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NCT06260709 · ClinicalTrials.gov registry record · Phase 2
A Research Study to Look at Long-term Treatment With a Medicine Called NNC6019-0001 for People Who Have Heart Failure Due to Transthyretin Amyloidosis
A Phase 2 study of Transthyretin Amyloid Cardiomyopathy (ATTR CM), sponsored by Novo Nordisk A/S.
- Active
- Registry status
- Phase 2
- Development phase
- 80
- Enrollment target
- 20
- Study locations
NCT06260709: Active Phase 2 study of Transthyretin Amyloid Cardiomyopathy (ATTR CM), sponsored by Novo Nordisk A/S.
NCT06260709 is a Phase 2 study of Transthyretin Amyloid Cardiomyopathy (ATTR CM) that is active but no longer recruiting, run by Novo Nordisk A/S. The registered enrollment target is 80 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (40% lower). The trial reports 20 study locations across 9 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06260709, a Phase 2 study of Transthyretin Amyloid Cardiomyopathy (ATTR CM), is active but no longer recruiting, sponsored by Novo Nordisk A/S.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 80 participants
- Enrollment target
- 20
- Study locations
Study Summary
This study will test a medicine, NNC6019-0001, for people who have a heart disease due to TTR amyloidosis. It will look at how safe this medicine is in the long term and if it can reduce symptoms of a heart disease due to TTR amyloidosis, such as heart failure. It is an extension to a study called "A research study to look at how a new medicine called NNC6019-0001 works and how safe it is for people who have a heart disease due to TTR amyloidosis". Only participants who have completed that study will be invited for this new study. Participants will get NNC6019-0001, regardless of whether they got placebo or NNC6019-0001 in the first study. The study will last for up to 157 weeks (36 months/3 years).
Primary Outcome
Measured as events.
Conditions Studied
Interventions
- DRUG NNC6019-0001
Study Locations (20)
Other
- II. interni klinika VFN - Kardiologie a angiologie - Prague
- Ap-Hp-Hopital Henri Mondor - Créteil
- Centre Hospitalier Universitaire de Toulouse-Hopital Rangueil-1 - Toulouse
- UniklinikHeidelberg - Innere Med. III - Kardiologie, Angiologie, Pneumologie - Heidelberg
- Universitätsklinik Heidelberg Innere Medizin III Kardiologie, Angiologie, Pneumologie - Heidelberg
- LMU Klinikum München Klinik und Poliklinik 1 - München
- Uniklinik Münster, Klinik für Kardiologie I - Münster
- Universitätsklinikum Münster - Klinik für Kardiologie I - Münster
- Universitatsklinikum Wurzburg AöR - Würzburg
- Universitatsklinikum Würzburg - Zentrum für Herzinsuffizienz - Würzburg
California
- Cedars-Sinai Medical Center_Los Angeles - Los Angeles
- Stanford Hlth Cre-Boswell Clin - Stanford
Illinois
- NW Univ-Bluhm Cardiovasc Inst - Chicago
- NW Univ-Bluhm Cardiovasc Inst - Evanston
Arizona
- Mayo Clinic Arizona - Phoenix
Florida
- Mayo Clinic Jacksonville - Jacksonville
Maryland
- Univ of MD Schl of Med - Baltimore
Minnesota
- Mayo Clinic Rochester - Rochester
Alberta
- University of Calgary_Cardiology - Calgary
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2024-02-20 |
| Est. Completion | 2028-08-15 |
| Phase | Phase 2 |
What the registry record for NCT06260709 still lists
NCT06260709 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (40% lower).
The record links to 1 condition, with Transthyretin Amyloid Cardiomyopathy (ATTR CM) appearing as the primary indexed condition, and to 1 intervention - of which NNC6019-0001 is the first listed.
NCT06260709 names 20 study sites across 9 states, led by Other, California, Illinois.
Frequently Asked Questions
What is clinical trial NCT06260709 about?
NCT06260709 is a clinical study titled "A Research Study to Look at Long-term Treatment With a Medicine Called NNC6019-0001 for People Who Have Heart Failure Due to Transthyretin Amyloidosis". This study will test a medicine, NNC6019-0001, for people who have a heart disease due to TTR amyloidosis. It will look at how safe this medicine is in the long term and if it can reduce symptoms of a heart disease due to TTR amyloidosis, such as heart failure. It is an extension to a study called "...
What is the current status of trial NCT06260709?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 80 participants. The study started on 2024-02-20. Estimated completion is 2028-08-15.
What conditions does trial NCT06260709 study?
This clinical trial studies the following conditions: Transthyretin Amyloid Cardiomyopathy (ATTR CM).
What interventions are being tested in trial NCT06260709?
The interventions under investigation include: NNC6019-0001 (DRUG).
Who is sponsoring clinical trial NCT06260709?
This trial is sponsored by Novo Nordisk A/S, which has 431 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06260709 being conducted?
This trial has 20 study locations across Arizona, California, Florida, Illinois, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06260709's enrollment target sits among peer trials
80 842nd of 2000 higher than 1,117 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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