240, a Phase 1 study of Amyotrophic Lateral Sclerosis, is actively recruiting participants, sponsored by PRG Science & Technology Co..
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 48 participants
- Enrollment target
- 1
- Study location
Study Summary
Researchers will evaluate the safety, tolerability, and pharmacokinetics (PK) of orally administered Amisodin in healthy adult subjects through a randomized, double-blind, placebo-controlled Phase 1 study consisting of two parts: single ascending dose (SAD) and multiple ascending dose (MAD). The food effect will be assessed in one cohort in Part1. Approximately 48 healthy, adult subjects are planned to be enrolled in total. Subjects will participate in only one part and one cohort.
Primary Outcome
To evaluate the safety and tolerability of a single ascending dose of Amisodin in healthy adult subjects.
Conditions Studied
Interventions
- OTHER Placebo
- DRUG Amisodin
Study Locations (1)
Maryland
- Pharmaron, Inc. - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2025-10-01 |
| Est. Completion | 2026-07-03 |
| Phase | Phase 1 |
What NCT07221240 shows while recruiting
NCT07221240 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 897-participant average among 102 other Amyotrophic Lateral Sclerosis trials with a reported enrollment target (95% lower).
The record links to 1 condition, with Amyotrophic Lateral Sclerosis appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT07221240 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT07221240 about?
NCT07221240 is a clinical study titled "Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Amisodin in Healthy Adult Subjects With Amyotrophic Lateral Sclerosis". Researchers will evaluate the safety, tolerability, and pharmacokinetics (PK) of orally administered Amisodin in healthy adult subjects through a randomized, double-blind, placebo-controlled Phase 1 study consisting of two parts: single ascending dose (SAD) and multiple ascending dose (MAD). The foo...
What is the current status of trial NCT07221240?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 48 participants. The study started on 2025-10-01. Estimated completion is 2026-07-03.
What conditions does trial NCT07221240 study?
This clinical trial studies the following conditions: Amyotrophic Lateral Sclerosis.
What interventions are being tested in trial NCT07221240?
The interventions under investigation include: Placebo (OTHER), Amisodin (DRUG).
Who is sponsoring clinical trial NCT07221240?
This trial is sponsored by PRG Science & Technology Co., which has 3 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07221240 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Amyotrophic Lateral Sclerosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07221240's enrollment target sits among peer trials
48 56th of 102 higher than 47 of 102 other Amyotrophic Lateral Sclerosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Amyotrophic Lateral Sclerosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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