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RECRUITING Phase 1

ABL103 in Combination With Pembrolizumab, With or Without Taxane in Advanced or Metastatic Solid Tumors

NCT07158918 · View on ClinicalTrials.gov ↗

Study Summary

This study is to assess the safety and antitumor activity of ABL103 plus pembrolizumab, with or without taxane, in advanced or metastatic solid tumors.

Conditions Studied

Interventions

  • DRUG KEYTRUDA® (pembrolizumab)
  • DRUG ABL103
  • DRUG Taxane

Study Locations (6)

Other

  • Seoul National University Bundang Hospital — Seongnam
  • Seoul National University Hospital — Seoul
  • Asan Medical Center — Seoul
  • Samsung Medical Center — Seoul

Ohio

  • UH Cleveland Medical Center — Cleveland

Victoria

  • PASO Medical — Frankston

Trial Details

FieldValue
Enrollment Target 65 participants
Start Date 2025-08-06
Est. Completion 2027-12-02
Phase Phase 1

Sponsor

ABL Bio

3 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07158918

The ClinicalTrials.gov registry entry for NCT07158918 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 65 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is ABL Bio, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Solid Tumors appearing as the primary indexed condition, and to 3 interventions — of which KEYTRUDA® (pembrolizumab) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07158918 reports 6 study locations spanning 3 distinct geographic areas — top geographies include Other, Ohio, Victoria. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07158918 about?

NCT07158918 is a clinical study titled "ABL103 in Combination With Pembrolizumab, With or Without Taxane in Advanced or Metastatic Solid Tumors". This study is to assess the safety and antitumor activity of ABL103 plus pembrolizumab, with or without taxane, in advanced or metastatic solid tumors.

What is the current status of trial NCT07158918?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 65 participants. The study started on 2025-08-06. Estimated completion is 2027-12-02.

What conditions does trial NCT07158918 study?

This clinical trial studies the following conditions: Solid Tumors. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07158918?

The interventions under investigation include: KEYTRUDA® (pembrolizumab) (DRUG), ABL103 (DRUG), Taxane (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07158918?

This trial is sponsored by ABL Bio, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07158918 being conducted?

This trial has 6 study locations across Ohio, Victoria. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial