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NCT07001800 · ClinicalTrials.gov registry record · Phase 2
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study
A Phase 2 study of Moderate Aortic Valve Stenosis, sponsored by Kardigan.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 1,276
- Enrollment target
- 20
- Study locations
NCT07001800 is a Phase 2 study of Moderate Aortic Valve Stenosis that is actively recruiting participants, run by Kardigan. The registered enrollment target is 1,276 participants. The trial reports 20 study locations across 6 states.
The verdict
NCT07001800, a Phase 2 study of Moderate Aortic Valve Stenosis, is actively recruiting participants, sponsored by Kardigan.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 1,276 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to evaluate if ataciguat slows the progression of moderate calcific aortic valve stenosis in adults.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Ataciguat
Study Locations (20)
Florida
- HCA Florida - JFK Hospital - Atlantis
- New Generation of Medical Research - Hialeah
- Memorial Healthcare System - Hollywood
- Jacksonville Center for Clinical Research - Jacksonville
- University of Miami - Miami
- New Generation of Medical Research - Naples - Naples
- Sarasota Memorial Hospital - Sarasota
- University of South Florida - Tampa
California
- National Heart Institute - Beverly Hills
- Hoag Memorial Hospital Presbyterian - Newport Beach
- Profound Research LLC at Southern California Heart Specialists - Pasadena
- University of California, San Francisco (UCSF) - Medical Center - San Francisco
- Lundquist Institute for Biomedical Innovation at Harbor UCLA Medical Center - Torrance
Illinois
- Northwestern University The Feinberg School of Medicine - Chicago
- NorthShore University Health System - Glenview
- Midwest Cardiovascular Institute - Naperville
Alabama
- University of Alabama at Birmingham (UAB) - Medical Center - Birmingham
- Heart Center Research LLC - Huntsville
Arizona
- Onyx Clinical Research - Peoria - Peoria
Georgia
- Wellstar Kennestone Hospital - Marietta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,276 participants |
| Start Date | 2025-06-27 |
| Est. Completion | 2030-09-30 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07001800
The ClinicalTrials.gov registry entry for NCT07001800 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 1,276 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Kardigan, which has 4 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Moderate Aortic Valve Stenosis appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT07001800 reports 20 study locations spanning 6 distinct geographic areas - top geographies include Florida, California, Illinois.
Frequently Asked Questions
What is clinical trial NCT07001800 about?
NCT07001800 is a clinical study titled "Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study". The purpose of this study is to evaluate if ataciguat slows the progression of moderate calcific aortic valve stenosis in adults.
What is the current status of trial NCT07001800?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 1,276 participants. The study started on 2025-06-27. Estimated completion is 2030-09-30.
What conditions does trial NCT07001800 study?
This clinical trial studies the following conditions: Moderate Aortic Valve Stenosis.
What interventions are being tested in trial NCT07001800?
The interventions under investigation include: Placebo (DRUG), Ataciguat (DRUG).
Who is sponsoring clinical trial NCT07001800?
This trial is sponsored by Kardigan, which has 4 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07001800 being conducted?
This trial has 20 study locations across Alabama, Arizona, California, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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