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NCT05279755 · ClinicalTrials.gov registry record · Phase 1

A Study to Evaluate the Safety and Pharmacokinetics of Single and Multiple Doses of Prosetin in Healthy Volunteers and Participants With ALS

A Phase 1 study of Amyotrophic Lateral Sclerosis, sponsored by ProJenX.

Recruiting
Registry status
Phase 1
Development phase
72
Enrollment target
4
Study locations

NCT05279755 is a Phase 1 study of Amyotrophic Lateral Sclerosis that is actively recruiting participants, run by ProJenX. The registered enrollment target is 72 participants, below the 897-participant average among 102 other Amyotrophic Lateral Sclerosis trials with a reported enrollment target (92% lower). The trial reports 4 study locations across 4 states.

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The verdict

NCT05279755, a Phase 1 study of Amyotrophic Lateral Sclerosis, is actively recruiting participants, sponsored by ProJenX.

RECRUITING
Registry status
Phase 1
Development phase
72 participants
Enrollment target
4
Study locations

Study Summary

The primary purpose of this study is to evaluate the safety and tolerability of prosetin in healthy volunteers and participants with ALS.

Interventions

  • DRUG placebo
  • DRUG prosetin

Study Locations (4)

Massachusetts

  • Massachusetts General Hospital - Boston

Texas

  • Worldwide Clinical Trials Early Phase Services - San Antonio

Quebec

  • The Neuro - Montréal Neurological Institute-Hospital - Montreal

Utrecht

  • University Medical Center Utrecht - Utrecht

Trial Details

FieldValue
Enrollment Target 72 participants
Start Date 2022-02-26
Est. Completion 2026-10-31
Phase Phase 1

Sponsor

ProJenX

1 total trials

What the Registry Record Tells You About NCT05279755

The ClinicalTrials.gov registry entry for NCT05279755 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 72 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 897-participant average among 102 other Amyotrophic Lateral Sclerosis trials with a reported enrollment target (92% lower). The listed sponsor is ProJenX, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Amyotrophic Lateral Sclerosis appearing as the primary indexed condition, and to 2 interventions - of which placebo is the first listed.

NCT05279755 reports 4 study locations spanning 4 distinct geographic areas - top geographies include Massachusetts, Texas, Quebec.

Frequently Asked Questions

What is clinical trial NCT05279755 about?

NCT05279755 is a clinical study titled "A Study to Evaluate the Safety and Pharmacokinetics of Single and Multiple Doses of Prosetin in Healthy Volunteers and Participants With ALS". The primary purpose of this study is to evaluate the safety and tolerability of prosetin in healthy volunteers and participants with ALS.

What is the current status of trial NCT05279755?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 72 participants. The study started on 2022-02-26. Estimated completion is 2026-10-31.

What conditions does trial NCT05279755 study?

This clinical trial studies the following conditions: Amyotrophic Lateral Sclerosis.

What interventions are being tested in trial NCT05279755?

The interventions under investigation include: placebo (DRUG), prosetin (DRUG).

Who is sponsoring clinical trial NCT05279755?

This trial is sponsored by ProJenX, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05279755 being conducted?

This trial has 4 study locations across Massachusetts, Texas, Quebec, Utrecht. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.