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RECRUITING Phase 1

Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer

NCT07181161 · View on ClinicalTrials.gov ↗

Study Summary

The main purpose of this study is to assess the safety and tolerability of AZD0516 as monotherapy and/or in combination with other anti-cancer agents for treatment of metastatic prostate cancer.

Conditions Studied

Interventions

  • DRUG AZD9574
  • DRUG AZD0516

Study Locations (20)

Other

  • Research Site — Barretos
  • Research Site — Porto Alegre
  • Research Site — São Paulo
  • Research Site — Changsha
  • Research Site — Chengdu
  • Research Site — Wuhan
  • Research Site — Lyon
  • Research Site — Montpellier
  • Research Site — Saint-Herblain
  • Research Site — Suresnes

Michigan

  • Research Site — Ann Arbor
  • Research Site — Detroit

New York

  • Research Site — Buffalo
  • Research Site — New York

Arkansas

  • Research Site — Fayetteville

California

  • Research Site — Los Angeles

Massachusetts

  • Research Site — Boston

Rhode Island

  • Research Site — Providence

South Carolina

  • Research Site — Myrtle Beach

Trial Details

FieldValue
Enrollment Target 177 participants
Start Date 2025-10-01
Est. Completion 2029-01-18
Phase Phase 1

Sponsor

AstraZeneca

1,053 total trials

Interested in This Trial?

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07181161

The ClinicalTrials.gov registry entry for NCT07181161 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 177 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is AstraZeneca, which has 1,053 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Metastatic Prostate Cancer appearing as the primary indexed condition, and to 2 interventions — of which AZD9574 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07181161 reports 20 study locations spanning 9 distinct geographic areas — top geographies include Other, Michigan, New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07181161 about?

NCT07181161 is a clinical study titled "Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer". The main purpose of this study is to assess the safety and tolerability of AZD0516 as monotherapy and/or in combination with other anti-cancer agents for treatment of metastatic prostate cancer.

What is the current status of trial NCT07181161?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 177 participants. The study started on 2025-10-01. Estimated completion is 2029-01-18.

What conditions does trial NCT07181161 study?

This clinical trial studies the following conditions: Metastatic Prostate Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07181161?

The interventions under investigation include: AZD9574 (DRUG), AZD0516 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07181161?

This trial is sponsored by AstraZeneca, which has 1,053 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07181161 being conducted?

This trial has 20 study locations across Arkansas, California, Massachusetts, Michigan, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial