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NCT06267729 · ClinicalTrials.gov registry record · Phase 1

Study of AZD0754 in Participants With Metastatic Prostate Cancer

A Phase 1 study of Metastatic Prostate Cancer, sponsored by AstraZeneca.

Recruiting
Registry status
Phase 1
Development phase
60
Enrollment target
15
Study locations

NCT06267729 is a Phase 1 study of Metastatic Prostate Cancer that is actively recruiting participants, run by AstraZeneca. The registered enrollment target is 60 participants, below the 185-participant average among 41 other Metastatic Prostate Cancer trials with a reported enrollment target (68% lower). The trial reports 15 study locations across 11 states.

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The verdict

NCT06267729, a Phase 1 study of Metastatic Prostate Cancer, is actively recruiting participants, sponsored by AstraZeneca.

RECRUITING
Registry status
Phase 1
Development phase
60 participants
Enrollment target
15
Study locations

Study Summary

The purpose of this study is to evaluate the safety, tolerability, and antitumour activity of AZD0754 CAR T-cell therapy in participants with metastatic prostate cancer.

Conditions Studied

Metastatic Prostate Cancer

Interventions

  • BIOLOGICAL AZD0754
  • BIOLOGICAL AZD2287

Study Locations (15)

Massachusetts

  • Research Site - Boston
  • Research Site - Boston

New York

  • Research Site - New York
  • Research Site - New York

Texas

  • Research Site - Dallas
  • Research Site - Houston

Other

  • Research Site - East Melbourne
  • Research Site - Pamplona

California

  • Research Site - Duarte

Florida

  • Research Site - Tampa

Georgia

  • Research Site - Atlanta

Kansas

  • Research Site - Westwood

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2024-03-12
Est. Completion 2026-11-24
Phase Phase 1

Sponsor

AstraZeneca

1,285 total trials

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What the Registry Record Tells You About NCT06267729

The ClinicalTrials.gov registry entry for NCT06267729 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 185-participant average among 41 other Metastatic Prostate Cancer trials with a reported enrollment target (68% lower). The listed sponsor is AstraZeneca, which has 1,285 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Metastatic Prostate Cancer appearing as the primary indexed condition, and to 2 interventions - of which AZD0754 is the first listed.

NCT06267729 reports 15 study locations spanning 11 distinct geographic areas - top geographies include Massachusetts, New York, Texas.

Frequently Asked Questions

What is clinical trial NCT06267729 about?

NCT06267729 is a clinical study titled "Study of AZD0754 in Participants With Metastatic Prostate Cancer". The purpose of this study is to evaluate the safety, tolerability, and antitumour activity of AZD0754 CAR T-cell therapy in participants with metastatic prostate cancer.

What is the current status of trial NCT06267729?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 60 participants. The study started on 2024-03-12. Estimated completion is 2026-11-24.

What conditions does trial NCT06267729 study?

This clinical trial studies the following conditions: Metastatic Prostate Cancer.

What interventions are being tested in trial NCT06267729?

The interventions under investigation include: AZD0754 (BIOLOGICAL), AZD2287 (BIOLOGICAL).

Who is sponsoring clinical trial NCT06267729?

This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06267729 being conducted?

This trial has 15 study locations across California, Florida, Georgia, Kansas, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.