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NCT07161726 · ClinicalTrials.gov registry record · Phase 1
Cocoa to Maximize Exercise Training in Older Adults - The COMET Trial
A Phase 1 study, sponsored by University of Alabama at Birmingham.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 36
- Enrollment target
NCT07161726: Recruiting Phase 1 study, sponsored by University of Alabama at Birmingham.
NCT07161726 is a Phase 1 study that is actively recruiting participants, run by University of Alabama at Birmingham. The registered enrollment target is 36 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07161726, a Phase 1 study, is actively recruiting participants, sponsored by University of Alabama at Birmingham.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 36 participants
- Enrollment target
Study Summary
The purpose of the study is to see if regular exercise when combined with a cocoa supplement will improve physical performance and muscle strength compared to regular exercise alone.
Primary Outcome
We will assess exercise capacity of participants using the 6-min walk test, a safe and reliable test of aerobic endurance in older persons. This test has strong reproducibility, with intra-subject coefficients of variation averaging \< 10%, and has a modest correlation with peak VO2peak. Participants will be asked to walk as far and fast as possible for 6-min on a 60 m distance making u-turns at 60m and start line cones.
Interventions
- COMBINATION_PRODUCT (-)-Epicatechin-rich cocoa supplementation combined with exercise training
- COMBINATION_PRODUCT Placebo combined with exercise training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2026-04-21 |
| Est. Completion | 2027-12-31 |
| Phase | Phase 1 |
What NCT07161726 shows while recruiting
NCT07161726 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower).
The record links to 0 conditions, and to 2 interventions - of which (-)-Epicatechin-rich cocoa supplementation combined with exercise training is the first listed.
NCT07161726 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07161726 about?
NCT07161726 is a clinical study titled "Cocoa to Maximize Exercise Training in Older Adults - The COMET Trial". The purpose of the study is to see if regular exercise when combined with a cocoa supplement will improve physical performance and muscle strength compared to regular exercise alone.
What is the current status of trial NCT07161726?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2026-04-21. Estimated completion is 2027-12-31.
What interventions are being tested in trial NCT07161726?
The interventions under investigation include: (-)-Epicatechin-rich cocoa supplementation combined with exercise training (COMBINATION_PRODUCT), Placebo combined with exercise training (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT07161726?
This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07161726's enrollment target sits among peer trials
36 1210th of 2000 higher than 743 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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