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NCT07201558 · ClinicalTrials.gov registry record · Phase 1
Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants
A Phase 1 study of Rheumatoid Arthritis and Systemic Lupus Erythematosus, sponsored by AstraZeneca.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 48
- Enrollment target
- 19
- Study locations
NCT07201558: Recruiting Phase 1 study of Rheumatoid Arthritis and Systemic Lupus Erythematosus, sponsored by AstraZeneca.
NCT07201558 is a Phase 1 study of Rheumatoid Arthritis and Systemic Lupus Erythematosus that is actively recruiting participants, run by AstraZeneca. The registered enrollment target is 48 participants, below the 4,690-participant average among 197 other Rheumatoid Arthritis trials with a reported enrollment target (99% lower). The trial reports 19 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07201558, a Phase 1 study of Rheumatoid Arthritis and Systemic Lupus Erythematosus, is actively recruiting participants, sponsored by AstraZeneca.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 48 participants
- Enrollment target
- 19
- Study locations
Study Summary
This open-label, Phase I study will assess the safety and tolerability of surovatamig and characterise its PK and PD following subcutaneous administration to participants with RA or SLE.
Primary Outcome
Number and percentage of participants with adverse events (AEs), serious adverse events (SAEs) and adverse events of special interest (AESIs)
Conditions Studied
Interventions
- BIOLOGICAL Surovatamig
Study Locations (19)
Other
- Research Site - Birtinya
- Research Site - Clayton
- Research Site - Antwerp
- Research Site - Porto Alegre
- Research Site - Beijing
- Research Site - Nanjing
- Research Site - Bonn
- Research Site - Mainz
- Research Site - München
- Research Site - Barcelona
- Research Site - Córdoba
- Research Site - Madrid
- Research Site - Kaohsiung City
- Research Site - Kyiv
- Research Site - Ternopil
- Research Site - Vinnytsia
Alabama
- Research Site - Birmingham
California
- Research Site - Fullerton
Texas
- Research Site - Allen
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2025-12-02 |
| Est. Completion | 2028-06-27 |
| Phase | Phase 1 |
What NCT07201558 shows while recruiting
NCT07201558 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 4,690-participant average among 197 other Rheumatoid Arthritis trials with a reported enrollment target (99% lower).
The record links to 2 conditions, with Rheumatoid Arthritis appearing as the primary indexed condition, and to 1 intervention - of which Surovatamig is the first listed.
NCT07201558 lists 19 locations in 4 states (Other, Alabama, California).
Frequently Asked Questions
What is clinical trial NCT07201558 about?
NCT07201558 is a clinical study titled "Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants". This open-label, Phase I study will assess the safety and tolerability of surovatamig and characterise its PK and PD following subcutaneous administration to participants with RA or SLE.
What is the current status of trial NCT07201558?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 48 participants. The study started on 2025-12-02. Estimated completion is 2028-06-27.
What conditions does trial NCT07201558 study?
This clinical trial studies the following conditions: Rheumatoid Arthritis, Systemic Lupus Erythematosus.
What interventions are being tested in trial NCT07201558?
The interventions under investigation include: Surovatamig (BIOLOGICAL).
Who is sponsoring clinical trial NCT07201558?
This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07201558 being conducted?
This trial has 19 study locations across Alabama, California, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT07201558's enrollment target sits among peer trials
48 143rd of 197 higher than 54 of 197 other Rheumatoid Arthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Rheumatoid Arthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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