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NCT07177066 · ClinicalTrials.gov registry record · Phase 1
A Study of EDG-15400 in Healthy Adults
A Phase 1 study of Healthy Adults, sponsored by Edgewise Therapeutics.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 108
- Enrollment target
- 1
- Study location
NCT07177066: Recruiting Phase 1 study of Healthy Adults, sponsored by Edgewise Therapeutics.
NCT07177066 is a Phase 1 study of Healthy Adults that is actively recruiting participants, run by Edgewise Therapeutics. The registered enrollment target is 108 participants, above the 83-participant average among 33 other Healthy Adults trials with a reported enrollment target (30% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07177066, a Phase 1 study of Healthy Adults, is actively recruiting participants, sponsored by Edgewise Therapeutics.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 108 participants
- Enrollment target
- 1
- Study location
Study Summary
The purposes of this Phase 1 study of EDG-15400 are to: 1. Learn about the safety of EDG-15400 after single and multiple doses in healthy adults 2. Learn about how EDG-15400 is tolerated after single and multiples doses in healthy adults 3. Evaluate the amount of EDG-15400 in the blood and urine after single and multiple doses in healthy adults 4. Evaluate the effect of a meal on the amount of EDG-15400 that is in the blood in healthy adults 5. Evaluate whether the amount of EDG-15400 in the blood is similar for the suspension and tablet forms of EDG-15400 in healthy adults Participants will receive a single or multiple doses of EDG-15400 or a placebo by mouth.
Primary Outcome
To determine the safety and tolerability of EDG-15400 when administered as single and multiple ascending doses to healthy adults
Conditions Studied
Interventions
- DRUG Placebo
- DRUG EDG-15400
Study Locations (1)
Arizona
- Celerion, Inc. - Tempe
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 108 participants |
| Start Date | 2025-08-20 |
| Est. Completion | 2026-05 |
| Phase | Phase 1 |
What NCT07177066 shows while recruiting
NCT07177066 is an interventional study that assigns participants to a tested intervention. The registered 108 participants enrollment target is mid-sized for trials with a published cap, above the 83-participant average among 33 other Healthy Adults trials with a reported enrollment target (30% higher).
The record links to 1 condition, with Healthy Adults appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT07177066 reports a single indexed study location in Arizona.
Frequently Asked Questions
What is clinical trial NCT07177066 about?
NCT07177066 is a clinical study titled "A Study of EDG-15400 in Healthy Adults". The purposes of this Phase 1 study of EDG-15400 are to: 1. Learn about the safety of EDG-15400 after single and multiple doses in healthy adults 2. Learn about how EDG-15400 is tolerated after single and multiples doses in healthy adults 3. Evaluate the amount of EDG-15400 in the blood and urine af...
What is the current status of trial NCT07177066?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 108 participants. The study started on 2025-08-20. Estimated completion is 2026-05.
What conditions does trial NCT07177066 study?
This clinical trial studies the following conditions: Healthy Adults.
What interventions are being tested in trial NCT07177066?
The interventions under investigation include: Placebo (DRUG), EDG-15400 (DRUG).
Who is sponsoring clinical trial NCT07177066?
This trial is sponsored by Edgewise Therapeutics, which has 15 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07177066 being conducted?
This trial has 1 study location across Arizona. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy Adults
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07177066's enrollment target sits among peer trials
108 5th of 33 higher than 29 of 33 other Healthy Adults trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy Adults trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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