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NCT05197530 · ClinicalTrials.gov registry record · Phase 1
Imaging of Lymphatic Vessels in People with Rheumatoid Arthritis (RA)
A Phase 1 study of Rheumatoid Arthritis, sponsored by University of Rochester.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT05197530: Recruiting Phase 1 study of Rheumatoid Arthritis, sponsored by University of Rochester.
NCT05197530 is a Phase 1 study of Rheumatoid Arthritis that is actively recruiting participants, run by University of Rochester. The registered enrollment target is 40 participants, below the 4,690-participant average among 197 other Rheumatoid Arthritis trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05197530, a Phase 1 study of Rheumatoid Arthritis, is actively recruiting participants, sponsored by University of Rochester.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
Lymphatic transport was previously examined by these investigators using Near InfraRed Indocyanine Green fluorescence imaging (NIR-ICG) of the upper extremities. They established reliable and reproducible methodologies in RA patients. The purpose of this phase 2 pilot is to study RA disease progression and effectiveness as well as the mechanism of action of clinical interventions using established NIR-ICG methodologies in previous studies.
Primary Outcome
The change in Indocyanine Green signal intensity (arbitrary units) over time is measured by observing the fluorescence using the Multispectral Imaging System. The MSImager software analyses the signal intensity. This outcome measure will be quantified for both early RA and late RA subjects.
Conditions Studied
Interventions
- DRUG Indocyanine green
- DEVICE MultiSpectral Imaging System
Study Locations (1)
New York
- University of Rochester - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2021-12-30 |
| Est. Completion | 2025-12 |
| Phase | Phase 1 |
What NCT05197530 shows while recruiting
NCT05197530 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 4,690-participant average among 197 other Rheumatoid Arthritis trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Rheumatoid Arthritis appearing as the primary indexed condition, and to 2 interventions - of which Indocyanine green is the first listed.
NCT05197530 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT05197530 about?
NCT05197530 is a clinical study titled "Imaging of Lymphatic Vessels in People with Rheumatoid Arthritis (RA)". Lymphatic transport was previously examined by these investigators using Near InfraRed Indocyanine Green fluorescence imaging (NIR-ICG) of the upper extremities. They established reliable and reproducible methodologies in RA patients. The purpose of this phase 2 pilot is to study RA disease progress...
What is the current status of trial NCT05197530?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2021-12-30. Estimated completion is 2025-12.
What conditions does trial NCT05197530 study?
This clinical trial studies the following conditions: Rheumatoid Arthritis.
What interventions are being tested in trial NCT05197530?
The interventions under investigation include: Indocyanine green (DRUG), MultiSpectral Imaging System (DEVICE).
Who is sponsoring clinical trial NCT05197530?
This trial is sponsored by University of Rochester, which has 636 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05197530 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05197530's enrollment target sits among peer trials
40 148th of 197 higher than 48 of 197 other Rheumatoid Arthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Rheumatoid Arthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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