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RECRUITING Phase 3

CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis

NCT07207811 · View on ClinicalTrials.gov ↗

Study Summary

This study will find out if a new medicine called NNC6019-0001 can help reduce the risk of heart-related death and illness in participants with a condition called transthyretin amyloid cardiomyopathy (ATTR-CM), which affects the heart. Participants will either receive NNC6019-0001 or a placebo (a treatment with no active medicine), and which one they get is decided by chance. Everyone in the study will continue receiving their usual heart treatments as recommended by their doctor.

Interventions

  • DRUG NNC6019-0001
  • DRUG Placebo (NNC6019-0001)

Study Locations (20)

California

  • University of California San Diego (UCSD) - Sulpizio Cardiovascular Center (SCVC) — La Jolla
  • Keck School of Medicine USC - Healthcare Consultation Center 2 (HCCII) — Los Angeles
  • Cedars-Sinai Medical Center - Samuel Oschin Comprehensive Cancer Institute — Los Angeles
  • UCI Medical Center — Orange
  • Profound Research LLC at Southern California Heart Specialists — Pasadena
  • University of California, San Francisco Medical Center — San Francisco
  • Northbay Cardiology Inc. — Santa Rosa
  • Lucile Packard Children's Hospital — Stanford

Illinois

  • Northwestern University Clinical and Translational Sciences Institute — Chicago
  • The University of Chicago Medicine — Chicago
  • Endeavor Health - Glenbrook Hospital — Glenview

Arizona

  • Mayo Clinic Hospital — Phoenix

Connecticut

  • Yale University School of Medicine — New Haven

District of Columbia

  • MedStar Heart & Vascular Institute (MHVI) - MedStar Washington Hospital Center — Washington D.C.

Florida

  • UF Health Heart and Vascular Hospital — Gainesville

Georgia

  • Northeast Georgia Heart Center, Pc (Nghc) — Gainesville

Hawaii

  • The Queen's Medical Center — Honolulu

Trial Details

FieldValue
Enrollment Target 1,280 participants
Start Date 2025-10-02
Est. Completion 2029-06-29
Phase Phase 3

Sponsor

Novo Nordisk A/S

189 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07207811

The ClinicalTrials.gov registry entry for NCT07207811 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 1,280 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novo Nordisk A/S, which has 189 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Transthyretin Amyloid Cardiomyopathy (ATTR CM) appearing as the primary indexed condition, and to 2 interventions — of which NNC6019-0001 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07207811 reports 20 study locations spanning 11 distinct geographic areas — top geographies include California, Illinois, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07207811 about?

NCT07207811 is a clinical study titled "CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis". This study will find out if a new medicine called NNC6019-0001 can help reduce the risk of heart-related death and illness in participants with a condition called transthyretin amyloid cardiomyopathy (ATTR-CM), which affects the heart. Participants will either receive NNC6019-0001 or a placebo (a tr...

What is the current status of trial NCT07207811?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 1,280 participants. The study started on 2025-10-02. Estimated completion is 2029-06-29.

What conditions does trial NCT07207811 study?

This clinical trial studies the following conditions: Transthyretin Amyloid Cardiomyopathy (ATTR CM). These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07207811?

The interventions under investigation include: NNC6019-0001 (DRUG), Placebo (NNC6019-0001) (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07207811?

This trial is sponsored by Novo Nordisk A/S, which has 189 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07207811 being conducted?

This trial has 20 study locations across Arizona, California, Connecticut, District of Columbia, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial