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NCT06815991 · ClinicalTrials.gov registry record · Phase 1
Phase 1a Single Ascending Dose Study of MIB-725 in Healthy Adults
A Phase 1 study of Healthy Adults, sponsored by Metro International Biotech.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 32
- Enrollment target
- 1
- Study location
NCT06815991 is a Phase 1 study of Healthy Adults that is actively recruiting participants, run by Metro International Biotech. The registered enrollment target is 32 participants, below the 86-participant average among 33 other Healthy Adults trials with a reported enrollment target (63% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06815991, a Phase 1 study of Healthy Adults, is actively recruiting participants, sponsored by Metro International Biotech.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 32 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a single center, open label (i.e. participants and study staff will not be masked to the intervention) single ascending dose study to evaluate the safety, tolerability, pharmaokinetics and pharmacodynamics of MIB-725 in community dwelling, healthy adults. Up to 4 successive groups (cohorts) of 8 subjects each will be enrolled in this trial. This study will determine the safety and tolerability of orally administered single ascending (increasing) doses (100, 200, 400, and 800 mg) of MIB-725 in healthy adults. The safety will be assessed by evaluating physical examination that includes an external eye examination, vital signs, adverse events, and changes in blood counts, EKG, urinalysis, coagulation measures, and blood chemistries, including but not limited to blood glucose, electrolytes, creatinine, liver function tests, uric acid, and creatine kinase.
Conditions Studied
Interventions
- DRUG MIB-725
Study Locations (1)
Massachusetts
- Brigham and Women's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2025-02-11 |
| Est. Completion | 2027-03 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06815991
The ClinicalTrials.gov registry entry for NCT06815991 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 32 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 86-participant average among 33 other Healthy Adults trials with a reported enrollment target (63% lower). The listed sponsor is Metro International Biotech, which has 5 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Healthy Adults appearing as the primary indexed condition, and to 1 intervention - of which MIB-725 is the first listed.
NCT06815991 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.
Frequently Asked Questions
What is clinical trial NCT06815991 about?
NCT06815991 is a clinical study titled "Phase 1a Single Ascending Dose Study of MIB-725 in Healthy Adults". This is a single center, open label (i.e. participants and study staff will not be masked to the intervention) single ascending dose study to evaluate the safety, tolerability, pharmaokinetics and pharmacodynamics of MIB-725 in community dwelling, healthy adults. Up to 4 successive groups (cohorts) ...
What is the current status of trial NCT06815991?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 32 participants. The study started on 2025-02-11. Estimated completion is 2027-03.
What conditions does trial NCT06815991 study?
This clinical trial studies the following conditions: Healthy Adults.
What interventions are being tested in trial NCT06815991?
The interventions under investigation include: MIB-725 (DRUG).
Who is sponsoring clinical trial NCT06815991?
This trial is sponsored by Metro International Biotech, which has 5 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06815991 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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